Results 91 to 100 of about 11,962 (184)

Precision environmental medicine: Integrated multi‐exposure transcriptomics for shared molecular networks in COPD pathogenesis in response to environmental exposure

open access: yesPrecision Medical Sciences, Volume 15, Issue 2, Page 147-159, June 2026.
This integrated systems biology study of 2847 exposure‐related genes identifies a conserved 647‐gene core and CYP1B1 hub across cigarette smoke, ozone, and PM2.5. Three key pathways converge, enabling computational repurposing of 15 drug candidates (e.g., NRF2 activators) for environmentally induced COPD.
Fakher Rahim   +2 more
wiley   +1 more source

Investigating Sulforaphane’s anti-virulence and anti-quorum sensing properties against Pseudomonas aeruginosa

open access: yesFrontiers in Pharmacology
BackgroundP. aeruginosa, a significant bacterium, can cause severe illness and resistance to antibiotics. Quorum sensing (QS) systems regulate virulence factors production.
Mahmoud M. Bendary   +10 more
doaj   +1 more source

A Combined Colon Organoid‐Sensory Neuron Model Reveals Epithelial Contribution to Moringin Efficacy Against Painful Inflammatory Bowel Disease

open access: yesPhytotherapy Research, Volume 40, Issue 6, Page 3250-3266, June 2026.
Experimental workflow and main findings of the study. ABSTRACT Visceral pain is a major symptom of inflammatory bowel diseases (IBDs), requiring effective treatment strategies. Gut epithelium, beyond maintaining barrier integrity and microbiota homeostasis, modulates neurosensorial circuitries, influencing visceral sensitivity.
Francesco Margiotta   +7 more
wiley   +1 more source

Contents of sulforaphane and total isothiocyanates, antimutagenic activity, and inhibition of clastogenicity in pulp

open access: yesCzech Journal of Food Sciences, 2011
The consumption of Cruciferous vegetables is important for the prevention of cancerous diseases, particularly colorectal cancer. The effects of technological treatments (freezing, pasteurisation, high-pressure treatment) on the content of isothiocyanates,
Jiří Totušek   +9 more
doaj   +1 more source

Geraniol treatment enhances sulforaphane content through modulation of the glucosinolate biosynthetic pathway in kale (Brassica oleracea)

open access: yesApplied Biological Chemistry
Kale (Brassica oleracea) is a cruciferous vegetable known for health benefits, primarily due to sulforaphane, a compound with notable anticancer properties.
Jong-Moon Ju   +3 more
doaj   +1 more source

Optimization of the Extraction Process of Extract Containing Sulforaphane from Broccoli Seeds and Evaluation of Its Immunomodulatory Activity

open access: yesShipin gongye ke-ji
In order to investigate the optimal extraction process of sulforaphane from broccoli seeds and evaluate its immunomodulatory activity, broccoli seeds as the raw material, the effects of parameters including solid-liquid ratio, ethanol concentration ...
Wan TANG   +8 more
doaj   +1 more source

Research Progress on Anticancer Effects of Sulforaphane

open access: yesShipin gongye ke-ji
Cancer is the leading cause of mortality in human health, with the highest mortality rate among all diseases. Unfortunately, most of the current cancer treatments inevitably come with certain side effects.
Xinxin LIU   +4 more
doaj   +1 more source

Process Optimization and in Vitro Digestion Research of Raphanus sativus Seeds Sulforaphane Prepared by Enzymolysis Method

open access: yesShipin gongye ke-ji
The objective of this study was to investigate the optimal preparation process and digestive properties of sulforaphane from Raphanus sativus seeds prepared by enzymatic method.
Huilin LI   +6 more
doaj   +1 more source

Publication Only

open access: yes
HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

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