Results 41 to 50 of about 16,993 (221)
Frontiers in Cell and Developmental Biology, 2021 Broccoli-derived isothiocyanate sulforaphane inhibits inflammation and cancer. Sulforaphane may support healthy aging, but the underlying detailed mechanisms are unclear. We used the C. elegans nematode model to address this question.
Huihui Ji +9 more
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Sulforaphane protects against high cholesterol-induced mitochondrial bioenergetics impairments, inflammation, and oxidative stress and preserves pancreatic β-cells function [PDF]
, 2017 Cholesterol plays an important role in inducing pancreatic β-cell dysfunction, leading to an impaired insulin secretory response to glucose. This study aimed to determine the protective effects of sulforaphane, a natural isothiocyanate Nrf2-inducer ...
Carrasco-Pozo, Catalina +8 more
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Sulforaphane inhibits the Th2 immune response in ovalbumin-induced asthma [PDF]
BMB Reports, 2012 Sulforaphane (1-isothiocyanato-4-(methylsulfinyl)-butane), belongingto a family of natural compounds that are abundant in broccoli,has received significant therapeutic interest in recent years.However, the molecular basis of its effects remains to ...
Jun Ho Park +11 more
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Stability of sulforaphane for topical formulation [PDF]
Drug Development and Industrial Pharmacy, 2013 Sulforaphane (SFN) is a natural compound that has been investigated as a chemopreventive agent. SFN has been shown to inhibit the activator-protein-1 (AP-1) transcription factor and may be effective for inhibition of ultraviolet (UV) induced skin carcinogenesis.
Stephen J, Franklin +4 more
openaire +2 more sources
The neuroprotective mechanisms and effects of sulforaphane [PDF]
Brain Circulation, 2019 Sulforaphane (SFN) is a phytochemical found in cruciferous vegetables. It has been shown to have many protective effects against many diseases, including multiple types of cancer. SFN is a potent activator of the nuclear factor erythroid 2-related factor 2 (Nrf2) antioxidant response element (ARE) genetic pathway. Upregulation of Nrf2-ARE increases the
Eric A Klomparens, Yuchuan Ding
openaire +3 more sources
浙江大学学报. 农业与生命科学版, 2013 Sulforaphane (SFN) is an isothiocyanate (ITC) which exists as a precursor of glucosinolate (GS) in various cruciferous vegetables especially in broccoli. Sulforaphane has been regarded as a potential of anti-cancer agent derived from diet, mostly because
LI Baolong +5 more
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, 2019 Because of the demand for precision medicine, the investigatation on the application of carbon-dots-based nanosystems in the field of biomedicine is attracting more and more attention.
Xuewei Zhao (7027598) +13 more
core +1 more source
Sulforaphane - role in aging and neurodegeneration [PDF]
GeroScience, 2019 In the last several years, numerous molecules derived from plants and vegetables have been tested for their antioxidant, anti-inflammatory, and anti-aging properties. One of them is sulforaphane (SFN), an isothiocyanate present in cruciferous vegetables.
Santín-Márquez R. +4 more
openaire +3 more sources
Broccoli for the brain: a review of the neuroprotective mechanisms of sulforaphane
Frontiers in Cellular NeuroscienceSulforaphane, a phytochemical abundant in the sprouts of cruciferous vegetables, protects plants during a critical period of development. Through sulforaphane’s ability to activate the mammalian Nuclear Factor Erythroid 2-related Factor 2 (NRF2) pathway,
Riley N. Bessetti +3 more
doaj +1 more source
, 2023 A UHPLC-(ESI+)-MS/MS method was developed and validated for the simultaneous determination of glucoraphanin (GR), sulforaphane (SF), sulforaphane-glutathione (SF-GSH), sulforaphane-cysteine (SF-CYS), and sulforaphane-N-acetyl-cysteine (SF-NAC), in a ...
Angela Mastaloudis (16503351) +13 more
core +1 more source