Results 141 to 150 of about 110,887 (393)

Evaluating Prescriber Adherence to Guideline-Based Treatment Pathways of a Newly Initiated Antimicrobial Stewardship Program at a Rehabilitation Hospital [PDF]

open access: yes, 2017
Background: Inappropriate use of antimicrobials in the healthcare setting is associated with consequences including antimicrobial resistance, Clostridium difficile infection (CDI), adverse drug reactions, and increased healthcare costs.
Bertram, Christie
core   +1 more source

Advances in Mechanochemical Methods for One‐Pot Multistep Organic Synthesis

open access: yesChemistry – A European Journal, Accepted Article.
Mechanochemical synthesis has emerged as a powerful and more sustainable alternative to conventional solution‐based methods, offering advantages such as no or only minimal solvent use, reduced reaction times, and simplified operational conditions.
Michael Schnürch, Nina Biedermann
wiley   +1 more source

Sulfonamides in the environment: a review and a case report

open access: yes, 2018
Sulfonamides are widely used in treatment of animals and humans but pose a risk as environmental pollutants. An analysis of 1588 publications focused on sulfonamides is presented here.
K. Hruška, M. Fránek
semanticscholar   +1 more source

Polymerase Synthesis of Hypermodified DNA Displaying a Combination of Thiol, Hydroxyl, Carboxylate, and Imidazole Functional Groups in the Major Groove

open access: yesChemistry – A European Journal, EarlyView.
A series of 2’‐deoxyribonucleoside 5’‐O‐triphosphates bearing functional groups of amino acid side chains in enzyme active sites (OH, SH, COOH, and imidazole) were synthesized and used for enzymatic synthesis of hypermodified DNA displaying these substituents in the major groove mimicking peptides or proteins. Abstract We designed and synthesized a set
Lukáš Kaiser   +4 more
wiley   +1 more source

Biodegradable ion-exchange microspheres based on modified polylysines [PDF]

open access: yes, 1995
Poly-L-lysine was synthesized via a triethylamine initiated ring-opening polymerization of Z-L-lysine-N'~-carboxyanhydride,\ud followed by deprotection of the E-amino group. Subsequently the polylysine was sulfamated using a pyridinium-sulfate complex to
Cremers, H.F.M.   +3 more
core   +4 more sources

Strategy‐Level Prodrug Synthesis

open access: yesChemistry – A European Journal, Accepted Article.
Organic synthesis uniquely provides opportunities to access molecules that serve defined purposes. Medicinal chemistry illustrates this attribute well with prodrug design, whereby a drug undergoes a late‐stage conversion to a conditionally responsive active medicinal agent (AMA), being a notable example.
Paul Geaneotes, Paul Floreancig
wiley   +1 more source

Reactions of p-Nitrophenyloxirane with Amines Containing Fragments with Bicyclic Skeleton [PDF]

open access: yes, 2002
Reactions of p-nitrophenyloxirane with amines containing fragments with bicyclic skeleton of norbornene, norbornane, epoxynorbornane (stereoisomeric exo- and endo-5-aminomethylbicyclo[2.2.1]hept-2-enes, N-benzyl-endo-5-aminomethylbicyclo[2.2.1]hept-2-ene,
Golodaeva, E. A.   +3 more
core  

Highly Chemoselective NH- and O-Transfer to Thiols Using Hypervalent Iodine Reagents: Synthesis of Sulfonimidates and Sulfonamides.

open access: yesOrganic Letters, 2018
Aryl thiols can be selectively converted to sulfonimidates or sulfonamides with three new S-X connections being made selectively in one pot. Using hypervalent iodine reagents in the presence of ammonium carbamate, NH- and O-groups are transferred under ...
Arianna Tota   +7 more
semanticscholar   +1 more source

Membran‐Bioreaktor‐Technik kombiniert mit nachgeschalteter Ozonung – Vergleich mit konventionellen Ozonanwendungen Combination of Membrane Bioreactor and Downstream Ozonation – A Comparison to Conventional Ozone Applications

open access: yesChemie Ingenieur Technik, EarlyView.
Kommunale Kläranlagen gelten als Haupteintragspfad organischer Mikroschadstoffe in die aquatische Umwelt. Ein Großteil der Arzneimittelrückstände und Industriechemikalien wird in Kläranlagen nicht oder nur teilweise entfernt. Um einen qualitativ höheren Kläranlagen‐Ablauf zu erzeugen, wird eine Kombination aus hybridem Teilstrom‐Membran‐Bioreaktor mit ...
Maximilian Werner   +4 more
wiley   +1 more source

Survey of Tetracyclines, Sulfonamides, Sulfamethazine, and Quinolones in UHT Milk in China Market

open access: yesJournal of Integrative Agriculture, 2013
This study surveyed 180 samples of ultra high temperature (UHT) milk of four top Chinese dairy brands collected in the 25 cities in China in June 2011, and assessed their contamination with antibiotics, using the ELISA method.
Rong-wei HAN   +5 more
doaj  

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