Results 31 to 40 of about 16,993 (221)
The role of the host—Neutrophil biology
Periodontology 2000, EarlyView., 2023 Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
Ex vivo treatment of peripheral blood mononuclear cells (PBMC) with L-sulforaphane
, 2022 Blood samples were collected from healthy volunteers, PBMC were collected using standard ficoll centrifugation. RNA was collected from untreated and PBMC treated with 15 µM L-sulforaphane for 24 hours.
Tom Karagiannis (12036224) +2 more
core +1 more source
AMB Express, 2020 Sulforaphane (SFN) is a kind of natural isothiocyanate, which exists in cruciferous plants. Only few studies were about the anti-inflammatory effects of sulforaphane in ulcerative colitis.
Yan Zhang +5 more
doaj +1 more source
Efficacy of Sulforaphane in Neurodegenerative Diseases [PDF]
International Journal of Molecular Sciences, 2020 Sulforaphane (SFN) is a phytocompound belonging to the isothiocyanate family. Although it was also found in seeds and mature plants, SFN is mainly present in sprouts of many cruciferous vegetables, including cabbage, broccoli, cauliflower, and Brussels sprouts.
Schepici, Giovanni +2 more
openaire +2 more sources
Sulforaphanes: disruptors of phagophores and autolysosomes
Autophagy Reports, 2022 Sulforaphane and its metabolites (SFNs) cause apoptosis in cancers and could be potential anti-cancer drugs. We focused on investigating the underlying mechanisms through which SFNs inhibit cancers. First, SFNs cause microtubule disruption by phosphorylated MAPK1/ERK2-MAPK3/ERK1-mediated activation of 26S proteasome leading to a microtubule-associated ...
Yan Zhou, Wei Wu
openaire +3 more sources
Monitoring Keap1-Nrf2 interactions in single live cells [PDF]
, 2014 The transcription factor NF-E2 p45-related factor 2 (Nrf2) and its negative regulator Kelch-like ECH associated protein 1 (Keap1) control the expression of nearly 500 genes with diverse cytoprotective functions.
Dinkova-Kostova, Albena, T +4 more
core +1 more source
Use of sulforaphane in COVID-19:Clinical trials are needed
, 2022 We read with interest the narrative review authored by Kiser et al. (2021), which discussed extensively the antioxidant effect and anti-inflammatory effect of sulforaphane, a dietary supplement found in high amounts in cruciferous vegetables that is ...
Ramachandram, Dinesh Sangarran +5 more
core +1 more source
PLoS ONE, 2021 Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) is an important transcription factor that plays a pivotal role in cellular defense against oxidative injury.
Su-Jin Moon +7 more
doaj +1 more source
, 2020 Introduction Sulforaphane is an active isothiocyanate and has been reported to exhibit many pharmacological and biological activities including anticancer activity.
Junshan Lin +3 more
core +1 more source
Sulforaphane reduces obesity by reversing leptin resistance. [PDF]
, 2022 The ascending prevalence of obesity in recent decades is commonly associated with soaring morbidity and mortality rates, resulting in increased health-care costs and decreased quality of life.
Fadel, Amina +8 more
core +1 more source