Results 61 to 70 of about 16,993 (221)

The Pharmaceutical Properties of Sulforaphane and Its Role in Tumor and Neurodegenerative Diseases

Shengwu huaxue yu shengwu wuli jinzhan
Sulforaphane is a naturally occurring active substance derived from cruciferous vegetables with potent antioxidant and anticancer properties. Researches have shown that sulforaphane has good bioavailability and can be absorbed by the small intestine ...
WU Jian-Le, LIU Xi-Jian, LIU Ru-Hua, JIANG Feng, MIAO Dan   +4 more
doaj   +1 more source

High-level and reusable preparation of sulforaphane by yeast cells expressing myrosinase

Food Chemistry: X, 2023
Myrosinase is a key tool for the fast and efficient preparation of sulforaphane which is one of the prominent natural ingredients found in brassicaceous vegetables.
Lili Wang, Hamed I. Hamouda, Yueyang Dong, Hong Jiang, Yongyi Quan, Yimiao Chen, Yan Liu, Jiaqi Wang, Mohamed A. Balah, Xiangzhao Mao   +9 more
doaj   +1 more source

Sulforaphane and ophthalmic diseases

Food Science & Nutrition
Abstract Sulforaphane (SFN) is an organosulfur compound categorized as an isothiocyanate (ITC), primarily extracted from cruciferous vegetables like broccoli and cabbage. The molecular formula of sulforaphane (SFN) is C 6 H 11 NOS
Yichi Zhang, Xiaojing Zhao, Yang Liu, Xiuxia Yang   +3 more
openaire   +2 more sources

Selective excitatory effects of γ‐glutamyl‐glycine, a glutathione metabolite, on GluN1 NMDA and mGlu5 receptors impacting synaptic plasticity

British Journal of Pharmacology, EarlyView.
Background and Purpose Gamma‐glutamyl dipeptides are essentially produced after glutathione (GSH) degradation. While several γ‐glutamyl dipeptides have been detected in different organs and body fluids, their biological activity remains elusive. This is the case for γ‐Glutamyl‐Glycine (γ‐Glu‐Gly) which has been found in different brain areas.
Sandro Andreu, Victoria Gizzi, Ugo Pasco, Fatiha Sebih, Yattou Zitouni, Pablo Jimenez, Valérie Rolland, Alain Chavanieu, Sébastien Estaran, Matthieu Rousset, Thierry Cens, Guillaume Cazals, Pierre Charnet, Janique Guiramand, Catherine Cohen‐Solal, Claudine Ménard, Marie‐Céleste de Jésus Ferreira, Nathalie Chevallier, Sonia Cantel, Michel Vignes, Julien Roussel   +20 more
wiley   +1 more source

Neuroprotective Effect of Sulforaphane against Methylglyoxal Cytotoxicity [PDF]

, 2015
Glycation, an endogenous process that leads to the production of advanced glycation end products (AGEs), plays a role in the etiopathogenesis of different neurodegenerative diseases, such as Alzheimer's disease (AD).
ANGELONI, Cristina, Malaguti, Marco, Barbalace, Maria Cristina, Hrelia, Silvana, Rizzo, Benedetta, Fabbri, Daniele   +5 more
core   +1 more source

Effects of lifelong sulforaphane intake on behavioural, neurochemical and biomolecular dysfunctions in the BTBR T+ Itpr3tf/J mouse model of autism spectrum disorders

British Journal of Pharmacology, EarlyView.
Created in BioRender. Schiavone, S. (2026). https://BioRender.com/cy0xq6z. Abstract Background and Purpose Autism spectrum disorders (ASD) are multifactorial neurodevelopmental conditions associated with oxidative stress and neuroinflammation across critical developmental periods.
Vladyslav Sikora, Maria Bove, Lisa Pia Agosti, Rossella Pia Palmieri, Mohsin Zafar, Paolo Tucci, Maria Grazia Morgese, Stefania Schiavone, Luigia Trabace   +8 more
wiley   +1 more source

Preclinical Efficacy and Involvement of AKT, mTOR, and ERK Kinases in the Mechanism of Sulforaphane against Endometrial Cancer

, 2020
Sulforaphane exerts anti-cancer activity against multiple cancer types. Our objective was to evaluate utility of sulforaphane for endometrial cancer therapy.
Doris Mangiaracina Benbrook, Rajani Rai, Kathleen Gong Essel, Yan Daniel Zhao, Vishal Chandra, Justin Garland   +5 more
core   +1 more source

BoMyrosinase plays an essential role in sulforaphane accumulation in response to selenite treatment in broccoli

Horticultural Plant Journal
Sulforaphane, a naturally specialized metabolite, plays significant roles in human disease prevention and plant defense. Myrosinase (MY) is a key gene responsible for the catalysis of sulforaphane formation, but the molecular mechanisms through which MY ...
Qiuyun Wu, Qi Wu, Yuxiao Tian, Chunyan Zhou, Shuxiang Mao, Junwei Wang, Ke Huang   +6 more
doaj   +1 more source

Storage in high-barrier pouches increases the sulforaphane concentration in broccoli florets. [PDF]

PLoS ONE, 2018
Sulforaphane is a phytochemical that is usually found in cruciferous vegetables and is known to have a depressive effect on gastric cancer. Preliminary investigations showed that the sulforaphane concentration in broccoli (Brassica oleracea var. italica)
Yoshio Makino, Yuto Nishimura, Seiichi Oshita, Takaharu Mizosoe, Takashi Akihiro   +4 more
doaj   +1 more source

Therapeutic effects of sulforaphane in ulcerative colitis: effect on antioxidant activity, mitochondrial biogenesis and DNA polymerization

Redox Report, 2022
Objectives Ulcerative colitis (UC), an inflammatory bowel disease, affects mucosal lining of colon leading to inflammation and ulcers. Sulforaphane is a natural compound obtained from cruciferous vegetables.
Abdullah Alattar, Reem Alshaman, Mohammed M. H. Al-Gayyar   +2 more
doaj   +1 more source