Results 91 to 100 of about 16,993 (221)

WONOEP appraisal: Biomarkers and treatment strategies beyond the synapse

Epilepsia, Volume 67, Issue 10, Page 5026-5041, October 2026.
Abstract Epilepsy is a heterogeneous neurological disorder affecting more than 70 million people worldwide, posing significant challenges for clinicians due to its complex etiology, diverse manifestations, variable treatment responses, and the inability to predict seizures or disease onset reliably.
Mirte Scheper, Zining Liu, Aristea S. Galanopoulou, Gernot Hlauschek, Benjamin Sinclair, Wai Lam Leung, Stefanie Dedeurwaerdere, Elisabeth Doran, Solomon L. Moshé, David C. Henshall, Ozlem Akman, Pablo M. Casillas‐Espinosa   +11 more
wiley   +1 more source

Mechanisms of cell cycle arrest and apoptosis induction by sulforaphane and compinatorial effects of sulforaphane and 3,3'-Diindolylmethane on cancer cell growth inhibition [PDF]

, 2007
The chemopreventive isothiocyanate sulforaphane, which is derived from broccoli, was shown to induce a mitotic cell cycle arrest in the human colon cancer cell line 40-16. This arrest was followed by mitochondria-dependent apoptosis.
Pappa, Gerlinde
core  

Sulforaphane as a preventive agent in Oral Cancer- A Systematic Review

Oral Oncology Reports
Background: Cancer is one of the leading causes of death worldwide. Of these, oral cancer is the sixth most common malignancy. Several phytochemicals are emerging these days in prevention of oral cancer. Sulforaphane present in broccoli is one such agent
M. Parasakthi, Kavitha Sanjeev
doaj   +1 more source

Alveolar Macrophages: Development, Respiratory Homeostasis, Signal Pathways, Diseases, and Therapeutic Opportunities

MedComm, Volume 7, Issue 10, October 2026.
Alveolar macrophages: development, respiratory homeostasis, signal pathways, diseases, and therapeutic opportunities: During embryonic development, fetal progenitors migrate to the developing lungs via a CX3CR1‐dependent mechanism to establish the TrAM pool.
Sihan Yang, Ruomeng Li, Chuanjiang Yu, Jing Li, Xikun Zhou   +4 more
wiley   +1 more source

Transcriptome reveals the gene expression patterns of sulforaphane metabolism in broccoli florets - Fig 6

, 2019
Sulforaphane and glucoraphanin concentrations detected in different organs of broccoli at bolting stage (A). Chromatography of sulforaphane (C) and TIC Chromatograph of glucosinolate (B) corresponding to glucoraphanin spectrum (RT) (D).
Honghao Lv (800307), Mu Zhuang (537090), Yangyong Zhang (537091), Zhansheng Li (537088), Limei Yang (223781), Yumei Liu (286628), Lingyun Li (142918), Zhiyuan Fang (537089)   +7 more
core   +1 more source

Intratumoral Microbiota in Fueling Cancer and Steering Treatment Response

MedComm, Volume 7, Issue 10, October 2026.
Emerging research underscores the tumor‐specific colonization of microbiota and the role of intratumoral microbiota in cancer development and treatment resistance across multiple malignancies. Here, we provide a systematic review exploring the latest biotechnological advancements for studying low‐abundance intratumoral microbiota, their origins ...
Minhui Xu, Jie Yu, Ying Chen, Shengfang Ge, Lin Ye, Yefei Wang, Yixiong Zhou, Renbing Jia   +7 more
wiley   +1 more source

17β-Estradiol enhances sulforaphane cardioprotection against oxidative stress [PDF]

, 2017
The lower incidence of ischemic heart disease in female with respect to male gender suggests the possibility that female sex hormones could have specific effects in cardiovascular protection.
ANGELONI, Cristina, Falconi, M, HRELIA, SILVANA, Malaguti, M, Hrelia, S., MALAGUTI, MARCO, Teti, G, Barbalace, Mc, BARBALACE, MARIA CRISTINA, FALCONI, MIRELLA, Angeloni, C, TETI, GABRIELLA   +11 more
core   +1 more source

Novel Gram-Scale Production of Enantiopure R-Sulforaphane from Tuscan Black Kale Seeds

Molecules, 2014
Dietary R-sulforaphane is a highly potent inducer of the Keap1/Nrf2/ARE pathway. Furthermore, sulforaphane is currently being used in clinical trials to assess its effects against different tumour processes. This study reports an efficient preparation of
Gina Rosalinda De Nicola, Patrick Rollin, Emanuela Mazzon, Renato Iori   +3 more
doaj   +1 more source

Ischemic Stroke and Traumatic Brain Injury: Epidemiology, Molecular Pathways, and Emerging Therapies

MedComm, Volume 7, Issue 10, October 2026.
Schematic overview of secondary brain injury after ischemic stroke and traumatic brain injury. Both conditions trigger endothelial cell dysfunction, pericyte contraction, and upregulated AQP4 expression in astrocytic end‐feet, leading to blood–brain barrier disruption.
Mengzhao Feng, Qi Qin, Fang Wang, Kaiyuan Zhang, Zhihua Li, Junlei Chang, Min Yu, Fuyou Guo   +7 more
wiley   +1 more source

Transcriptome reveals the gene expression patterns of sulforaphane metabolism in broccoli florets.

PLoS ONE, 2019
Sulforaphane is a new and effective anti-cancer component that is abundant in broccoli. In the past few years, the patterns of variability in glucosinolate content and its regulation in A. thaliana have been described in detail. However, the diversity of
Zhansheng Li, Yumei Liu, Lingyun Li, Zhiyuan Fang, Limei Yang, Mu Zhuang, Yangyong Zhang, Honghao Lv   +7 more
doaj   +1 more source