Results 31 to 40 of about 12,016 (182)

Sulforaphane inhibits the Th2 immune response in ovalbumin-induced asthma [PDF]

BMB Reports, 2012
Sulforaphane (1-isothiocyanato-4-(methylsulfinyl)-butane), belongingto a family of natural compounds that are abundant in broccoli,has received significant therapeutic interest in recent years.However, the molecular basis of its effects remains to ...
Jun Ho Park, Jong Won Kim, Chang-Min Lee, Yeong Dae Kim, Sung Woon Chung, In Duk Jung, Kyung Tae Noh, Jin Wook Park, Deok Rim Heo, Yong Kyoo Shin, Jong Keun Seo, Yeong-Min Park   +11 more
doaj   +1 more source

D, L-Sulforaphane Loaded Fe3O4@ Gold Core Shell Nanoparticles: A Potential Sulforaphane Delivery System. [PDF]

PLoS ONE, 2016
A novel design of gold-coated iron oxide nanoparticles was fabricated as a potential delivery system to improve the efficiency and stability of d, l-sulforaphane as an anticancer drug.
Hamidreza Kheiri Manjili, Leila Ma'mani, Sharareh Tavaddod, Maedeh Mashhadikhan, Abbas Shafiee, Hossein Naderi-Manesh   +5 more
doaj   +1 more source

Sulforaphane - role in aging and neurodegeneration [PDF]

GeroScience, 2019
In the last several years, numerous molecules derived from plants and vegetables have been tested for their antioxidant, anti-inflammatory, and anti-aging properties. One of them is sulforaphane (SFN), an isothiocyanate present in cruciferous vegetables.
Santín-Márquez R., Alarcón-Aguilar A., López-Diazguerrero N.E., Königsberg M., Chondrogianni, Niki   +4 more
openaire   +3 more sources

Broccoli for the brain: a review of the neuroprotective mechanisms of sulforaphane

Frontiers in Cellular Neuroscience
Sulforaphane, a phytochemical abundant in the sprouts of cruciferous vegetables, protects plants during a critical period of development. Through sulforaphane’s ability to activate the mammalian Nuclear Factor Erythroid 2-related Factor 2 (NRF2) pathway,
Riley N. Bessetti, Riley N. Bessetti, Karen A. Litwa, Karen A. Litwa   +3 more
doaj   +1 more source

Anticancer properties of sulforaphane: current insights at the molecular level

Frontiers in Oncology, 2023
Sulforaphane (SFN) is an isothiocyanate with multiple biomedical applications. Sulforaphane can be extracted from the plants of the genus Brassica. However, broccoli sprouts are the chief source of sulforaphane and are 20 to 50 times richer than mature ...
Muhammad Asif Ali, Noohela Khan, Nabeeha Kaleem, Waqas Ahmad, Salem Hussain Alharethi, Bandar Alharbi, Hassan H. Alhassan, Maher M. Al-Enazi, Ahmad Faizal Abdull Razis, Ahmad Faizal Abdull Razis, Babagana Modu, Babagana Modu, Daniela Calina, Javad Sharifi-Rad   +13 more
doaj   +1 more source

Kinetics of sulforaphane in mice after consumption of sulforaphane‐enriched broccoli sprout preparation [PDF]

Molecular Nutrition & Food Research, 2013
ScopeSulforaphane (SF) is a natural isothiocyanate in broccoli sprouts with cancer chemopreventive activity. This study is aimed to use different methods to develop broccoli sprout preparations to compare their ability to deliver SF to the mice and to evaluate the kinetics and biodistribution of SF.Methods and resultsThe SF‐enriched sprout preparation ...
Li, Yanyan, Zhang, Tao, Li, Xiaoqin, Zou, Peng, Schwartz, Steven J., Sun, Duxin   +5 more
openaire   +3 more sources

Exploring the anti‐inflammatory activity of sulforaphane

Immunology & Cell Biology, 2023
AbstractDysregulation of innate immune responses can result in chronic inflammatory conditions. Glucocorticoids, the current frontline therapy, are effective immunosuppressive drugs but come with a trade‐off of cumulative and serious side effects. Therefore, alternative drug options with improved safety profiles are urgently needed.
Katie Treasure, James Harris, Gary Williamson   +2 more
openaire   +3 more sources

Glucoraphanin conversion into sulforaphane and related compounds by gut microbiota

Frontiers in Physiology
Glucosinolate glucoraphanin, common in cruciferous vegetables, is a biologically stable precursor of isothiocyanates, such as sulforaphane and erucin, potent activators of Nrf2 signaling coordinating an adaptive response to oxidative stress. Sulforaphane
Tetiana R. Dmytriv, Tetiana R. Dmytriv, Oleh Lushchak, Oleh Lushchak, Volodymyr I. Lushchak, Volodymyr I. Lushchak   +5 more
doaj   +1 more source

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

BMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu, Xuejian Wang, Wenyan Jiang, Wan Hairul Anuar Kamaruddin, Chunyan Fang, Pengfei Zhang   +5 more
wiley   +1 more source

Sulforaphane and ophthalmic diseases

Food Science & Nutrition
Abstract Sulforaphane (SFN) is an organosulfur compound categorized as an isothiocyanate (ITC), primarily extracted from cruciferous vegetables like broccoli and cabbage. The molecular formula of sulforaphane (SFN) is C 6 H 11 NOS
Yichi Zhang, Xiaojing Zhao, Yang Liu, Xiuxia Yang   +3 more
openaire   +2 more sources