Stability of mRNA in the hyperthermophilic archaeon Sulfolobus solfataricus
Archaea-like bacteria are prokaryotes but, in contrast, use eukaryotic-like systems for key aspects of DNA, RNA, and protein metabolism. mRNA is typically unstable in bacteria and stable in eukaryotes, but little information is available about mRNA half-lives in archaea.
Bini, Elisabetta +4 more
openaire +3 more sources
Transcriptional response to DNA damage in the archaeon Sulfolobus solfataricus [PDF]
Exposure of cells to DNA-damaging agents triggers a complex biological response involving cell cycle arrest and modulation of gene expression. Genomic sequencing has revealed the presence of archaeal genes homologous to components of the eucaryal nucleotide excision repair (NER) pathway, which is involved in the repair of ultraviolet (UV) light-induced
Salerno V +4 more
openaire +5 more sources
Nucleases: From Primitive Immune Defenders to Modern Biotechnology Tools
The evolution of nucleases is a remarkable journey, starting as primitive bacterial defenders against bacteriophages. Over time, nucleases have adapted to specialised roles within the immune systems of all forms of life, culminating in humans, where DNases and RNases serve as key components of the immune system.
Frank J. Hernandez
wiley +1 more source
Improving low-temperature activity of Sulfolobus acidocaldarius 2-keto-3-deoxygluconate aldolase
Sulfolobus acidocaldarius 2-keto-3-deoxygluconate aldolase (SacKdgA) displays optimal activity at 95 degrees C and is studied as a model enzyme for aldol condensation reactions.
Siemerink, M.A.J. +6 more
core +1 more source
Identification, characterization and classification of prokaryotic nucleoid‐associated proteins
Nucleoid‐associated proteins (NAPs) structure DNA by either bending, wrapping, bridging, or forming protein filaments on the DNA. We review newly identified NAPs and provide a list of simple biochemical assays to study the DNA‐structuring properties of novel NAPs. Abstract Common throughout life is the need to compact and organize the genome.
Samuel Schwab, Remus T. Dame
wiley +1 more source
Post-genomic characterization of metabolic pathways in Sulfolobus solfataricus
The physiological functions and mode of actions of different biomolecules are of continuous interest and a prerequisite to fully understand and appreciate the potential of Archaea and their molecules.
Walther, J.
core
Chromatin and gene regulation in archaea
Recent data from diverse archaea with different repertoires of nucleoid‐associated proteins show a common genome‐wide chromatin organisation where chromatin maintains access to gene promoters independently of transcription activity. Abstract The chromatinisation of DNA by nucleoid‐associated proteins (NAPs) in archaea ‘formats’ the genome structure in ...
Fabian Blombach, Finn Werner
wiley +1 more source
Regulation of DNA Topology in Archaea: State of the Art and Perspectives
DNA topoisomerases are ubiquitous enzymes that play a crucial role in regulating DNA supercoiling which affects fundamental biological processes involving DNA. In this review, we summarize the current understanding of regulation of supercoiling by DNA topoisomerases in the third domain of life, the Archaea, with a particular focus on three key model ...
Paul Villain, Tamara Basta
wiley +1 more source
Identification of novel components of the Ced and Ups systems in Saccharolobus islandicus REY15A
Abstract In Sulfolobales cells, transcription of the Ups (UV‐inducible pili of Sulfolobus) and Ced (Crenarchaeal system for exchange of DNA) genes is highly induced by DNA damage, and the two systems play key roles in pili‐mediated cell aggregation and chromosomal DNA import, respectively.
Pengju Wu +6 more
wiley +1 more source
Biotransformation of High Concentrations of Ginsenoside Substrate into Compound K by β-glycosidase from Sulfolobus solfataricus. [PDF]
Wang P, Tang C, Liu Y, Yang J, Fan D.
europepmc +1 more source

