Results 151 to 160 of about 5,907 (256)

Potassium channel-targeted therapy in reducing vascular complications in diabetes mellitus: novel insights. [PDF]

Front Pharmacol
Rajkovic J, Ribic A, Rekovic L, Gostimirovic M, Bukarica A, Terzic D, Gojkovic-Bukarica L.   +6 more
europepmc   +1 more source

KCNK16 Deficiency Deteriorates Body Growth and Diet‐Independently Decreases Lipid Accumulation in Mice

Comprehensive Physiology, Volume 16, Issue 3, June 2026.
Loss of KCNK16 in mice alters β‐cell insulin secretion dynamics leading to increased pancreatic insulin content and decreased circulating IGF‐1. Furthermore, body growth and adiposity were reduced independent of dietary interventions. Despite these changes, overall glucose tolerance and insulin sensitivity remain largely preserved.
Olena Früh, Jennifer Winkler, Jana M. Jäger, Rongwan Sun, Aoxue Liu, Niklas Hegemann, Jana Grune, Atsuyo Ikeda, Andreas Diefenbach, Matthias Schäfer, Uwe Schwahn, Johann Gassenhuber, Klaus Steinmeyer, Joachim Spranger, Knut Mai, Sebastian Brachs   +15 more
wiley   +1 more source

Long-term efficacy and safety of tirzepatide in participants with type 2 diabetes with inadequate glycaemic control on metformin and/or sulfonylurea: Post-hoc analysis of SURPASS-4. [PDF]

Diabetes Obes Metab
Guan H, Jiang H, Yuan H, Sun J, Xu J, Ji L.   +5 more
europepmc   +1 more source

Harnessing Fatty Acid By‐Products for Diabetes Management: Insights From Nutritional and Biological Research

eFood, Volume 7, Issue 3, June 2026.
Bioactive fatty acids from agro‐industrial byproducts are highlighted as a promising avenue for managing diabetes in this review, which aims to develop targeted interventions for optimal utilization and therapeutic benefits. ABSTRACT Diabetes mellitus (DM), influenced by multifaceted factors, creates a complex imbalance within the body. Nutrition plays
Youssef Elouafy, Abdelaali Balahbib, Meriem El Fessikh, Saïd Gharby, Nasreddine El Omari, Waleed Al Abdulmonem, Gokhan Zengin, Abdelhakim Bouyahya   +7 more
wiley   +1 more source

Partial restoration of counterregulatory circulating glucagon by dapagliflozin and low-dose glibenclamide in men with type 1 diabetes: in vitro studies and randomised clinical crossover trial. [PDF]

EBioMedicine
Gao R, Spiliotis I, Dou H, Hill TG, Kothegala L, Miranda C, Abiakam N, Coleman RL, White S, Adler A, Rorsman P.   +10 more
europepmc   +1 more source

Functional Bread From Bambara Groundnut and Orange Peel Attenuates Hyperglycemia and Oxidative Stress in a High‐Fat Diet/Streptozotocin‐Induced Type 2 Diabetes Rat Model

Food Chemistry International, Volume 2, Issue 2, Page 211-221, June 2026.
This study evaluated Bambara groundnut–wheat composite bread fortified with orange peel in diabetic rats. Diets significantly lowered blood glucose, inhibited α‐glucosidase and α‐amylase, and boosted antioxidant enzymes compared to controls. Results emphasize BG‐based functional foods' potential to help manage type 2 diabetes through regulation of ...
S. O. Oguntuase, O. W. Fasakin, I. S. Oyeleye, G. Oboh   +3 more
wiley   +1 more source

The neurobiological regulatory mechanism of brain edema. [PDF]

Front Cell Neurosci
Tian M, Li M, Zhang C, Luo Q, Wang A, Li D.   +5 more
europepmc   +1 more source

The Effect of Carvacrol on Lipid Profiles, Oxidative Stress, Inflammatory Markers, and Renal Injury in STZ‐Induced Diabetic Rats

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
Carvacrol administration is associated with improvements in lipid profiles, attenuation of oxidative stress, and modulation of inflammatory markers, including C‐reactive protein (CRP). The diagram summarizes systemic effects across major organs, highlighting potential protective roles against inflammation‐related oxidative damage and kidney injury ...
Vida Seyedmousavi Dijvejin, Vahid Asghariazar, Helda Tutunchi, Elnaz Faramarzi, Hamed Shoorei, Rouhallah Moradpour, Mehdi Asghari Vostakolaei   +6 more
wiley   +1 more source

Rationale, design and baseline characteristics of the TRANSCEND-CKD trial of retatrutide in patients with chronic kidney disease. [PDF]

Nephrol Dial Transplant
Heerspink HJL, van Raalte DH, Bjornstad P, Bunck MC, Wu P, Tunali I, Milicevic Z, Koeneman L.   +7 more
europepmc   +1 more source

Cardiovascular Risk Reduction With Tirzepatide, a Dual GIP/GLP-1 Agonist, in Patients With Type 2 Diabetes Mellitus. [PDF]

J Lipid Atheroscler
Terui S, Minami T, Nakamura K, Terauchi Y.   +3 more
europepmc   +1 more source