Results 141 to 150 of about 71,069 (237)

A Convenient One‐Pot CuI‐Catalyzed Procedure for the Synthesis of S‐(N‐Heteroaryl) Thiocarboxylates From N‐Heteroaryl Bromides and Thiobenzoic Acid

open access: yesChemistryOpen, Volume 15, Issue 4, April 2026.
A one‐pot two‐step CuI‐catalyzed procedure for the synthesis of S‐(N‐heteroaryl) thiocarboxylates from N‐heteroaryl bromides and thiobenzoic acid was developed, which is highlighted by shorter reaction time, a smaller amount of iodide source and scalability.
Jiamin Pan   +4 more
wiley   +1 more source

Global Analysis of the Co‐Occurrence of Antimicrobial and Metal Resistance Genes in Bacterial Genomes From Dairy‐Isolated Pathogens

open access: yesEnvironmental Microbiology, Volume 28, Issue 4, April 2026.
Metal contamination in dairy systems drives antibiotic resistance through co‐selection. Analysis of 3303 genomes revealed 74% of isolates harbour more metal than AMR genes. Arsenic (arsB) and tetracycline (tet(38)) resistance co‐occur in 43% of bacteria, exhibiting nearly identical prevalence, suggesting a tight genetic linkage.
Arlen Carvalho de Oliveira Almeida   +8 more
wiley   +1 more source

From Covalent Traps to Fluorescent Beacons: The Expanding Arsenal of Chemical Probes for Studying Ubiquitin and Ubiquitin‐Like Proteins

open access: yesAngewandte Chemie, Volume 138, Issue 13, 23 March 2026.
A large variety of chemistry‐based ubiquitin probes have been developed. ABSTRACT Ubiquitin (Ub) and ubiquitin‐like proteins (Ubls) orchestrate diverse cellular processes through reversible post‐translational modification of target proteins. Their conjugation is governed by a cascade of E1 activating, E2 conjugating, and E3 ligating enzymes, while ...
Saibal Chanda, Wenshe Ray Liu
wiley   +2 more sources

Investigation on N-Aryl-2-(4-sulfamoylphenyl)hydrazine-1-carbothioamide as Human Carbonic Anhydrases Inhibitors. [PDF]

open access: yesPharmaceuticals (Basel)
Abdoli M   +7 more
europepmc   +1 more source

Classification of Platelet‐Activating Anti‐Platelet Factor 4 Disorders

open access: yesInternational Journal of Laboratory Hematology, Volume 48, Issue 2, Page 259-271, April 2026.
ABSTRACT Introduction The prototypic anti‐platelet factor 4 (PF4) disorder—heparin‐induced thrombocytopenia and thrombosis (HITT)—features immunoglobulin G (IgG) class antibodies that activate platelets, monocytes, and neutrophils in a mainly heparin‐dependent fashion via Fcγ receptor‐dependent cellular activation.
Theodore E. Warkentin
wiley   +1 more source

Evaluation of the Diagnostic Accuracy of the Quantitative Point‐of‐Care SD Biosensor Standard G6PD Test for Assessment of G6PD Deficiency in Infectious Diseases

open access: yesInternational Journal of Laboratory Hematology, Volume 48, Issue 2, Page 440-446, April 2026.
ABSTRACT Background G6PD deficiency affects about 500 million people worldwide and is prevalent in many malaria‐endemic settings. People with G6PD deficiency are at risk of hemolysis when exposed to certain medications, including 8‐aminoquinoline drugs used to treat Plasmodium vivax malaria.
Flavia Regina Medeiros da Silva   +7 more
wiley   +1 more source

Anomeric Amides: Valuable Reagents in Synthetic Organic Chemistry

open access: yesAngewandte Chemie, Volume 138, Issue 12, 16 March 2026.
Enabling late‐stage transformations and skeletal editing, anomeric amides have recently emerged as powerful synthetic tools. Due to their unique properties, anomeric amides have been employed in reactions ranging from amination to halogenation. This minireview provides an overview of recent progress in using anomeric amides across a variety of ...
Arushi Garg   +3 more
wiley   +2 more sources

Visible‐Light Mediated Functionalization in Phe‐Containing Peptides Upon a Debenzylative Amination Process

open access: yesAdvanced Synthesis &Catalysis, Volume 368, Issue 6, 17 March 2026.
Selective late‐stage modification of N‐terminal phenylalanine short peptides is achived by visible‐light initiated reaction with N‐iodoimides in a debenzylation–amination process. This metal‐free method permits the incorporation of N‐containing heterocycles into the α‐position of the peptide backbone.
Guillermo Morales‐Ortega   +4 more
wiley   +1 more source

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