Results 11 to 20 of about 46,498 (299)
PLoS ONE, 2020 BackgroundSulfonamides are widely used to treat infectious diseases during pregnancy. However, the safety of maternal exposure to sulfonamides is controversial.
Peixuan Li +3 more
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Journal of Dermatological Treatment, 2023 Aim To emphasize the role of non-sulfonamides in the treatment of Nocardia infection and reduce the adverse reactions caused by sulfonamides. Methods We retrospectively analyzed a case of cutaneous nocardiosis in an immunocompetent individual.
Youqi Ji +6 more
doaj +1 more source
Unified Approach to Benzo[d]thiazol-2-yl-Sulfonamides
, 2021 In this paper, we report a unified approach to N-substituted and N,N-disubstituted benzothiazole (BT) sulfonamides. Our approach to BT-sulfonamides starts from simple commercially available building blocks (benzo[d]thiazole-2-thiol and primary and ...
Ondřej Kováč (5143211) +9 more
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Metal-free Three-Component Synthesis of 1,2,3-Triazoline-4-sulfonamides
, 2021 A new type of diazo compounds, namely, CH-diazomethane sulfonamides (generated in situ from readily available α-acetyl-α-diazomethane sulfonamides), was employed in a 1,3-dipolar cycloaddition reaction with imines (also formed in situ from primary ...
Mikhail Krasavin +9 more
core +1 more source
Socio-historical analysis of the social importance of pharmacovigilance
Frontiers in Sociology, 2022 Pharmacovigilance is a scientific discipline that has changed a lot in recent years and is of great social importance. The case of the so-called sulfonamide elixir showed society the importance of this discipline.
Juan R. Coca +2 more
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Synthesis, Structural Elucidation, and Biological Potential of Novel Sulfonamide Drugs
Bioscientific Review, 2022 Sulfonamides are anti-microbial and anti-inflammatory agents used widely for the treatment of infections. The current research dealt with the synthesis of four sulfonamides formed by the reaction of p-toluenesulfonyl chloride with 4-amino phenyl acetic ...
Shabbir Hussain +4 more
doaj +1 more source
Methylfolate Trap Promotes Bacterial Thymineless Death by Sulfa Drugs. [PDF]
PLoS Pathogens, 2016 The methylfolate trap, a metabolic blockage associated with anemia, neural tube defects, Alzheimer's dementia, cardiovascular diseases, and cancer, was discovered in the 1960s, linking the metabolism of folate, vitamin B12, methionine and homocysteine ...
Marissa B Guzzo +14 more
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Sulfonamides and trimethoprim [PDF]
Expert Review of Anti-infective Therapy, 2009 Sulfonamides and trimethoprim are inexpensive and effective antibacterial drugs that have been used extensively. The use of sulfonamides for systemic use has, however, decreased dramatically for several years, mainly because of resistance development in pathogenic bacteria and allergic side effects. Also the clinical efficiency of trimethoprim has been
openaire +2 more sources
Enzymatic Transformation and Bonding of Sulfonamide Antibiotics to Model Humic Substances
Journal of Chemistry, 2015 Sulfonamides are consumed as pharmaceutical antibiotics and reach agricultural soils with excreta used as fertilizer. Subsequently, nonextractable residues rapidly form in soil, which has been researched in a couple of studies.
J. Schwarz +3 more
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Molecules, 2022 Nowadays, the discovery of a new non-toxic metal complex with biological activity represents a very active area of research. Two Cu+2 complexes, [Cu(L1)2(H2O)3] (C1) (HL1= N-(5-(4-methylphenyl)-[1,3,4]–thiadiazole–2-yl)-naphtalenesulfonamide) and [Cu(L2 ...
Adriana Corina Hangan +6 more
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