Integrating Conventional and Emerging Approaches in Cardiovascular Risk Assessment and Management
Conventional risk factors (hypertension, dyslipidaemia, diabetes, smoking, obesity and physical inactivity) account for roughly 70% of population‐attributable cardiovascular risk and anchor a proposed three‐tier pathway: universal low‐cost assessment (Tier 1), selective testing such as hsCRP or PRS where it would change management (Tier 2) and resource‐
Sana Rasheed +4 more
wiley +1 more source
Evaluation of %CV and average glucose derived from pre- and postprandial 6-point glucose measurements for assessing hypoglycemia risk. [PDF]
Soga R +4 more
europepmc +1 more source
ABSTRACT Background Hip and knee replacement are common procedures with an increasing focus on same‐day surgery. However, capacity constraints limit the number of eligible patients actually being scheduled for same‐day discharge, calling for further selection of those with the highest likelihood of same‐day discharge.
Christoffer C. Jørgensen +11 more
wiley +1 more source
Screening of binding by antidiabetic drugs to normal vs AGE-modified human serum albumin through covalent immobilization and microscale affinity chromatography. [PDF]
Woolfork AG +3 more
europepmc +1 more source
ABSTRACT Aims There is no proven treatment to prevent the growth or rupture of abdominal aortic aneurysm (AAA). As an aneurysm enlarges over time, the risk of fatal aortic rupture increases. Metformin, a drug usually prescribed to treat Type 2 diabetes, has previously been associated with reduced AAA risk in observational studies. Our aim was to assess
Katie Louise Saxby +5 more
wiley +1 more source
The Impact of Polymers in Amorphous Solid Dispersion on the Bioavailability of Sulfonylureas and Meglitinides. [PDF]
Aulifa DL +8 more
europepmc +1 more source
Sexual Safety Signals of Common Antidiabetic Drugs: Insights From FAERS Disproportionality Analysis
ABSTRACT Background Erectile dysfunction is a prevalent and distressing complication of diabetes mellitus that markedly affects quality of life in male patients. Although the role of diabetes in erectile dysfunction is well‐established, potential drug‐induced sexual dysfunction associated with commonly prescribed antidiabetic medications remains ...
Shan Lin +3 more
wiley +1 more source
Predictors of Glycemic Response to Sulfonylurea Therapy in Type 2 Diabetes Over 12 Months: Comparative Analysis of Linear Regression and Machine Learning Models. [PDF]
Garg S +4 more
europepmc +1 more source
ABSTRACT Aim Patients with chronic kidney disease (CKD) have an increased cardiovascular risk. Since neutrophils and neutrophil‐borne proteins contribute to cardiovascular disease, we analyzed the neutrophil phenotype in patients with CKD who presented with a spectrum of cardiovascular comorbidities.
Sonja Vondenhoff +22 more
wiley +1 more source
Discovery of novel quinazoline-sulfonamide derivatives with promising antidiabetic activity. [PDF]
Zayed MF +4 more
europepmc +1 more source

