Results 11 to 20 of about 86,041 (331)

Molecular mechanism of plasmid-borne resistance to sulfonamide antibiotics

open access: yesNature Communications, 2023
The sulfonamides (sulfas) are the oldest class of antibacterial drugs and inhibit the bacterial dihydropteroate synthase (DHPS, encoded by folP), through chemical mimicry of its co-substrate p-aminobenzoic acid (pABA).
M. Venkatesan   +9 more
semanticscholar   +1 more source

Recent Updates on the Synthesis of Bioactive Quinoxaline-Containing Sulfonamides

open access: yesApplied Sciences, 2021
Quinoxaline is a privileged pharmacophore that has broad-spectrum applications in the fields of medicine, pharmacology and pharmaceutics. Similarly, the sulfonamide moiety is of considerable interest in medicinal chemistry, as it exhibits a wide range of
Ali Irfan   +7 more
doaj   +1 more source

Synthesis of New N-Substituted N′-(2-methylthio-4-chloro-5-methylbenzenesulfonyl)guanidines with Anticancer Activity

open access: yesMedical Sciences Forum, 2022
Cancer is a disease that has spread widely throughout the world and requires the development of new anticancer drugs. Curing cancer is a complicated process as the drugs that are used target human cells and cells that have undergone genetic changes and ...
Beata Żołnowska   +2 more
doaj   +1 more source

Biosynthesis of sulfonamide and sulfamate antibiotics in actinomycete

open access: yesJournal of Industrial Microbiology & Biotechnology, 2021
Sulfonamides and sulfamates are a group of organosulfur compounds that contain the signature sulfamoyl structural motif. These compounds were initially only known as synthetic antibacterial drugs but were later also discovered as natural products.
T. Awakawa, Lena Barra, I. Abe
semanticscholar   +1 more source

Tetracycline and Sulfonamide Antibiotics in Soils: Presence, Fate and Environmental Risks

open access: yesProcesses, 2020
Veterinary antibiotics are widely used worldwide to treat and prevent infectious diseases, as well as (in countries where allowed) to promote growth and improve feeding efficiency of food-producing animals in livestock activities.
M. Conde-Cid   +5 more
semanticscholar   +1 more source

Is Blood a Good Indicator for Detecting Antimicrobials in Meat? Evidence for the Development of In Vivo Surveillance Methods

open access: yesAntibiotics, 2020
The introduction of antimicrobial residues in the food chain has a significant impact on human health. An innovative solution to avoid their presence in meat is the adaptation of current control methods for use with in vivo matrixes. Thus, the aim was to
María Jesús Serrano   +11 more
doaj   +1 more source

Influence of Sulfonamide Contamination Derived from Veterinary Antibiotics on Plant Growth and Development

open access: yesAntibiotics, 2020
Veterinary antibiotics such as sulfonamides are widely used to increase feed efficiency and to protect against disease in livestock production. The sulfonamide antimicrobial mechanism involves the blocking of folate biosynthesis by inhibiting bacterial ...
M. Cheong   +6 more
semanticscholar   +1 more source

Supramolecular synthon hierarchy in sulfonamide cocrystals with syn-amides and N-oxides

open access: yesIUCrJ, 2019
Sulfonamide drugs are well known antibacterial and antimicrobial molecules for pharmaceutical development. Building a library of suitable supramolecular synthons for the sulfonamide functional group and understanding their crystal structures with partner
Geetha Bolla, Ashwini Nangia
doaj   +1 more source

A Comparative Study on the Interaction of Sulfonamide and Nanosulfonamide with Human Serum Albumin

open access: yesJournal of Chemistry, 2013
Binding parameters of the N-phenyl benzene sulfonyl hydrazide, sulfonamide, and nanosulfonamide interaction with human serum albumin were determined by calorimetry method.
G. Rezaei Behbehani   +3 more
doaj   +1 more source

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