Results 121 to 130 of about 46,498 (299)

Polymorphism in secondary benzene sulfonamides

, 2010
The role of about 20 different solvents in the crystallization of polymorphs for 13 N-phenyl benzene sulfonamides was studied. Five compounds (1, 2, 3, 7, and 11) are dimorphic, and one is trimorphic (6).
Bipul Sarma, Ashwini Nangia, Palash Sanphui, Nangia, Ashwini, Sanphui, Palash, Sarma, Bipul   +5 more
core   +1 more source

Flipping the Card With Enantiodivergent Organocatalysis

Chemistry – A European Journal, EarlyView.
This minireview elaborates on recent organocatalytic strategies for achieving enantiodivergence—the ability to access both product enantiomers using a single chiral catalyst. It highlights how achiral stimuli, such as solvent polarity and chemical additives, along with minimal catalyst modifications, trigger stereochemical inversions in reactions ...
Debora Iapadre, Alessio Carioscia, Alessandro Brusa, Armando Carlone   +3 more
wiley   +1 more source

Generation of Sulfamoyl Radical for the Modular Synthesis of Sulfonamides

Efficient synthesis of sulfonamides has long been pursued by chemists due to their frequent occurrence in pharmaceuticals, especially in anti-inflammatory medicines.
Kramer, Søren, Zhang, Xuemei, Lian, Zhong, Lv, Haiping, Chen, Xinzhou   +4 more
core   +2 more sources

Study on the Rapid Limit Test for Six Sulfonamide Residues in Food Based on the TLC-SERS Method

Molecules
Sulfonamides are not only widely applied in clinics but also highly valued in animal husbandry. Recently, it has become common for sulfonamide residues to exceed the standard limits in food, which can affect human health.
Yukun Ma, Min Zhang, Li Li, Jicheng Liu, Feng Xu, Yuanrui Wang, Bo Song, Tao Xu, Yue Hong, Honglian Zhang   +9 more
doaj   +1 more source

SO2 Transfer Enabled by an Easy‐to‐Handle Ionic Liquid

Chemistry – A European Journal, EarlyView.
Best of both worlds: The ionic liquid [NEt3Me][Cl(SO2)n] unites the atom economy and low cost of sulfur dioxide with the safety and applicability of common surrogates, streamlining SO2 transfer to access to 3‐sulfolenes, sulfonamides, and SuFEx reagents.
Johanna S. Sturm, Letizia Lanfredi, Severin Erbertseder, Marius Balizs, Patrick Voßnacker, Simon Steinhauer, Merlin Kleoff, Anja Wiesner, Niklas Limberg, Patrick Pröhm, Franz‐Lucas Haut, Sebastian Riedel   +11 more
wiley   +1 more source

Precision Chemistry for Protein Lysine Modification

Chemistry – A European Journal, EarlyView.
Selective modification of lysine residues is challenging due to their similar intrinsic reactivity. Inspired by enzymatic recognition, ligand‐guided electrophiles enable site‐selective labeling and functionalization, while ligand‐guided catalyses achieve regioselective installation of bio‐relevant post‐translational modifications.
Mayu Onoda, Motomu Kanai
wiley   +1 more source

Organelle‐Resolved Tetrazine‐trans‐Cyclooctene Click Chemistry for Cargo Delivery and Release

Chemistry – A European Journal, EarlyView.
Bioorthogonal click chemistry tools provide a means for specific intracellular conjugation of molecules. In this study, we used reactive tetrazine (Tz) and TCO moieties for labeling of organelles and organelle‐specific delivery and activation of doxorubicin prodrugs.
Oleh Durydivka, Marek Chovanec, Rastislav Dzijak, Michal Rahm, Jachym Hrusak, Paul E. Reyes‐Gutierrez, Milan Vrabel   +6 more
wiley   +1 more source

Synthesis, Characterization, Antioxidant Evaluation, Cytotoxicity Studies, and Molecular Docking of Novel Sulfonamide Derivatives. [PDF]

J Biochem Mol Toxicol
A series of novel sulfonamide derivatives (4a–i) were synthesized and characterized. Compound 4d showed significant antioxidant activity, while compounds 4g, 4h, and 4i exhibited high cytotoxicity against ovarian and prostate cancer cells, particularly 4h with a log IC50 of 1.343 µg/mL.
Bouraoui O, Şekerci G, Mesbah K, Ezugwu JA, Benkiniouar R, Tekin S, Küçükbay F, Boulebd H, Küçükbay H.   +8 more
europepmc   +2 more sources

Nickel‐Catalyzed Reductive Cross‐Coupling of Xanthate Esters With Aryl and Alkenyl Iodides

Chemistry – A European Journal, EarlyView.
A nickel‐catalyzed reductive cross‐coupling of xanthate esters and aryl/alkenyl iodides is reported without the need for separate activators for the xanthate esters. The reaction utilizes a relatively low catalyst loading. Diarylmethanes with a good functional group variety can thus be synthesized indirectly from the corresponding benzylic alcohols ...
Felix Vöhringer, Kathrin Zwettler, Dmitry I. Sharapa, Felix Studt, Ivana Fleischer   +4 more
wiley   +1 more source

One‐Shot Pd(II)‐Catalyzed Multiple C–H Activation Enables Modular Construction of Fluorenylidene Oxindole‐Based Multi(Polycyclic) Aromatic Enes

Chemistry – A European Journal, EarlyView.
A one‐shot Pd(II)‐catalyzed C─H activation strategy enables the rapid conversion of simple linear propiolamides into structurally diverse mono‐, di‐, and tri‐olefin‐bridged MPAEs. This cascade process orchestrates up to six sequential C–H activations in a single operation, providing streamlined access to highly conjugated architectures.
Haiyu Wang, Kouki Sakata, Takuma Sato, Masahiro Terada, Tienan Jin   +4 more
wiley   +1 more source