Results 61 to 70 of about 26,603 (276)
Protonation and anion-binding properties of aromatic sulfonylurea derivatives
, 2021 In this work the anion-binding properties of three aromatic sulfonylurea derivatives in acetonitrile and dimethyl sulfoxide were explored by means of NMR titrations. It was found that the studied receptors effectively bind anions of low basicity (Cl−, Br−
Barišić, Dajana +4 more
core +1 more source
International Journal of Cancer, EarlyView.ABSTRACT This multicenter retrospective study evaluated the impact of type 2 diabetes mellitus (DM) on clinical outcomes and immune‐related adverse events (irAEs) in 450 patients with metastatic non‐small cell lung cancer (NSCLC) treated with second‐line nivolumab at 17 centers between 2016 and 2024. Among these patients, 118 (26.2%) had DM.
Emre Çakır +32 more
wiley +1 more source
Design, Synthesis, Activity and Docking Study of Sorafenib Analogs Bearing Sulfonylurea Unit
Molecules, 2015 Two series of novel sorafenib analogs containing a sulfonylurea unit were synthesized and their chemical structures were confirmed by 1H-NMR, 13C-NMR, MS spectrum and elemental analysis.
Chunjiang Wu +6 more
doaj +1 more source
Research Progress of Berberine in Kidney Disease: Targeting Mitochondria and Ferroptosis
iNew Medicine, EarlyView.This figure illustrates the model‐specific renoprotective mechanisms of berberine (BBR) across three major kidney diseases. From left to right, the diagram shows that BBR targets distinct core pathways depending on the pathological context: in diabetic nephropathy (DN), BBR activates AMPK to improve mitochondrial energy metabolism; in acute kidney ...
Liuqing Wang +3 more
wiley +1 more source
Planta Daninha, 2007 Foi avaliada a eficácia no controle de arroz-vermelho com o herbicida nicosulfuron ou a mistura formulada de imazethapyr + imazapic. O experimento foi conduzido em casa de vegetação da Faculdade de Agronomia Eliseu Maciel (UFPel), no município de Capão ...
L.C. Fontana +5 more
doaj +1 more source
Conformational Polymorphism in Sulfonylurea Drugs: Electronic Structure Analysis
, 2016 Quantum chemical calculations have been performed using HF, B3LYP, and MP2 methods on the model sulfonylurea PhSO2NHC(O)NHMe to understand the conformational and tautomeric preferences.
Nikunj K. Patel (2268253) +3 more
core +1 more source
Artificial intelligence‐assisted nanozyme design for medical and environmental applications
Journal of Intelligent Medicine, EarlyView.AI‐assisted nanozyme design integrates cross‐source data and machine learning to enable predictive structure‐activity relationships, accelerating intelligent diagnostics, precision therapeutics, and environmental surveillance. Abstract Nanozymes, a class of nanomaterials with intrinsic enzyme‐like catalytic activities, have emerged as promising ...
Xiaolin Guo +7 more
wiley +1 more source
Protein & Cell, 2018 ATP-sensitive potassium channels (KATP) are energy sensors on the plasma membrane. By sensing the intracellular ADP/ATP ratio of β-cells, pancreatic KATP channels control insulin release and regulate metabolism at the whole body level.
Jing-Xiang Wu +5 more
doaj +1 more source
SEPARATION OF SULFONYLUREA METABOLITES IN WATER BY CAPILLARY ELECTROPHORESIS
, 1995 The potential of capillary electrophoresis (CE) for the separation and detection of the metabolites of nine sulfonylurea herbicides in aqueous solution was evaluated.
VICARI A, BONETTI A, DINELLI G
core +1 more source
Journal of Magnetic Resonance Imaging, EarlyView.ABSTRACT Background Epicardial adipose tissue (EAT) is a metabolically active fat depot associated with cardiovascular risk and represents a modifiable imaging biomarker. Studies have shown that sodium–glucose cotransporter‐2 (SGLT2) inhibitors reduce EAT thickness in patients with type 2 diabetes mellitus (T2DM). However, it is unclear whether this is
Min Jae Cha +9 more
wiley +1 more source