Results 51 to 60 of about 16,517 (209)

Broccoli for the brain: a review of the neuroprotective mechanisms of sulforaphane

Frontiers in Cellular Neuroscience
Sulforaphane, a phytochemical abundant in the sprouts of cruciferous vegetables, protects plants during a critical period of development. Through sulforaphane’s ability to activate the mammalian Nuclear Factor Erythroid 2-related Factor 2 (NRF2) pathway,
Riley N. Bessetti, Riley N. Bessetti, Karen A. Litwa, Karen A. Litwa   +3 more
doaj   +1 more source

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

BMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu, Xuejian Wang, Wenyan Jiang, Wan Hairul Anuar Kamaruddin, Chunyan Fang, Pengfei Zhang   +5 more
wiley   +1 more source

Kinetics of sulforaphane in mice after consumption of sulforaphane‐enriched broccoli sprout preparation [PDF]

Molecular Nutrition & Food Research, 2013
ScopeSulforaphane (SF) is a natural isothiocyanate in broccoli sprouts with cancer chemopreventive activity. This study is aimed to use different methods to develop broccoli sprout preparations to compare their ability to deliver SF to the mice and to evaluate the kinetics and biodistribution of SF.Methods and resultsThe SF‐enriched sprout preparation ...
Li, Yanyan, Zhang, Tao, Li, Xiaoqin, Zou, Peng, Schwartz, Steven J., Sun, Duxin   +5 more
openaire   +3 more sources

WONOEP appraisal: Biomarkers and treatment strategies beyond the synapse

Epilepsia, EarlyView.
Abstract Epilepsy is a heterogeneous neurological disorder affecting more than 70 million people worldwide, posing significant challenges for clinicians due to its complex etiology, diverse manifestations, variable treatment responses, and the inability to predict seizures or disease onset reliably.
Mirte Scheper, Zining Liu, Aristea S. Galanopoulou, Gernot Hlauschek, Benjamin Sinclair, Wai Lam Leung, Stefanie Dedeurwaerdere, Elisabeth Doran, Solomon L. Moshé, David C. Henshall, Ozlem Akman, Pablo M. Casillas‐Espinosa   +11 more
wiley   +1 more source

Rewiring nutrition: Chemical insights into the physiological and microbiological roles of food's microconstituents

Food Biomacromolecules, EarlyView.
Bidirectional interactions between food‐derived sensory compounds, gut sensing and microbiota, host physiological feedback, and metabolite production within the food matrix collectively shape sensory perception, microbial dynamics, and metabolic health.
Mohammad Nazrul Islam Bhuiyan
wiley   +1 more source

Sulforaphane protects against high cholesterol-induced mitochondrial bioenergetics impairments, inflammation, and oxidative stress and preserves pancreatic β-cells function [PDF]

, 2017
Cholesterol plays an important role in inducing pancreatic β-cell dysfunction, leading to an impaired insulin secretory response to glucose. This study aimed to determine the protective effects of sulforaphane, a natural isothiocyanate Nrf2-inducer ...
Carrasco-Pozo, Catalina, Borges, Karin, Catalina Carrasco-Pozo, Carrasco Pozo, Catalina, Martin Gotteland, Karin Borges, Tan, Kah Ni, Gotteland, Martin, Kah Ni Tan   +8 more
core   +1 more source

The Pharmaceutical Properties of Sulforaphane and Its Role in Tumor and Neurodegenerative Diseases

Shengwu huaxue yu shengwu wuli jinzhan
Sulforaphane is a naturally occurring active substance derived from cruciferous vegetables with potent antioxidant and anticancer properties. Researches have shown that sulforaphane has good bioavailability and can be absorbed by the small intestine ...
WU Jian-Le, LIU Xi-Jian, LIU Ru-Hua, JIANG Feng, MIAO Dan   +4 more
doaj   +1 more source

Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy

Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley   +1 more source

Bioactive Natural Products in Cardiovascular Disease: Focus on Thrombotic Events

Phytotherapy Research, EarlyView.
An overview of the role of natural products (NP) in cardiovascular disease prevention, highlighting key mechanisms of action: including antiplatelet, antithrombotic, anti‐inflammatory, and antioxidant effects. Additionally, it illustrates the integration of diet–drug interactions, nutritional epigenetics, and the role of artificial intelligence in ...
Maria Nektaria Magkoulia, Despoina Pantazi   +1 more
wiley   +1 more source

High-level and reusable preparation of sulforaphane by yeast cells expressing myrosinase

Food Chemistry: X, 2023
Myrosinase is a key tool for the fast and efficient preparation of sulforaphane which is one of the prominent natural ingredients found in brassicaceous vegetables.
Lili Wang, Hamed I. Hamouda, Yueyang Dong, Hong Jiang, Yongyi Quan, Yimiao Chen, Yan Liu, Jiaqi Wang, Mohamed A. Balah, Xiangzhao Mao   +9 more
doaj   +1 more source