Results 41 to 50 of about 16,517 (209)

Research Progress on Sulforaphane in the Prevention and Treatment of Nervous System Diseases [PDF]

Shipin Kexue, 2023
Sulforaphane is a natural product with excellent antioxidant and anti-inflammatory effects, which is ubiquitous in plants of the Brassicaceae family. The pathogenesis of nervous system diseases is complex, but many nervous system diseases are related to ...
SONG Xiaoye, PANG Xinyi, LU Yingjian
doaj   +1 more source

Anticancer activity of sulforaphane against human hepatoblastoma cells involves apoptosis, autophagy and inhibition of β-catenin signaling pathway

, 2020
Introduction Sulforaphane is an active isothiocyanate and has been reported to exhibit many pharmacological and biological activities including anticancer activity.
Junshan Lin, Yali Xu, Xing Zhao, Zhixin Qiu   +3 more
core   +1 more source

Sulforaphane Targets TRA-1/GLI Upstream of DAF-16/FOXO to Promote C. elegans Longevity and Healthspan

Frontiers in Cell and Developmental Biology, 2021
Broccoli-derived isothiocyanate sulforaphane inhibits inflammation and cancer. Sulforaphane may support healthy aging, but the underlying detailed mechanisms are unclear. We used the C. elegans nematode model to address this question.
Huihui Ji, Zhimin Qi, Daniel Schrapel, Monika Le, Yiqiao Luo, Bin Yan, Jury Gladkich, Michael Schaefer, Li Liu, Ingrid Herr   +9 more
doaj   +1 more source

Stability of sulforaphane for topical formulation [PDF]

Drug Development and Industrial Pharmacy, 2013
Sulforaphane (SFN) is a natural compound that has been investigated as a chemopreventive agent. SFN has been shown to inhibit the activator-protein-1 (AP-1) transcription factor and may be effective for inhibition of ultraviolet (UV) induced skin carcinogenesis.
Stephen J, Franklin, Sally E, Dickinson, Kelly L, Karlage, G T, Bowden, Paul B, Myrdal   +4 more
openaire   +2 more sources

The neuroprotective mechanisms and effects of sulforaphane [PDF]

Brain Circulation, 2019
Sulforaphane (SFN) is a phytochemical found in cruciferous vegetables. It has been shown to have many protective effects against many diseases, including multiple types of cancer. SFN is a potent activator of the nuclear factor erythroid 2-related factor 2 (Nrf2) antioxidant response element (ARE) genetic pathway. Upregulation of Nrf2-ARE increases the
Eric A Klomparens, Yuchuan Ding
openaire   +3 more sources

Sulforaphane induces glioprotection after LPS challenge

, 2022
Sulforaphane is a natural compound that presents anti-inflammatory and antioxidant properties, including in the central nervous system (CNS). Astroglial cells are involved in several functions to maintain brain homeostasis, actively participating in the ...
Goncalves, Carlos Alberto Saraiva, Bobermin, Larissa Daniele, Belló-Klein, Adriane, Wyse, Angela Terezinha de Souza, Weber, Fernanda Becker, Santos, Tiago Marcon dos, Quincozes-Santos, André   +6 more
core   +1 more source

Quantitative determination of sulforaphane from broccoli extract tablets and its role in the protection of acute liver injury induced by ethanol

浙江大学学报. 农业与生命科学版, 2013
Sulforaphane (SFN) is an isothiocyanate (ITC) which exists as a precursor of glucosinolate (GS) in various cruciferous vegetables especially in broccoli. Sulforaphane has been regarded as a potential of anti-cancer agent derived from diet, mostly because
LI Baolong, TIAN Sicong, TAN Jie, LI Bing, CHEN Jingyu, SHAN Yujuan   +5 more
doaj   +1 more source

Sulforaphane inhibits the Th2 immune response in ovalbumin-induced asthma [PDF]

BMB Reports, 2012
Sulforaphane (1-isothiocyanato-4-(methylsulfinyl)-butane), belongingto a family of natural compounds that are abundant in broccoli,has received significant therapeutic interest in recent years.However, the molecular basis of its effects remains to ...
Jun Ho Park, Jong Won Kim, Chang-Min Lee, Yeong Dae Kim, Sung Woon Chung, In Duk Jung, Kyung Tae Noh, Jin Wook Park, Deok Rim Heo, Yong Kyoo Shin, Jong Keun Seo, Yeong-Min Park   +11 more
doaj   +1 more source

Sulforaphane-Conjugated Carbon Dots: A Versatile Nanosystem for Targeted Imaging and Inhibition of EGFR-Overexpressing Cancer Cells

, 2019
Because of the demand for precision medicine, the investigatation on the application of carbon-dots-based nanosystems in the field of biomedicine is attracting more and more attention.
Xuewei Zhao (7027598), Xuewei Zhao, Wenjing Lu (429886), Chuan Dong, Wenjing Lu, Shaomin Shuang, Xinyan Tracy Cui, Lihong Shi (481066), Lihong Shi, Chuan Dong (1413937), Shaomin Shuang (1413946), Xinyan Tracy Cui (1309098), Fangfang Du, Fangfang Du (7027595)   +13 more
core   +1 more source

Sulforaphane - role in aging and neurodegeneration [PDF]

GeroScience, 2019
In the last several years, numerous molecules derived from plants and vegetables have been tested for their antioxidant, anti-inflammatory, and anti-aging properties. One of them is sulforaphane (SFN), an isothiocyanate present in cruciferous vegetables.
Santín-Márquez R., Alarcón-Aguilar A., López-Diazguerrero N.E., Königsberg M., Chondrogianni, Niki   +4 more
openaire   +3 more sources