Results 21 to 30 of about 76,467 (269)
Pharmacy, 2019 As one of the earliest developed antimicrobial classes, sulfonamides remain important therapeutic options for the empiric and definitive treatment of various infectious diseases. In the general population, approximately 3–8% of patients are reported to experience a sulfonamide allergy. Sulfonamide allergies can result in various physical manifestations;
Amber Giles +3 more
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PLoS ONE, 2020 BackgroundSulfonamides are widely used to treat infectious diseases during pregnancy. However, the safety of maternal exposure to sulfonamides is controversial.
Peixuan Li +3 more
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Journal of Dermatological Treatment, 2023 Aim To emphasize the role of non-sulfonamides in the treatment of Nocardia infection and reduce the adverse reactions caused by sulfonamides. Methods We retrospectively analyzed a case of cutaneous nocardiosis in an immunocompetent individual.
Youqi Ji +6 more
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Socio-historical analysis of the social importance of pharmacovigilance
Frontiers in Sociology, 2022 Pharmacovigilance is a scientific discipline that has changed a lot in recent years and is of great social importance. The case of the so-called sulfonamide elixir showed society the importance of this discipline.
Juan R. Coca +2 more
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Methylfolate Trap Promotes Bacterial Thymineless Death by Sulfa Drugs. [PDF]
PLoS Pathogens, 2016 The methylfolate trap, a metabolic blockage associated with anemia, neural tube defects, Alzheimer's dementia, cardiovascular diseases, and cancer, was discovered in the 1960s, linking the metabolism of folate, vitamin B12, methionine and homocysteine ...
Marissa B Guzzo +14 more
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Synthesis, Structural Elucidation, and Biological Potential of Novel Sulfonamide Drugs
Bioscientific Review, 2022 Sulfonamides are anti-microbial and anti-inflammatory agents used widely for the treatment of infections. The current research dealt with the synthesis of four sulfonamides formed by the reaction of p-toluenesulfonyl chloride with 4-amino phenyl acetic ...
Shabbir Hussain +4 more
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Journal of AOAC International, 2020 BACKGROUND Sulfonamides have been widely used in the prevention and clinical treatment of bacterial diseases in livestock and poultry. The use of sulfonamides increases the risk of veterinary drug residues in animal derived foods.
Xiaoyun Duan +8 more
semanticscholar +1 more source
Enzymatic Transformation and Bonding of Sulfonamide Antibiotics to Model Humic Substances
Journal of Chemistry, 2015 Sulfonamides are consumed as pharmaceutical antibiotics and reach agricultural soils with excreta used as fertilizer. Subsequently, nonextractable residues rapidly form in soil, which has been researched in a couple of studies.
J. Schwarz +3 more
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Molecules, 2022 Nowadays, the discovery of a new non-toxic metal complex with biological activity represents a very active area of research. Two Cu+2 complexes, [Cu(L1)2(H2O)3] (C1) (HL1= N-(5-(4-methylphenyl)-[1,3,4]–thiadiazole–2-yl)-naphtalenesulfonamide) and [Cu(L2 ...
Adriana Corina Hangan +6 more
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Molecules, 2022 In this paper, we present for the first time the evaluation of cytotoxicity and genotoxicity of de novo synthesized pyrazolo[4,3-e]tetrazolo[1,5-b][1,2,4]triazine sulfonamides MM129, MM130, and MM131 in human tumor cell lines: HeLa, HCT 116, PC-3, and ...
Karol Bukowski +4 more
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