Results 111 to 120 of about 16,993 (221)
Prevention of Carcinogen-Induced Oral Cancer by Sulforaphane [PDF]
Chronic exposure to carcinogens represents the major risk factor for head and neck squamous cell carcinoma (HNSCC). Beverages derived from broccoli sprout extracts (BSE) that are rich in glucoraphanin and its bioactive metabolite sulforaphane promote ...
Egner, Patricia A +10 more
core +1 more source
In order to investigate the optimal extraction process of sulforaphane from broccoli seeds and evaluate its immunomodulatory activity, broccoli seeds as the raw material, the effects of parameters including solid-liquid ratio, ethanol concentration ...
Wan TANG +8 more
doaj +1 more source
Sulforaphane as a Promising Molecule for Fighting Cancer
Cancer is a complex disease characterized by multiple genetic and molecular alterations involving transformation, deregulation of apoptosis, proliferation, invasion, angiogenesis, and metastasis. To grow, invade, and metastasize, tumors need host components and primary dysfunction in the tumor microenvironment, in addition to cell dysfunction, can be ...
LENZI, MONIA +2 more
openaire +2 more sources
The molecular mechanism of sulforaphane on the induction of metallothionein (MT) genes in HepG2 cells and the antiproliferative effects of sulforaphane were investigated in this study.
Yeh, C.T., Yen, G.C., 顏國欽
core +1 more source
Kale (Brassica oleracea) is a cruciferous vegetable known for health benefits, primarily due to sulforaphane, a compound with notable anticancer properties.
Jong-Moon Ju +3 more
doaj +1 more source
Research Progress on Anticancer Effects of Sulforaphane
Cancer is the leading cause of mortality in human health, with the highest mortality rate among all diseases. Unfortunately, most of the current cancer treatments inevitably come with certain side effects.
Xinxin LIU +4 more
doaj +1 more source
Discovery of Sulforaphane as a Potent BACE1 Inhibitor Based on Kinetics and Computational Studies
BACE1 is the rate-limiting enzyme involved in the production and deposition of β-amyloid (Aβ). Since neurotoxic Aβ plays a critical role in Alzheimer’s disease (AD) pathogenesis, BACE1 has emerged as a key target for preventing AD ...
N Lee +13 more
core +1 more source
Thioredoxin reductases (TrxRs) catalyse the NADPH-dependent reduction of thioredoxin and play an important role in multiple cellular events related to carcinogenesis including cell proliferation, apoptosis and cell signaling.
Beckett, Geoffrey J. +10 more
core +1 more source
Background and Aim: Sulforaphane is a type of isothiocyanate with anticancer effects. In the present study, the effect of sulforaphane in angiogenesis in chicks' chorioallantoic membrane was investigated.
shahin shadiani +3 more
doaj

