Results 21 to 30 of about 27,055 (203)

Impact of Antidiabetic Drugs on Clinical Outcomes of COVID-19: A Nationwide Population-Based Study [PDF]

Endocrinology and Metabolism
Background Inconsistent results have been reported regarding the association between the use of antidiabetic drugs and the clinical outcomes of coronavirus disease 2019 (COVID-19). This study aimed to investigate the effect of antidiabetic drugs on COVID-
Han Na Jang, Sun Joon Moon, Jin Hyung Jung, Kyung-Do Han, Eun-Jung Rhee, Won-Young Lee   +5 more
doaj   +1 more source

Characterization of the rat mesangial cell type 2 sulfonylurea receptor [PDF]

, 1999
Background. Sulfonylurea receptors are classified as either high- affinity type 1 (SUR1) or low-affinity type 2 receptors (SUR2), and the gene expression of SURs has recently been demonstrated in kidney. However, functional data regarding a renal SUR are
Garvin, Jeffrey L, Rodríguez-Barbero, Alicia, Riser, Bruce L, Cortes, Pedro, Szamosfalvi, Balázs, Asano, Kenichiro, Yee, Jerry   +6 more
core   +1 more source

MODY3 in the child with type 2 diabetes mellitus phenotype: case report

Сахарный диабет, 2013
MODY is a heterogeneous group of diseases that stem from certain genetic mutations and are characterized by beta-cell dysfunction, early clinical onset (before the age of 25) and autosomal dominant inheritance.
Tamara Leonidovna Kuraeva, Elena Alexandrovich Sechko, Irina Alexandrovna Eremina, O N Ivanova, Sergey Alexandrovich Prokof’ev   +4 more
doaj   +1 more source

Comparison of diabetes phenotype in children and their mothers with permanent neonatal diabetes mellitus carrying the same KCNJ11 variants

Endocrine Regulations, 2020
Objective. Mutations of the KCNJ11 gene are the most common cause of the permanent neonatal diabetes mellitus (PNDM). Majority of people with KNCJ11-PNDM have a de-novo mutation.
Stanik Juraj, Barak Lubomir, Dankovcikova Adriana, Valkovicova Terezia, Skopkova Martina, Gasperikova Daniela   +5 more
doaj   +1 more source

Pharmacogenetics of sulfonylurea-induced hypoglycemia in type 2 diabetes patients: The SUCLINGEN study

, 2021
Aim: This study investigated the incidence of sulfonylurea-induced hypoglycemia and its predictors in Type 2 diabetes (T2D) patients. Patients & methods: In this prospective, observational study, T2D patients on maximal sulfonylurea-metformin therapy ...
Vethakkan, Shireene Ratna, Hussein, Zanariah, Huri, Hasniza Zaman, Loganadan, Navin Kumar   +3 more
core   +1 more source

Assessing the environmental risks of sulfonylurea pollutants: Insights into the risk priority and structure-toxicity relationships

Ecotoxicology and Environmental Safety
Sulfonylureas are widely used herbicides globally; however, the health risks associated with exposure to these compounds are poorly understood. This study used fuzzy clustering to categorize 44 sulfonylurea compounds into three risk priority levels (I ...
Zhi-Cong He, Tao Zhang, Xin-Fang Lu, Rui Li, Wei Peng, Fei Ding   +5 more
doaj   +1 more source

Efeitos da adubação nitrogenada em cobertura sobre a seletividade de herbicidas à cultura do milho Effects of cover nitrogen fertilization on herbicide selectivity in corn

Planta Daninha, 2006
O objetivo deste trabalho foi avaliar os efeitos da adubação nitrogenada de cobertura sobre a seletividade dos herbicidas aplicados em pós-emergência na cultura do milho (Zea mays). Para isso, foram conduzidos dois experimentos.
M. Nicolai, R.F. López Ovejero, S.J.P. Carvalho, M.S. Moreira, P.J. Christoffoleti   +4 more
doaj   +1 more source

Conformational Polymorphism in Sulfonylurea Drugs: Electronic Structure Analysis

, 2010
Quantum chemical calculations have been performed using HF, B3LYP, and MP2 methods on the model sulfonylurea PhSO2NHC(═O)NHMe to understand the conformational and tautomeric preferences.
Kasetti, Yoganjaneyulu, Nikunj K. Patel, Bharatam, Prasad V., Yoganjaneyulu Kasetti, Prasad V. Bharatam, Patel, Nikunj K., Sandeep Sundriyal, Sundriyal, Sandeep, Nikunj K. Patel (2268253), Prasad V. Bharatam (662055), Yoganjaneyulu Kasetti (2044738), Sandeep Sundriyal (1884100)   +11 more
core   +2 more sources

Evidence for the Application of Emerging Technologies to Accelerate Crop Improvement – A Collaborative Pipeline to Introgress Herbicide Tolerance Into Chickpea

Frontiers in Plant Science, 2021
Accelerating genetic gain in crop improvement is required to ensure improved yield and yield stability under increasingly challenging climatic conditions.
Janine Croser, Janine Croser, Dili Mao, Dili Mao, Nicole Dron, Simon Michelmore, Simon Michelmore, Larn McMurray, Christopher Preston, Dylan Bruce, Francis Chuks Ogbonnaya, Federico Martin Ribalta, Julie Hayes, Judith Lichtenzveig, William Erskine, Brian Cullis, Tim Sutton, Tim Sutton, Kristy Hobson   +18 more
doaj   +1 more source

Severe hypoglycemia in users of sulfonylurea antidiabetic agents and antihyperlipidemics

, 2016
Drug-drug interactions causing severe hypoglycemia due to antidiabetic drugs is a major clinical and public health problem. We assessed whether sulfonylurea use with a statin or fibrate was associated with severe hypoglycemia. We conducted cohort studies
S Cardillo, Brensinger, Colleen M., Bilker, Warren B., S Hennessy, Gagne, Joshua J., Cardillo, Serena, X Han, Leonard, Charles E., CE Leonard, Han, Xu, JH Flory, JJ Gagne, DA Flockhart, Flockhart, David A., WB Bilker, Hennessy, Sean, CM Brensinger, Flory, James H.   +17 more
core   +1 more source