Results 61 to 70 of about 13,320 (204)

Radical allylation with a-branched allyl sulfones

, 2008
International audience(Chemical Equation Presented) Branching out with sulfones: The use of allyl isopropyl sulfones solves the problem of premature isomerization and allows the radical addition of xanthates to a-branched allyl sulfones (see scheme; DCE ...
Nicolas Charrier, Zard, Samir, Z., Samir Z. Zard, Charrier, Nicolas   +3 more
core   +1 more source

Synthesis of New Active Sulfones in the 5-Nitroimidazole Series

Molecules, 2002
We describe here the preparation of new 5-nitroimidazoles which are known to have an efficacy against metronidazole-susceptible and -resistant Giarda, Trichomonas, and Entamoeba spp. The multi-step synthesis uses electron transfer methodology.
Patrice Vanelle, Thierry Terme, Kamel Benakli   +2 more
doaj   +1 more source

Synthesis of ω-Methylsulfinyl- and ω-Methylsulfonylalkyl Glucosinolates

Molecules
General pathways were devised to synthesize ω-methylsulfinyl- and ω-methylsulfonylalkyl glucosinolates, which represent an important class of structurally homogeneous plant specialized metabolites.
Manolis Mavratzotis, Stéphanie Cassel, Gina Rosalinda De Nicola, Sabine Montaut, Patrick Rollin   +4 more
doaj   +1 more source

Desulfurization of Dibenzothiophene and Oxidized Dibenzothiophene Ring Systems

Molecules, 2010
Lithium, used in conjunction with sodium metal, produces a high yield of biphenyl when reacted with dibenzothiophene, dibenzothiophene sulfoxide or dibenzothiophene sulfone.
Diego P. Morales, Alexander S. Taylor, Steven C. Farmer   +2 more
doaj   +1 more source

Synthesis and Promising in Vitro Antiproliferative Activity of Sulfones of a 5-Nitrothiazole Series

Molecules, 2012
 The synthesis in water of new sulfone derivatives under microwave irradiation is described. This eco-friendly process leads to the expected products in good yields by reaction of various substituted sulfinates (commercially available or ...
Nadine Azas, Patrice Vanelle, Pascal Rathelot, Maxime D. Crozet, Anita Cohen   +4 more
doaj   +1 more source

Rh-Catalyzed Asymmetric Hydrogenation of α‑Substituted Vinyl Sulfones: An Efficient Approach to Chiral Sulfones

, 2017
Rh/(S)-(+)-DTBM-Segphos complex catalyzed asymmetric hydrogenation of α-substituted vinyl sulfones has been achieved, furnishing the desired products in high yields and excellent enantioselectivities (>90% yield, up to 99% ee).
Xumu Zhang (1447558), Liyang Shi (1676794), Xuguang Yin (3773191), Biao Wei (1628221), Hui Lv (1537975), Peng Xue (219948)   +5 more
core   +1 more source

Sulfones: A New Functional Group for Modular Radical Cross-Coupling [PDF]

, 2017
Cross-coupling chemistry comprises the vast majority of reactions employed in the synthesis of medicines, agrochemicals, and other functional materials.
Deng-Hui, Bao, Philippe, Nuhant, Phil, Baran, Guanda, Che, Michael R., Collins, Monika M., Kruszyk, James J., Mousseau, Lijie, Sun, Wenhua, Qiao, Gary M., Gallego, Cheng, Bi, Jacob T., Edwards, Rohan R., Merchant, Tian, Qin   +13 more
core   +2 more sources

Fluorescence-based proteasome activity profiling [PDF]

, 2011
With the proteasome emerging as a therapeutic target for cancer treatment, accurate tools for monitoring proteasome (inhibitor) activity are in demand.
Jong, A., Rodenko, B., Berkers, C.R., Schuurman, K.G., Ovaa, H., Boris Rodenko, Annemieke de Jong, Celia R. Berkers, Karianne G. Schuurman, Huib Ovaa   +9 more
core   +1 more source

Radical Titanocene Promoted Coupling of Epoxides and Vinyl Sulfones [PDF]

, 2015
[EN]A radical coupling reaction of diverse vinyl sulfones and epoxides was mediated by Cp2TiCl (Cp = cyclopentadienyl) to provide a straightforward synthetic pathway to hydroxy sulfones. The reaction was successfully achieved by using either an excess or
Encinas Madrazo, Soledad, Herrero Teijón, Pablo, Rubio González, María Rosa, Fernández Mateos, Alfonso   +3 more
core   +1 more source

The study of the antimicrobial activity of 6-sulfonyl derivatives of 4-methyl-1,2- dihydroquinoline-2-one

Annals of Mechnikov's Institute, 2020
Experimental study of the antimicrobial activity of the nineteen new 6-R-sulfonyl derivatives of 4-methyl-1,2- dihydroquinolin-2-one has been carried out using the wells method and the serial dilution method in liquid medium.
T Tsapko
doaj