Results 31 to 40 of about 11,962 (184)
The neuroprotective mechanisms and effects of sulforaphane [PDF]
Brain Circulation, 2019 Sulforaphane (SFN) is a phytochemical found in cruciferous vegetables. It has been shown to have many protective effects against many diseases, including multiple types of cancer. SFN is a potent activator of the nuclear factor erythroid 2-related factor 2 (Nrf2) antioxidant response element (ARE) genetic pathway. Upregulation of Nrf2-ARE increases the
Eric A Klomparens, Yuchuan Ding
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Horticulturae, 2021 The effects of storage conditions and cooking methods on chlorophyll, glucosinolate (GSL), and sulforaphane content in broccoli florets were investigated in this study.
Junwei Wang +8 more
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Research Progress on Sulforaphane in the Prevention and Treatment of Nervous System Diseases [PDF]
Shipin Kexue, 2023 Sulforaphane is a natural product with excellent antioxidant and anti-inflammatory effects, which is ubiquitous in plants of the Brassicaceae family. The pathogenesis of nervous system diseases is complex, but many nervous system diseases are related to ...
SONG Xiaoye, PANG Xinyi, LU Yingjian
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Natural Sulforaphane From Broccoli Seeds Against Influenza A Virus Replication in MDCK Cells
Natural Product Communications, 2019 We explored the potential application of sulforaphane against influenza A virus and elucidated the underlying cytopathic effect (CPE) and cytotoxicity. In the present study, 2 sulforaphane products were used to investigate the CPEs on influenza A virus ...
Zhansheng Li +6 more
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Chemopreventive activity of sulforaphane
Drug Design, Development and Therapy, 2018 Cancer is one of the major causes of morbidity and mortality in the world. Carcinogenesis is a multistep process induced by genetic and epigenetic changes that disrupt pathways controlling cell proliferation, apoptosis, differentiation, and senescence.
Xin Jiang +6 more
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Sulforaphane - role in aging and neurodegeneration [PDF]
GeroScience, 2019 In the last several years, numerous molecules derived from plants and vegetables have been tested for their antioxidant, anti-inflammatory, and anti-aging properties. One of them is sulforaphane (SFN), an isothiocyanate present in cruciferous vegetables.
Santín-Márquez R. +4 more
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Photothrombosis-induced infarction of the mouse cerebral cortex is not affected by the Nrf2-activator sulforaphane. [PDF]
PLoS ONE, 2012 Sulforaphane-induced activation of the transcription factor NF-E2 related factor 2 (Nrf2 or the gene Nfe2l2) and subsequent induction of the phase II antioxidant system has previously been shown to exert neuroprotective action in a transient model of ...
Michelle J Porritt +6 more
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Kinetics of sulforaphane in mice after consumption of sulforaphane‐enriched broccoli sprout preparation [PDF]
Molecular Nutrition & Food Research, 2013 ScopeSulforaphane (SF) is a natural isothiocyanate in broccoli sprouts with cancer chemopreventive activity. This study is aimed to use different methods to develop broccoli sprout preparations to compare their ability to deliver SF to the mice and to evaluate the kinetics and biodistribution of SF.Methods and resultsThe SF‐enriched sprout preparation ...
Li, Yanyan +5 more
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Journal of the Formosan Medical Association, 2017 Background/Purpose: Cancer stem cells (CSCs) are deemed as the driving force of tumorigenesis in oral squamous cell carcinomas (OSCCs). In this study, we investigated the chemotherapeutic effect of sulforaphane, a dietary component from broccoli sprouts,
Chia-Ming Liu +7 more
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PLoS ONE, 2021 Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) is an important transcription factor that plays a pivotal role in cellular defense against oxidative injury.
Su-Jin Moon +7 more
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