Results 81 to 90 of about 16,517 (209)
Chemical structure of sulforaphane (SFN).
, 2015 Chemical structure of sulforaphane (SFN).
Farzaneh Abassi Joozdani (747652) +3 more
core +1 more source
Prevention of Carcinogen-Induced Oral Cancer by Sulforaphane [PDF]
, 2016 Chronic exposure to carcinogens represents the major risk factor for head and neck squamous cell carcinoma (HNSCC). Beverages derived from broccoli sprout extracts (BSE) that are rich in glucoraphanin and its bioactive metabolite sulforaphane promote ...
Egner, Patricia A +10 more
core +1 more source
Experimental Physiology, EarlyView.Abstract (Poly)phenols are a diverse group of bioactive chemical compounds present in a wide range of plant‐ and animal‐based foods. Several thousands of (poly)phenols exist; many have potent biological effects, most notably antioxidant, anti‐inflammatory and vasodilatory.
Glyn Howatson, Tom Clifford
wiley +1 more source
Sulforaphane Attenuates Endometriosis in Rat Models Through Inhibiting PI3K/Akt Signaling Pathway
Dose-Response, 2019 Sulforaphane exerts anti-inflammatory activity in inflammatory diseases. The endometriosis (EM) is accompanied by chronic inflammation. The present study aims to explore the therapeutic effects of sulforaphane on EM and its underlying mechanism.
Aixiu Zhou, Yiting Hong, Yuchun Lv
doaj +1 more source
Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.1,25(OH)2D3 and dimethyl fumarate, administered alone or in combination, provide significant cardioprotection against isoproterenol‐induced myocardial injury by reducing oxidative stress, inflammation, and structural damage through modulation of the Nrf2/NF‐κB signaling pathways and the renin–angiotensin system (RAS).
Fatma Hande Karpuzoğlu +9 more
wiley +1 more source
Renal FailureObjective This study aimed to investigate the therapeutic effects of sulforaphane and the role of the Nrf2-Keap1/HO-1/ROS pathway in AngII-induced oxidative stress in podocyte injury.Methods Mouse mpc5 podocytes were divided into four groups: control ...
Wen Lu
doaj +1 more source
Novel Gram-Scale Production of Enantiopure R-Sulforaphane from Tuscan Black Kale Seeds
Molecules, 2014 Dietary R-sulforaphane is a highly potent inducer of the Keap1/Nrf2/ARE pathway. Furthermore, sulforaphane is currently being used in clinical trials to assess its effects against different tumour processes. This study reports an efficient preparation of
Gina Rosalinda De Nicola +3 more
doaj +1 more source
ChemistryOpen, Volume 15, Issue 9, September 2026.Integrated in silico discovery of thymoquinone analogs as potent Keap1 inhibitors for ALS therapy. Using validated QSAR, docking, and 200 ns MD simulations, we identified brain‐penetrant leads (CHEMBL3416163, CHEMBL4636830, and CHEMBL221598) with binding affinities up to fourfold stronger than thymoquinone, offering a targeted strategy to restore redox
Jabir C. Nalicho +3 more
wiley +1 more source
Sulforaphane as a preventive agent in Oral Cancer- A Systematic Review
Oral Oncology ReportsBackground: Cancer is one of the leading causes of death worldwide. Of these, oral cancer is the sixth most common malignancy. Several phytochemicals are emerging these days in prevention of oral cancer. Sulforaphane present in broccoli is one such agent
M. Parasakthi, Kavitha Sanjeev
doaj +1 more source
Microbiome–Driven Carcinogenesis and Circulating Microbial Signals in Genitourinary Cancers
Cancer Science, Volume 117, Issue 9, Page 2357-2365, September 2026.Experimental BBN models link gut microbial metabolism and diet‐microbiome interactions to urothelial carcinogenesis, while circulating extracellular vesicle‐associated bacterial DNA signals may reflect tumor immune contexture and immune checkpoint inhibitor outcomes in urothelial and renal cell carcinoma.
Atsunari Kawashima +12 more
wiley +1 more source