Results 51 to 60 of about 16,993 (221)

Kinetics of sulforaphane in mice after consumption of sulforaphane‐enriched broccoli sprout preparation [PDF]

Molecular Nutrition & Food Research, 2013
ScopeSulforaphane (SF) is a natural isothiocyanate in broccoli sprouts with cancer chemopreventive activity. This study is aimed to use different methods to develop broccoli sprout preparations to compare their ability to deliver SF to the mice and to evaluate the kinetics and biodistribution of SF.Methods and resultsThe SF‐enriched sprout preparation ...
Li, Yanyan, Zhang, Tao, Li, Xiaoqin, Zou, Peng, Schwartz, Steven J., Sun, Duxin   +5 more
openaire   +3 more sources

Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy

Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley   +1 more source

Sulforaphane-enriched extracts from glucoraphanin-rich broccoli exert antimicrobial activity against gut pathogens in vitro and innovative cooking methods increase in vivo intestinal delivery of sulforaphane [PDF]

, 2020
Purpose Studies on broccoli (Brassica oleracea var. italica) indicate beneficial effects against a range of chronic diseases, commonly attributed to their bioactive phytochemicals.
O’Connor, Gloria, Allwood, JW, Abukhabta, Salah, Gill, Chris I. R., Karatzas, Kimon Andreas, Rowland, Ian, Khalil Ghawi, Sameer, Lawther, Roger, Verrall, Susan, Pourshahidi, L. Kirsty, Lavery, Siobhan, Allwood, J. Will, O'Connor, Gloria, Latimer, Cheryl, Charalampopoulos, Dimitris, McDougall, Gordon, O’Connor, G., Ghawi, S.K., Pourshahidi, K., Charalampopoulos, D., Lavery, S., Gill, Chris IR; id_orcid, Latimer, C., Karatzas, K.A., O'Connor, G., Pourshahidi, L. Kirsty; id_orcid, McDougall, G., Gil, C.I.R., Allwood, J.W., Abukhabta, S,, Rowland, I., Verrall, S., Lawther, R.   +32 more
core   +1 more source

Chronic Prostatitis/Chronic Pelvic Pain Syndrome: Research Progress and Precision Diagnosis‐Therapy Under the Integrated Neuro–Immune–Metabolic–Microbiota Axis Framework

iMetaMed, EarlyView.
Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is increasingly recognized as a systemic disorder rather than a purely local prostate disease. The diagram illustrates the transition from the traditional local prostate‐centered model to a multi‐axis systemic framework involving clinical heterogeneity, local prostatic inflammation, systemic ...
Kun Wang, Jinfei Liu, Qiangsheng Wang, Lei Fan, Ziang Li, Xuexin Yu, Yonghao Chen, Xiaofan Lu, Guiyi Liao, Jialin Meng, Yu Guan   +10 more
wiley   +1 more source

Bioactive Natural Products in Cardiovascular Disease: Focus on Thrombotic Events

Phytotherapy Research, EarlyView.
An overview of the role of natural products (NP) in cardiovascular disease prevention, highlighting key mechanisms of action: including antiplatelet, antithrombotic, anti‐inflammatory, and antioxidant effects. Additionally, it illustrates the integration of diet–drug interactions, nutritional epigenetics, and the role of artificial intelligence in ...
Maria Nektaria Magkoulia, Despoina Pantazi   +1 more
wiley   +1 more source

Plant‐Derived Extracellular Vesicles: Biogenesis, Function, and Application in Cancer Immunotherapy

Phytotherapy Research, EarlyView.
This illustration shows the biogenesis pathways of edible and medicinal plant‐derived extracellular vesicles (PDEVs) and their therapeutic effects following uptake in the human body, highlighting their potential for application in cancer immunotherapy. ABSTRACT Plant‐derived extracellular vesicles (PDEVs) are nanoscale, lipid bilayer‐enclosed vesicles ...
Guosheng Li, Mengyu Li, Shujing Liu, Yuan Wei, Chen Wang   +4 more
wiley   +1 more source

Repeated Nrf2 stimulation using sulforaphane protects fibroblasts from ionizing radiation

, 2014
Most of the cytotoxicity induced by ionizing radiation is mediated by radical-induced DNA double-strand breaks. Cellular protection from free radicals can be stimulated several fold by sulforaphane-mediated activation of the transcription factor Nrf2 ...
Mathew, Sherin T,, Bergström, Petra,, Hammarsten, Ola,   +2 more
core   +1 more source

Cytotoxic and Antitumor Activity of Sulforaphane: The Role of Reactive Oxygen Species [PDF]

, 2015
According to recent estimates, cancer continues to remain the second leading cause of death and is becoming the leading one in old age. Failure and high systemic toxicity of conventional cancer therapies have accelerated the identification and ...
Carmela Fimognari, Piero Sestili, Fimognari, Carmela, SESTILI, PIERO   +3 more
core   +1 more source

Plant‐derived nanovesicles as potential drug delivery systems for topical use: Emerging applications in dermatology and cosmetology

VIEW, EarlyView.
Plant‐derived nanovesicles (PDNVs) are naturally secreted by fruit, vegetables, seeds, leaves and other natural sources. Used as drug delivery systems, they can combine intrinsic therapeutic activity, enhanced skin permeation and cargo‐carrying capacity, suitable for dermatological and cosmetic applications including hydration, antioxidant/anti ...
Dorotea Fiore, Beatrice Pellegrini, Antonia Mancuso, Maria Chiara Cristiano, Salvatore Panza, Donatella Paolino   +5 more
wiley   +1 more source

Chemical structure of sulforaphane (SFN).

, 2015
Chemical structure of sulforaphane (SFN).
Farzaneh Abassi Joozdani (747652), Shohreh Nafisi (489871), Faramarz Yari (747653), Parvaneh Abassi Joozdani (747654)   +3 more
core   +1 more source