Results 31 to 40 of about 1,126 (115)

CRISPR-Cas Adaptive Immune Systems of the Sulfolobales: Unravelling Their Complexity and Diversity

Life, 2015
The Sulfolobales have provided good model organisms for studying CRISPR-Cas systems of the crenarchaeal kingdom of the archaea. These organisms are infected by a wide range of exceptional archaea-specific viruses and conjugative plasmids, and their ...
Roger A. Garrett, Shiraz A. Shah, Susanne Erdmann, Guannan Liu, Marzieh Mousaei, Carlos León-Sobrino, Wenfang Peng, Soley Gudbergsdottir, Ling Deng, Gisle Vestergaard, Xu Peng, Qunxin She   +11 more
doaj   +1 more source

Virus-borne mini-CRISPR arrays are involved in interviral conflicts

Nature Communications, 2019
Here, the authors investigate the diversity and dynamics of the CRISPRome in the hyperthermophilic archaea of the order Sulfolobales, and find the most abundant spacers to come from mini-CRISPR arrays of archaeal viruses, which might represent a strategy
Sofia Medvedeva, Ying Liu, Eugene V. Koonin, Konstantin Severinov, David Prangishvili, Mart Krupovic   +5 more
doaj   +1 more source

Gain and loss of an intron in a protein-coding gene in Archaea: the case of an archaeal RNA pseudouridine synthase gene

BMC Evolutionary Biology, 2009
Background We previously found the first examples of splicing of archaeal pre-mRNAs for homologs of the eukaryotic CBF5 protein (also known as dyskerin in humans) in Aeropyrum pernix, Sulfolobus solfataricus, S. tokodaii, and S. acidocaldarirus, and also
Yokobori Shin-ichi, Itoh Takashi, Yoshinari Shigeo, Nomura Norimichi, Sako Yoshihiko, Yamagishi Akihiko, Oshima Tairo, Kita Kiyoshi, Watanabe Yoh-ichi   +8 more
doaj   +1 more source

Molecular mechanisms of regulation by a β‐alanine‐responsive Lrp‐type transcription factor from Acidianus hospitalis

MicrobiologyOpen, 2023
The leucine‐responsive regulatory protein (Lrp) family of transcriptional regulators is widespread among prokaryotes and especially well‐represented in archaea.
Amber J. Bernauw, Vincent Crabbe, Fraukje Ryssegem, Ronnie Willaert, Indra Bervoets, Eveline Peeters   +5 more
doaj   +1 more source

Archaeal Life on Tangkuban Perahu- Sampling and Culture Growth in Indonesian Laboratories

Hayati Journal of Biosciences, 2012
The aim of the expedition to Tangkuban Perahu, West Java was to obtain archaeal samples from the solfatara fields located in Domas crater. This was one of the places, where scientists from the University of Regensburg Germany had formerly isolated ...
SRI HANDAYANI, IMAN SANTOSO, HANS-JOACHIM FREISLEBEN, HARALD HUBER, ANDI, FERY ARDIANSYAH, CENMI MULYANTO, ZESSINDA LUTHFA, ROSARI SALEH, SERUNI KUSUMA UDYANINGSIH FREISLEBEN, SEPTELIA INAWATI WANANDI, MICHAEL THOMM   +11 more
doaj   +3 more sources

Evolution of complex RNA polymerases: the complete archaeal RNA polymerase structure.

PLoS Biology, 2009
The archaeal RNA polymerase (RNAP) shares structural similarities with eukaryotic RNAP II but requires a reduced subset of general transcription factors for promoter-dependent initiation.
Yakov Korkhin, Ulug M Unligil, Otis Littlefield, Pamlea J Nelson, David I Stuart, Paul B Sigler, Stephen D Bell, Nicola G A Abrescia   +7 more
doaj   +1 more source

Diversity of SIRV-like Viruses from a North American Population

Viruses, 2022
A small subset of acidic hot springs sampled in Yellowstone National Park yielded rod-shaped viruses which lysed liquid host cultures and formed clear plaques on lawns of host cells.
Joseph R. Fackler, Michael Dworjan, Khaled S. Gazi, Dennis W. Grogan   +3 more
doaj   +1 more source

CREAT: A CRISPR‐Based Genome Trimming Strategy for Systematic Identification of Dispensable Regions and Rapid Genome Reduction

Advanced Science, EarlyView.
Current genome‐reduction methods work in a trial‐and‐error fashion, constituting a long‐standing bottleneck in the research. We developed CREAT (CRISPR‐based genome trimming with a multi‐homology‐arm template), a CRISPR‐based genetic approach that enables systematically classifying essential versus non‐essential genomic regions and subsequently ...
Guanhua Yuan, Zhe Gao, Yingxuan Qi, Yang Zhang, Xuhui Tian, Pengpeng Zhao, Xu Feng, Qunxin She   +7 more
wiley   +1 more source

PolB1 Is Sufficient for DNA Replication and Repair Under Normal Growth Conditions in the Extremely Thermophilic Crenarchaeon Sulfolobus acidocaldarius

Frontiers in Microbiology, 2020
The thermophilic crenarchaeon Sulfolobus acidocaldarius has four DNA polymerases (DNAPs): PolB1, PolB2, PolB3, and Dbh (PolY). Previous in vitro studies suggested that PolB1 is the main replicative DNAP of Sulfolobales whereas PolB2 and Y-family ...
Hiroka Miyabayashi, Rupal Jain, Shoji Suzuki, Dennis W. Grogan, Norio Kurosawa   +4 more
doaj   +1 more source

Archaeal Tetraether Lipids as Tracers for Past Marine Environmental Change

Paleoceanography and Paleoclimatology, Volume 41, Issue 7, July 2026.
Abstract Archaea are single‐celled microorganisms that are abundant in marine environments and play a key role in the carbon and nitrogen cycles. Archaea can biosynthesize a wide variety of isoprenoid membrane lipids, including isoprenoid glycerol dibiphytanyl glycerol tetraethers (isoGDGTs).
Felix J. Elling, Gordon N. Inglis, Nina Davtian, Sarah J. Hurley, B. David A. Naafs, Lauren K. O'Connor, Richard D. Pancost, Francien Peterse, Ronnakrit Rattanasriampaipong, Addison Rice, Florence Schubotz, Jaap S. Sinninghe Damsté, Lars Wörmer, Alexandra Auderset, Kevin W. Becker, Melissa A. Berke, Peter K. Bijl, Cindy De Jonge, Liang Dong, Bella J. Duncan, Tom Dunkley Jones, Pierrick Fenies, Susanne Fietz, Sze Ling Ho, Arnaud Huguet, Carme Huguet, Jérôme Kaiser, Xiao‐Lei Liu, Gesine Mollenhauer, Sebastian Naeher, Ann Pearson, Kasia K. Śliwińska, Appy Sluijs, Claudia Sosa‐Montes de Oca, Qian Tian, Jessica E. Tierney, Devika Varma, Wenjie Xiao, Yi Ge Zhang, Xiaoxiao Zhao   +39 more
wiley   +1 more source