Results 21 to 30 of about 16,517 (209)
Sulforaphane is anticonvulsant and improves mitochondrial function [PDF]
, 2015 The nuclear factor erythroid 2-related factor 2 pathway (Nrf2) has been previously identified to protect the brain against various impacts. Here, we investigated the effect of the Nrf2 activator sulforaphane in various seizure models and hippocampal ...
Carrasco-Pozo, Catalina +2 more
core +2 more sources
Stimulation of phagocytosis by sulforaphane [PDF]
Biochemical and Biophysical Research Communications, 2011 Sulforaphane, a major isothiocyanate derived from cruciferous vegetables, protects living systems against electrophile toxicity, oxidative stress, inflammation, and radiation. A major protective mechanism is the induction of a network of endogenous cytoprotective (phase 2) genes that are regulated by transcription factor Nrf2. To obtain a more detailed
Hiroyuki, Suganuma +4 more
openaire +2 more sources
Sulforaphane: A nutraceutical against diabetes-related complications [PDF]
, 2023 There is an increasing interest in the use of nutraceuticals and plant-derived bioactive compounds from foods for their potential health benefits. For example, as a major active ingredient found from cruciferous vegetables like broccoli, there has been ...
Tiano, Luca +11 more
core +3 more sources
The role of the host—Neutrophil biology
Periodontology 2000, EarlyView., 2023 Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
Ultrasonics Sonochemistry, 2022 In this investigation, the combinations of exogenous pretreatment (melatonin or vitamin C) and contact ultrasound-assisted air drying were utilized to dry broccoli florets. To understand the influences of the studied dehydration methods on the conversion
Beini Liu +6 more
doaj +1 more source
Ex vivo treatment of peripheral blood mononuclear cells (PBMC) with L-sulforaphane
, 2022 Blood samples were collected from healthy volunteers, PBMC were collected using standard ficoll centrifugation. RNA was collected from untreated and PBMC treated with 15 µM L-sulforaphane for 24 hours.
Tom Karagiannis (12036224) +2 more
core +1 more source
Food Science and Human Wellness, 2022 Innate immunity, particularly macrophages, is critical for intestinal homeostasis. Sulforaphane, a dietary isothiocyanate from cruciferous vegetables, has been reported to protect against intestinal inflammation.
Yuyang Sun +4 more
doaj +1 more source
Antileukemic activity of sulforaphane in primary blasts from patients affected by myelo- and lympho-proliferative disorders and in hypoxic conditions. [PDF]
PLoS ONE, 2014 Sulforaphane is a dietary isothiocyanate found in cruciferous vegetables showing antileukemic activity. With the purpose of extending the potential clinical impact of sulforaphane in the oncological field, we investigated the antileukemic effect of ...
Carmela Fimognari +8 more
doaj +1 more source
The Response to Sulforaphane in Metastatic Prostate Cancer Cells [PDF]
Sulforaphane is an isothiocyanate derived from cruciferous vegetables and has been under investigation as a cancer chemopreventive agent for over two decades.
Watson, Gregory
core +6 more sources
Monitoring Keap1-Nrf2 interactions in single live cells [PDF]
, 2014 The transcription factor NF-E2 p45-related factor 2 (Nrf2) and its negative regulator Kelch-like ECH associated protein 1 (Keap1) control the expression of nearly 500 genes with diverse cytoprotective functions.
Dinkova-Kostova, Albena, T +5 more
core +1 more source