A TetR-family transcription factor regulates fatty acid metabolism in the archaeal model organism Sulfolobus acidocaldarius [PDF]
Nature Communications, 2019 Certain archaea appear to metabolize fatty acids, but the regulation of these pathways is unclear. Here, Wang et al. provide genetic, functional and structural evidence supporting that a TetR-family transcriptional regulator is involved in regulation of ...
Kun Wang +11 more
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Identification of the Genes Related to the Glycogen Metabolism in Hyperthermophilic Archaeon, Sulfolobus acidocaldarius [PDF]
Frontiers in Microbiology, 2021 Glycogen is a polysaccharide that comprises α-1,4-linked glucose backbone and α-1,6-linked glucose polymers at the branching points. It is widely found in organisms ranging from bacteria to eukaryotes.
Areum Lee +5 more
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The DNA Methylome of the Hyperthermoacidophilic Crenarchaeon Sulfolobus acidocaldarius [PDF]
Frontiers in Microbiology, 2018 DNA methylation is the most common epigenetic modification observed in the genomic DNA (gDNA) of prokaryotes and eukaryotes. Methylated nucleobases, N6-methyl-adenine (m6A), N4-methyl-cytosine (m4C), and 5-methyl-cytosine (m5C), detected on gDNA ...
Mohea Couturier, Ann-Christin Lindås
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Membrane Adaptations and Cellular Responses of Sulfolobus acidocaldarius to the Allylamine Terbinafine. [PDF]
Int J Mol Sci, 2023 Cellular membranes are essential for compartmentalization, maintenance of permeability, and fluidity in all three domains of life. Archaea belong to the third domain of life and have a distinct phospholipid composition.
Rao A, de Kok NAW, Driessen AJM.
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Transcriptome profiling of Nudix hydrolase gene deletions in the thermoacidophilic archaeon Sulfolobus acidocaldarius. [PDF]
Front Microbiol, 2023 Nudix hydrolases comprise a large and ubiquitous protein superfamily that catalyzes the hydrolysis of a nucleoside diphosphate linked to another moiety X (Nudix).
Breuer R +3 more
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kLa based scale-up cultivation of the extremophilic archaeon Sulfolobus acidocaldarius: from benchtop to pilot scale. [PDF]
Front Bioeng Biotechnol, 2023 The two major scale-up criteria in continuously stirred bioreactors are 1) constant aerated power input per volume (Pg/Vl), and 2) the volumetric O2 mass transfer coefficient (kla). However, Pg/Vl is only influenced by the stirrer geometry, stirrer speed,
Rastädter K +3 more
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Coordination of chromosome segregation and cell division in the archaeon Sulfolobus acidocaldarius. [PDF]
Nat CommunDespite its fundamental importance for the propagation of all cellular life, very little is known about the molecular basis of chromosome segregation in archaea.
Samson RY, Takemata N, Bell SD.
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Transcriptional and translational dynamics underlying heat shock response in the thermophilic crenarchaeon <i>Sulfolobus acidocaldarius</i>. [PDF]
mBio, 2023 High-temperature stress is critical for all organisms and induces a profound cellular response. For Crenarchaeota, little information is available on how heat shock affects cellular processes and on how this response is regulated.
Baes R +10 more
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The Impact of Single-Stranded DNA-Binding Protein SSB and Putative SSB-Interacting Proteins on Genome Integrity in the Thermophilic Crenarchaeon Sulfolobus acidocaldarius. [PDF]
Int J Mol Sci, 2023 The study of DNA repair in hyperthermophiles has the potential to elucidate the mechanisms of genome integrity maintenance systems under extreme conditions.
Suzuki S, Kurosawa N.
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Flow cytometry-based viability staining: an at-line tool for bioprocess monitoring of Sulfolobus acidocaldarius. [PDF]
AMB Express, 2022 Determination of the viability, ratio of dead and live cell populations, of Sulfolobus acidocaldarius is still being done by tedious and material-intensive plating assays that can only provide time-lagged results. Although S.
Rastädter K +4 more
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