Sulforaphane Attenuates Endometriosis in Rat Models Through Inhibiting PI3K/Akt Signaling Pathway
Dose-Response, 2019 Sulforaphane exerts anti-inflammatory activity in inflammatory diseases. The endometriosis (EM) is accompanied by chronic inflammation. The present study aims to explore the therapeutic effects of sulforaphane on EM and its underlying mechanism.
Aixiu Zhou, Yiting Hong, Yuchun Lv
doaj +1 more source
Multiple Antitumor Molecular Mechanisms Are Activated by a Fully Synthetic and Stabilized Pharmaceutical Product Delivering the Active Compound Sulforaphane (SFX-01) in Preclinical Model of Human Glioblastoma [PDF]
, 2021 Alessandro Colapietro +12 more
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Therapeutic Potential of Resveratrol in Cancer and Neurodegenerative Disorders: A Current Review
BioFactors, Volume 52, Issue 1, January/February 2026.Resveratrol induces the expressions of TP53, NRF2, and JDP2 axis in cancer cells to control ROS balance in mitochondria. The antioxidation responses were induced through SRIT1/3, HDAC, STAT3, TGFβ, and so on, to trigger the inflammation, and NFkB response to lead to the cell death of cancers or neuro‐damaged cells.
Kenly Wuputra +9 more
wiley +1 more source
Biopolymers, Volume 117, Issue 1, January 2026.ABSTRACT The effect of the enzyme‐mediated poly(gallic acid) (PGAL) as a potential redox regulator or redox activity compound (RAC) on the morphology of human neuroblastoma SH‐SY5Y cells and its methionine synthase (MS) activities is contrasted to those for disrupting compounds (EDC).
Gabriela García‐Cerón +7 more
wiley +1 more source
Accumulation of Dietary S-Methyl Cysteine Sulfoxide in Human Prostate Tissue [PDF]
, 2019 Scope: Observational studies have associated consumption of cruciferous vegetables with reduced risk of prostate cancer. This effect has been associated with the degradation products of glucosinolates—thioglycosides that accumulate within crucifers.
Ball, Richard Y. +11 more
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Effect of Ultrasound-Assisted Blanching on Myrosinase Activity and Sulforaphane Content in Broccoli Florets [PDF]
, 2020 Andrea Mahn +3 more
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Research Progress of Ferroptosis in Cerebral Infarction
Brain and Behavior, Volume 16, Issue 1, January 2026.Cerebral infarction triggers ischemia–reperfusion injury, leading to iron overload, oxidative stress, and mitochondrial dysfunction, which together initiate ferroptosis—an iron‐dependent, lipid peroxidation–driven form of neuronal death. Disruption of the System Xc−/GSH/GPX4 antioxidant axis and ACSL4‐mediated PUFA phospholipid enrichment accelerates ...
Yilan Fei, Qi Leng
wiley +1 more source
Sulforaphane Suppresses H2O2-Induced Oxidative Stress and Apoptosis via the Activation of AMPK/NFE2L2 Signaling Pathway in Goat Mammary Epithelial Cells [PDF]
, 2023 Dan Shao +7 more
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Food Frontiers, Volume 7, Issue 1, January 2026.The Notch signaling pathway plays a dual role in cancer, acting as both a tumor promoter and suppressor depending on cellular context. This review highlights how natural products modulate Notch signaling to inhibit tumor initiation, progression, angiogenesis, and cancer stem cell maintenance.
Rabab Fatima +15 more
wiley +1 more source
Archives of Medical Science, 2020 Introduction Sulforaphane is an active isothiocyanate and has been reported to exhibit many pharmacological and biological activities including anticancer activity.
Junshan Lin +3 more
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