Results 111 to 120 of about 16,993 (221)

Prevention of Carcinogen-Induced Oral Cancer by Sulforaphane [PDF]

open access: yes, 2016
Chronic exposure to carcinogens represents the major risk factor for head and neck squamous cell carcinoma (HNSCC). Beverages derived from broccoli sprout extracts (BSE) that are rich in glucoraphanin and its bioactive metabolite sulforaphane promote ...
Egner, Patricia A   +10 more
core   +1 more source

Optimization of the Extraction Process of Extract Containing Sulforaphane from Broccoli Seeds and Evaluation of Its Immunomodulatory Activity

open access: yesShipin gongye ke-ji
In order to investigate the optimal extraction process of sulforaphane from broccoli seeds and evaluate its immunomodulatory activity, broccoli seeds as the raw material, the effects of parameters including solid-liquid ratio, ethanol concentration ...
Wan TANG   +8 more
doaj   +1 more source

Sulforaphane as a Promising Molecule for Fighting Cancer

open access: yes, 2013
Cancer is a complex disease characterized by multiple genetic and molecular alterations involving transformation, deregulation of apoptosis, proliferation, invasion, angiogenesis, and metastasis. To grow, invade, and metastasize, tumors need host components and primary dysfunction in the tumor microenvironment, in addition to cell dysfunction, can be ...
LENZI, MONIA   +2 more
openaire   +2 more sources

Effect of sulforaphane on metallothionein expression and induction of apoptosis in human hepatoma HepG2 cells

open access: yes, 2014
The molecular mechanism of sulforaphane on the induction of metallothionein (MT) genes in HepG2 cells and the antiproliferative effects of sulforaphane were investigated in this study.
Yeh, C.T., Yen, G.C., 顏國欽
core   +1 more source

Geraniol treatment enhances sulforaphane content through modulation of the glucosinolate biosynthetic pathway in kale (Brassica oleracea)

open access: yesApplied Biological Chemistry
Kale (Brassica oleracea) is a cruciferous vegetable known for health benefits, primarily due to sulforaphane, a compound with notable anticancer properties.
Jong-Moon Ju   +3 more
doaj   +1 more source

Research Progress on Anticancer Effects of Sulforaphane

open access: yesShipin gongye ke-ji
Cancer is the leading cause of mortality in human health, with the highest mortality rate among all diseases. Unfortunately, most of the current cancer treatments inevitably come with certain side effects.
Xinxin LIU   +4 more
doaj   +1 more source

Discovery of Sulforaphane as a Potent BACE1 Inhibitor Based on Kinetics and Computational Studies

open access: yes, 2020
BACE1 is the rate-limiting enzyme involved in the production and deposition of β-amyloid (Aβ). Since neurotoxic Aβ plays a critical role in Alzheimer’s disease (AD) pathogenesis, BACE1 has emerged as a key target for preventing AD ...
N Lee   +13 more
core   +1 more source

Synergy between sulforaphane and selenium in the induction of thioredoxin reductase 1 requires both transcriptional and translational modulation

open access: yes, 2003
Thioredoxin reductases (TrxRs) catalyse the NADPH-dependent reduction of thioredoxin and play an important role in multiple cellular events related to carcinogenesis including cell proliferation, apoptosis and cell signaling.
Beckett, Geoffrey J.   +10 more
core   +1 more source

Investigating the effect of Sulforaphane on Angiogenesis in Chick’s Chorioallantoic membrane and its antioxidant activities

open access: yesمجله دانشگاه علوم پزشکی بیرجند, 2017
Background and Aim: Sulforaphane is a type of isothiocyanate with anticancer effects. In the present study, the effect of sulforaphane in angiogenesis in chicks' chorioallantoic membrane was investigated.
shahin shadiani   +3 more
doaj  

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