Results 81 to 90 of about 112,315 (335)

New Cu⁺² Complexes with N-Sulfonamide Ligands: Potential Antitumor, Antibacterial, and Antioxidant Agents

Molecules, 2022
Nowadays, the discovery of a new non-toxic metal complex with biological activity represents a very active area of research. Two Cu+2 complexes, [Cu(L1)2(H2O)3] (C1) (HL1= N-(5-(4-methylphenyl)-[1,3,4]–thiadiazole–2-yl)-naphtalenesulfonamide) and [Cu(L2 ...
Adriana Corina Hangan, Alexandru Turza, Roxana Liana Lucaciu, Bogdan Sevastre, Emőke Páll, Luminița Simona Oprean, Gheorghe Borodi   +6 more
doaj   +1 more source

Enantioselective Radical Construction of 5-Membered Cyclic Sulfonamides by Metalloradical C-H Amination.

Journal of the American Chemical Society, 2019
Both arylsulfonyl and alkylsulfonyl azides can be effectively activated by the cobalt(II) complexes of D2-symmetric chiral amidoporphyrins for enantioselective radical 1,5-C-H amination to stereoselectively construct 5-membered cyclic sulfonamides.
Yang Hu, K. Lang, Chaoqun Li, Joseph B. Gill, Isaac Kim, Hongjian Lu, K. B. Fields, McKenzie K. Marshall, Q. Cheng, X. Cui, L. Wojtas, X. P. Zhang   +11 more
semanticscholar   +1 more source

New sulfonamides containing organometallic-acylhydrazones: synthesis, characterisation and biological evaluation as inhibitors of human carbonic anhydrases

Journal of Enzyme Inhibition and Medicinal Chemistry, 2019
A series of organometallic acylhydrazones was prepared, incorporating Re(CO)3, Mn(CO)3 and ferrocenyl moieties, which were subsequently reacted with amino-sulfonamides in order to obtain carbonic anhydrase (CA, EC 4.2.1.1) inhibitors possessing ...
Yosselin Huentupil, Luis Peña, Néstor Novoa, Emanuela Berrino, Rodrigo Arancibia, Claudiu T. Supuran   +5 more
doaj   +1 more source

Practical access to axially chiral sulfonamides and biaryl amino phenols via organocatalytic atroposelective N-alkylation

Nature Communications, 2019
The importance of axial chirality in enantioselective synthesis has been widely recognized for decades. The practical access to certain structures such as biaryl amino phenols known as NOBINs in enantiopure form, however, still remains a challenge.
Shenci Lu, S. Ng, K. Lovato, Jun-Yang Ong, S. Poh, Xiao Qian Ng, L. Kürti, Yu Zhao   +7 more
semanticscholar   +1 more source

Interfacial Photoelectrochemistry in Organic Synthesis

Angewandte Chemie International Edition, Accepted Article.
Photoelectrodes have traditionally enjoyed widespread attention as heterogeneous catalysts for the activation of water and CO2 in energy research, while photoelectrochemistry with homogeneous molecular catalysts dominates the activations of more complex molecules in organic synthesis.
Gabriel Chan, Daria Corsi, Oleksandr Savateev, Paolo Giusto, Joshua Philip Barham   +4 more
wiley   +1 more source

An unusual successful treatment with non-sulfonamides: primary cutaneous nocardiosis caused by Nocardia brasiliensis

Therapeutics and Clinical Risk Management, 2018
Nian Chen, Qin Qin, Ke-Dai Sun, Dan Luo, Qiong-Hui Cheng Department of Dermatology, Daping Hospital, Army Medical University, Chongqing 400042, China Introduction: Primary cutaneous nocardiosis is a rare suppurative or granulomatous inflammation ...
Chen N, Qin Q, Sun KD, Luo D, Cheng QH
doaj  

DEVELOPMENT AND VALIDATION OF A SIMPLE AND FAST METHOD FOR SULFONAMIDES, TETRACYCLINES AND MACROLIDES IN HONEY USING LC-MS/MS

Drug Analytical Research, 2018
Antibacterial are widely used in veterinary applications for diseases treatment and prophilatic purposes. Inadequate uses of these drugs can lead of undesirable residues in honey for consumption.
Cristina Belissimo Ribeiro, Magda Targa Martins, Louise Jank, Fabiano Barreto, Rodrigo Barcellos Hoff , Juliana Bazzan Arsand   +5 more
doaj   +1 more source

Mechanochemical Strategies Applied to the Late‐Stage Modifications of Pharmaceutically Active Compounds

Angewandte Chemie International Edition, Accepted Article.
This review explores the potential of mechanochemistry in the late‐stage modification of active pharmaceutical ingredients (APIs), offering a comprehensive analysis of methods designed to transform structurally complex molecular scaffolds. By examining the scope, efficiency, and mechanistic aspects of these approaches, the review highlights protocols ...
Johanna Templ, Lars Borchardt
wiley   +1 more source

Removal of nutrients from water column and physiological responses of Vallisneria natans under sulfonamide stress

Journal of Freshwater Ecology, 2019
For a better understanding of the metabolic adaptations to sulfonamide (SA) stress in submerged macrophytes, the alterations of nutrient element uptake and secondary metabolism were studied in the leaves of Vallisneria natans (Lour.) Hara exposed to 0 ...
Houtao Xu, Liming Zhu, Liqing Wang, Xiaoyan Zheng, Linkui Cao   +4 more
doaj   +1 more source

Safety of sulfamethoxazole–trimethoprim for the treatment of bacterial infection in outpatient settings: A systematic review and meta‐analysis with active comparator disproportionality analysis

British Journal of Clinical Pharmacology, EarlyView.
Aims Sulfamethoxazole–trimethoprim (SMX‐TMP) is a widely used antibiotic for treating bacterial infections, but its safety in adult outpatients remains understudied. This systematic review and meta‐analysis evaluated the safety profile of SMX‐TMP and identified critical research gaps.
Rebecca Preyra, Lujain Ez Eddin, Fatemeh Ahmadi, Atefeh Jafari, Flory T. Muanda   +4 more
wiley   +2 more sources