Results 101 to 110 of about 46,498 (299)

Copper-Mediated N-Heteroarylation of Primary Sulfonamides: Synthesis of Mono-N-heteroaryl Sulfonamides

, 2016
We describe the coupling of primary sulfonamides and various halogenated heterocyclic cores, with an emphasis on 2-heteroaryl halides, via copper catalysis. These studies enabled the synthesis of many new mono-N-heteroaryl sulfonamides.
Madelene Y. Hoe (2308468), B. Barry Touré (1920904), Jonathan Baffoe (2308471)   +2 more
core   +1 more source

Toward Chromoselective Transformations in Biological Systems: Perspectives and Challenges

Angewandte Chemie International Edition, EarlyView.
Controlling biological systems with small‐molecule chromophores has evolved into a powerful strategy and is applied from chemical biology to medicine. However, the complexity of in vivo systems cannot be matched by a single wavelength of light. Developing methods to combine and individually control multiple chromophores is crucial.
Nadja A. Simeth
wiley   +1 more source

Anticancer Sulfonamides Induce Splicing Factor RBM39 Degradation

, 2017
Anticancer sulfonamides produce aberrant splicing by inducing degradation of the splicing factor RBM39.

core   +1 more source

Modeling the hydrolysis of perfluorinated compounds containing carboxylic and phosphoric acid ester functions, alkyl iodides, and sulfonamide groups

, 2009
Temperature dependent rate constants were estimated for the acid- and base-catalyzed and neutral hydrolysis reactions of perfluorinated telomer acrylates (FTAcrs) and phosphate esters (FTPEs), and the SN1 and SN2 hydrolysis reactions of fluorotelomer ...
Sierra Rayne, Kaya Forest
core  

Unlocking Catalyst Activation as a Critical Bottleneck in Cross‐Coupling Reactions: Room‐Temperature Couplings of Weak Nucleophiles Enabled by [Pd(1‐MeNAP)TFA]2 Precatalysts

Angewandte Chemie International Edition, EarlyView.
In many Pd‐catalyzed cross‐couplings, catalyst performance has been found to be limited by catalyst activation. Methylnaphthyl (MeNAP) palladium trifluoroacetate dimers are presented as easy‐to‐store and easy‐to‐handle precursors, which rapidly activate under reaction conditions, even when only weakly coordinating, non‐reducing nucleophiles are present.
Sourav Manna, Henric F. Janning, Nikolaos V. Tzouras, Jane Anto Simplica Sagayaraj, Fadil Faizal Mannighayil, Angelino Doppiu, Lukas J. Gooßen   +6 more
wiley   +1 more source

Comparative Mobility of Sulfonamides and Bromide Tracer in Three Soils

, 2011
In animal agriculture, sulfonamides are one of the routinely used groups of antimicrobials for therapeutic and sub-therapeutic purposes. It is observed that, the animals when administered the antimicrobials, often do not completely metabolize them; and ...
Kurwadkar, Sudarshan T., Kurwadkar, W, Meyer, M, Dana W. Kolpin, Craig D. Adams, Meyer, Michael T., Kolpin, Dana W., Sudarshan T. Kurwadkar, Kolpin, D, Michael T. Meyer, Adams, Craig D.   +10 more
core   +1 more source

New sulfonamides containing organometallic-acylhydrazones: synthesis, characterisation and biological evaluation as inhibitors of human carbonic anhydrases

Journal of Enzyme Inhibition and Medicinal Chemistry, 2019
A series of organometallic acylhydrazones was prepared, incorporating Re(CO)3, Mn(CO)3 and ferrocenyl moieties, which were subsequently reacted with amino-sulfonamides in order to obtain carbonic anhydrase (CA, EC 4.2.1.1) inhibitors possessing ...
Yosselin Huentupil, Luis Peña, Néstor Novoa, Emanuela Berrino, Rodrigo Arancibia, Claudiu T. Supuran   +5 more
doaj   +1 more source

Polymorphism in Secondary Benzene Sulfonamides

, 2016
The role of about 20 different solvents in the crystallization of polymorphs for 13 N-phenyl benzene sulfonamides was studied. Five compounds (1, 2, 3, 7, and 11) are dimorphic, and one is trimorphic (6).
Ashwini Nangia (1400761), Bipul Sarma (604086), Palash Sanphui (1607602)   +2 more
core   +2 more sources

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

A simple copper salt catalyzed N-arylation of amines, amides, imides, and sulfonamides with arylboronic acids

, 2004
A simple copper salt catalyzed N-arylation reaction with arylboronic acids is reported. In the presence of a catalytic amount of a simple copper salt, the coupling of arylboronic acids with imides was performed in MeOH to give N-arylimides in excellent ...
Chen, L, You, JS, Lan, JB, Xie, RG, Yan, M, Yu, XQ, Sichuan Univ, Dept Chem, Chengdu 610064, Peoples R China., Yu, XQ, Zhang, GL   +7 more
core