Results 151 to 160 of about 76,467 (269)

A Pilot Study on the Prevalence and Characterization of Multidrug‐Resistant Gram‐Negative Bacteria in Chicken and Pork Meat Around Kathmandu District, Nepal

MicrobiologyOpen, Volume 15, Issue 2, April 2026.
This study investigated multidrug resistance in Gram‐negative bacteria from chicken and pork meat in Kathmandu, isolating 136 strains from 13 samples. Nearly half were multidrug resistant, highlighting contaminated meat as a potential route for zoonotic transmission and the need for antimicrobial resistance monitoring in Nepal.
Sushma Paudel, Sumitra Tamang, Preety Singh, Rishav Das, Sushmita Paudel, Astha Shakya   +5 more
wiley   +1 more source

Electrochemical One-Step Synthesis of Alkyne Sulfonates and Sulfonamides: Building Blocks for Highly Substituted Alkenes and 1,3-Butadienes. [PDF]

JACS Au
Azizzade M, Breitschaft FA, Waldvogel SR, Opatz T.   +3 more
europepmc   +1 more source

Antimicrobial Effect of Spices and Their Phytochemicals: A Novel Approach to Overcoming Antibiotic Resistance

MedComm, Volume 7, Issue 4, April 2026.
This graphical abstract shows the antibacterial potential of phytochemicals from 15 spices, showcasing key compounds, their extraction methods, and mechanisms of action. It highlights membrane disruption, ROS generation, enzyme inhibition, and biofilm prevention as core antibacterial pathways.
Hettiyahandi Binodh De Silva, Yanqi Dai, Shervanthi Homer‐Vanniasinkam, Mohan Edirisinghe   +3 more
wiley   +1 more source

Non‐redox Lewis Acids Supported Pd‐Catalyzed C—C /C—H Activation and Accession to Produce Pharmaceutical Intermediates

ChemistryOpen, Volume 15, Issue 4, April 2026.
Palladium is a simple and versatile redox‐active metal that plays a crucial role in the oxidation reactions for organic synthesis and production of pharmaceutical intermediates. Notably, there has been significant progress with Lewis acids (LAs), which are non‐redox metal ions promoting Pd(II)‐catalyzed oxidation via C—H and C—C bond activation.
Ahmed M. Senan, Senem Akkoc, A. M. Abdulkarem, Sadeq K. Alhag   +3 more
wiley   +1 more source

From Covalent Traps to Fluorescent Beacons: The Expanding Arsenal of Chemical Probes for Studying Ubiquitin and Ubiquitin‐Like Proteins

Angewandte Chemie, Volume 138, Issue 13, 23 March 2026.
A large variety of chemistry‐based ubiquitin probes have been developed. ABSTRACT Ubiquitin (Ub) and ubiquitin‐like proteins (Ubls) orchestrate diverse cellular processes through reversible post‐translational modification of target proteins. Their conjugation is governed by a cascade of E1 activating, E2 conjugating, and E3 ligating enzymes, while ...
Saibal Chanda, Wenshe Ray Liu
wiley   +2 more sources

Design, synthesis, molecular docking and cytotoxic evaluation of novel pyrimidine-based sulfonamide derivatives as potent anticancer agents: SAR insights and biological profiling. [PDF]

Sci Rep
Bayoumy NM, Fadda AA, Gaffer HE, Soliman NN.   +3 more
europepmc   +1 more source

ZnFe2O4@SiO2@AC Magnetic Nanocomposite as an Efficient Catalyst for Ultrasound‐Assisted Azidation of Aryl Halides to Aryl Amines

ChemistryOpen, Volume 15, Issue 4, April 2026.
nanocomposite catalyst was synthesized, demonstrating a reliable approach that underscores its innovative potential in the azidation of aryl halides, followed by their conversion to aryl amines. In this study, a novel ZnFe2O4@SiO2@AC nanocomposite catalyst was synthesized, demonstrating a reliable approach that underscores its innovative potential in ...
Manish Kumar, Rima Heider Al Omari, Soumya V. Menon, Shaker Al‐Hasnaawei, Ahmad Sajjadi, Amrita Pal, Renu Sharma, Aashna Sinha   +7 more
wiley   +1 more source

Efficacy of sulfonamides targeting malic enzyme in an animal model of Chagas disease. [PDF]

Front Pharmacol
Dos Santos TCF, da Silva RB, de Sousa IL, Naciuk FF, Marchese L, Eufrásio AG, Lobo-Rojas AE, Giampauli RM, de Souza VB, Schenka AA, Bruder M, Rocco SA, Cordeiro AT.   +12 more
europepmc   +1 more source

A Convenient One‐Pot CuI‐Catalyzed Procedure for the Synthesis of S‐(N‐Heteroaryl) Thiocarboxylates From N‐Heteroaryl Bromides and Thiobenzoic Acid

ChemistryOpen, Volume 15, Issue 4, April 2026.
A one‐pot two‐step CuI‐catalyzed procedure for the synthesis of S‐(N‐heteroaryl) thiocarboxylates from N‐heteroaryl bromides and thiobenzoic acid was developed, which is highlighted by shorter reaction time, a smaller amount of iodide source and scalability.
Jiamin Pan, Suting Xie, Yong Li, Jiang Wu, Guilong Zhao   +4 more
wiley   +1 more source

Synthesis of unprotected thienyl sulfonamides and their activities against carbapenem-resistant <i>Klebsiella pneumoniae</i>, docking studies and ADMET analysis. [PDF]

RSC Adv
Bilal M, Noreen M, Usman Qamar M, Siddique F, Rasool N, Imran M.   +5 more
europepmc   +1 more source