Results 191 to 200 of about 47,915 (287)

Redirecting the Peptide Cleavage Causes Protease Inactivation

open access: yesAngewandte Chemie International Edition, Volume 64, Issue 31, July 28, 2025.
Cysteine proteases catalyze substrate cleavage by a two‐step acyl transfer mechanism. Newly designed peptidic inhibitors of human cathepsin B with N‐terminal carbamate warheads undergo a redirected cleavage and generate non‐canonical covalent complexes.
Christian Breuer   +20 more
wiley   +1 more source

Gastroprotective mechanisms of Citrus lemon (Rutaceae) essential oil and its majority compounds limonene and β-pinene: Involvement of heat-shock protein-70, vasoactive intestinal peptide, glutathione, sulfhydryl compounds, nitric oxide and prostaglandin E2

open access: hybrid, 2010
Ariane Leite Rozza   +7 more
openalex   +1 more source

Homocysteine: Canary in the Coal Mine or Hidden Threat? A Biochemical Study on the Role of Plasma Thiols

open access: yesThe FASEB Journal, Volume 39, Issue 13, 15 July 2025.
The figure illustrates how high plasma glutathione levels can promote the dethiolation of homocysteinylated proteins, leading to the release of homocysteine. The freed homocysteine is then either excreted through the kidneys or further processed via cellular metabolism, supporting homocysteine clearance and metabolic balance.
Daniela Giustarini   +3 more
wiley   +1 more source

Evaluation of total sulfhydryl levels and dietary habits in pemphigus vulgaris. [PDF]

open access: yesPostepy Dermatol Alergol
Ozaydın Yavuz G   +6 more
europepmc   +1 more source

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