Results 91 to 100 of about 1,586,237 (267)

Person‐Reported and Continuous Glucose Monitoring (CGM) Recorded Hypoglycaemia in People With Insulin‐Treated Type 2 Diabetes and Mild to Moderate Chronic Kidney Disease; Post Hoc Analysis From the Hypo‐METRICS Study

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background and Aims People with diabetes and chronic kidney disease (CKD) may be at increased risk of iatrogenic hypoglycaemia. We compared rates of sensor‐detected (SDH) and person‐reported hypoglycaemia (PRH) in people with insulin‐treated Type 2 diabetes (T2D) with and without CKD in the Hypo‐METRICS study.
Julie M. B. Brøsen   +39 more
wiley   +1 more source

Changes in the Activity and Selectivity of Herbicides by Selective Fluorine Substitution, Taking Bentranil and Classic® Analogues as Examples

open access: yesCHIMIA, 2004
The introduction of fluorine atoms into 2-phenyl-4H-3,1-benzoxazin-4-one (bentranil) led to sweeping changes in its herbicidal properties in some cases, and 5-fluoro-2-phenyl-4H-3,1-benzoxazin-4-one ('fluorobentranil') was found to be the most ...
Gerhard Hamprecht   +2 more
doaj   +1 more source

GLUT2 and glucokinase expression is coordinately regulated by sulfonylurea

open access: yes, 1999
In the present study we examined the effect of sulfonylurea on the expression of the glucose transporter GLUT2 and the glucose phosphorylating enzyme Glucokinase (GK) in beta TC6-F7 cells; furthermore, we studied the modifications induced by sulfonylurea
Federici M   +8 more
core   +1 more source

Genetic and Clinical Determinants of Variation in Drug Response in Type 2 Diabetes: Insights From the Scottish and UK Biobank Cohorts

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Objective Treatment response in type 2 diabetes (T2D) varies widely among individuals. This study aimed to quantify the contributions of clinical characteristics and genetic predisposition as measured through partitioned polygenic risk scores (pPRS) to variation in glycemic response to glucose‐lowering therapies.
S. Garg   +4 more
wiley   +1 more source

Metabolomic insights into the intricate gut microbial–host interaction in the development of obesity and type 2 diabetes

open access: yesFrontiers in Microbiology, 2015
Gut microbiota has recently been proposed as a crucial environmental factor in the development of metabolic diseases such as obesity and type 2 diabetes, mainly due to its contribution in the modulation of several processes including host energy ...
Magali ePalau-Rodriguez   +6 more
doaj   +1 more source

Estimating the effect of sulfonylurea on HbA1c in diabetes: a systematic review and meta-analysis [PDF]

open access: yes, 2013
AIMS/HYPOTHESIS: Sulfonylureas are widely prescribed glucose-lowering medications for diabetes, but the extent to which they improve glycaemia is poorly documented.
R. J. Stevens   +13 more
core   +1 more source

Additive Glucagonotropic and Insulinotropic Effects of Glucose‐Dependent Insulinotropic Polypeptide and Alanine in Fasted Healthy Men

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims/Hypothesis Glucose‐dependent insulinotropic polypeptide (GIP) is a bidirectional glucose‐stabilising hormone potentiating insulin secretion at high glucose levels and glucagon secretion during normal‐to‐low plasma glucose levels. Preclinically, GIP and the amino acid alanine show synergistic glucagonotropic effects at low glucose levels ...
Julie Warnøe   +13 more
wiley   +1 more source

Investigation of background contribution from different solvent brands used for sample preparation and analysis of persistent organic pollutants [PDF]

open access: yes, 2023
In the times of pandemic, we experienced problems with supply bottlenecks for the solvents normally used for extraction and analysis of persistent organic pollutants (POPs; i.e. PCBs, PBDEs and organochlorine pesticides) in our laboratory and, considered
Brox, Jan   +3 more
core  

Exploratory Analysis of Type 2 Diabetes Mellitus Metabolic Phenotypes and Their Association With Vitamin D Status in Primary Care Patients

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims This study aimed to perform an exploratory characterisation of metabolic phenotypes in primary care patients with type 2 diabetes mellitus (T2DM), using a predefined approach and examine their association with vitamin D status. Materials and Methods This cross‐sectional study included 178 participants randomly selected in Sergipe, Brazil.
Liliane Viana Pires   +10 more
wiley   +1 more source

Sulfonylurea herbicides

open access: yes, 1991
Available from British Library Document Supply Centre- DSC:q91/15871(Sulfonylurea) / BLDSC - British Library Document Supply CentreSIGLEGBUnited ...
Smith, C   +1 more
core  

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