Results 11 to 20 of about 16,517 (209)
Chemopreventive activity of sulforaphane
Drug Design, Development and Therapy, 2018 Cancer is one of the major causes of morbidity and mortality in the world. Carcinogenesis is a multistep process induced by genetic and epigenetic changes that disrupt pathways controlling cell proliferation, apoptosis, differentiation, and senescence.
Xin Jiang +6 more
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D, L-Sulforaphane Loaded Fe3O4@ Gold Core Shell Nanoparticles: A Potential Sulforaphane Delivery System. [PDF]
PLoS ONE, 2016 A novel design of gold-coated iron oxide nanoparticles was fabricated as a potential delivery system to improve the efficiency and stability of d, l-sulforaphane as an anticancer drug.
Hamidreza Kheiri Manjili +5 more
doaj +3 more sources
Sulforaphane Target Protein Prediction: A Bioinformatics Analysis
Applied SciencesSulforaphane, a phytochemical found in cruciferous vegetables and various nutraceutical foods, plays a crucial role in promoting well-being and combating various diseases.
Francisco Alejandro Lagunas-Rangel
doaj +2 more sources
Measuring Sulforaphane and Its Metabolites in Human Plasma: A High Throughput Method [PDF]
Molecules, 2020 (1) Background: There is increasing understanding of the potential health benefits of cruciferous vegetables. In particular sulforaphane (SFN), found in broccoli, and its metabolites sulforaphane-glutathione (SFN-GSH), sulforaphane-cysteine (SFN-Cys ...
Annie Langston-Cox +5 more
doaj +2 more sources
Sulforaphane reduces obesity by reversing leptin resistance [PDF]
eLife, 2022 The ascending prevalence of obesity in recent decades is commonly associated with soaring morbidity and mortality rates, resulting in increased health-care costs and decreased quality of life.
Işın Çakır +8 more
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Exploring the anti‐inflammatory activity of sulforaphane
Immunology & Cell Biology, 2023 AbstractDysregulation of innate immune responses can result in chronic inflammatory conditions. Glucocorticoids, the current frontline therapy, are effective immunosuppressive drugs but come with a trade‐off of cumulative and serious side effects. Therefore, alternative drug options with improved safety profiles are urgently needed.
Katie Treasure +2 more
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Anticancer properties of sulforaphane: current insights at the molecular level
Frontiers in Oncology, 2023 Sulforaphane (SFN) is an isothiocyanate with multiple biomedical applications. Sulforaphane can be extracted from the plants of the genus Brassica. However, broccoli sprouts are the chief source of sulforaphane and are 20 to 50 times richer than mature ...
Muhammad Asif Ali +13 more
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Antileukemic Activity of Sulforaphane
, 2016 The biological complexity of cancer offers numerous targets for antineoplastic therapies. Diet is a common source of biologically active compounds. Many studies demonstrated an inverse relation between the consumption of vegetables and the risk of cancer.
CATANZARO, ELENA, FIMOGNARI, CARMELA
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Prevention of Myc-Driven Prostate Cancer in Mice by Oral Administration of Sulforaphane. [PDF]
Mol CarcinogABSTRACT Prevention is desirable to reduce suffering and death from prostate cancer. However, a clinical‐grade intervention for the prevention of this malignancy is still lacking. This study was undertaken to determine the feasibility of prostate cancer prevention by broccoli constituent sulforaphane (SFN) because epidemiological studies have suggested
Singh KB, Hahm ER, Jacobs BL, Singh SV.
europepmc +2 more sources
Inhibition of pancreatic cancer progression by sulforaphane-mediated downregulation of miR30a-3p and sulforaphane derivatives [PDF]
, 2021 PDA is one of the deadliest cancers with poor prognosis and profound therapy resistance, which is associated with the loss of gap junctional intercellular communication and Cx43 expression. A promising bioactive agent with multiple anti-cancer activities
Georgikou, Christina
core +1 more source