Prion degradation pathways: Potential for therapeutic intervention [PDF]
, 2015 Prion diseases are fatal neurodegenerative disorders. Pathology is closely linked to the misfolding of native cellular PrP(C) into the disease-associated form PrP(Sc) that accumulates in the brain as disease progresses. Although treatments have yet to be
Goold, R, McKinnon, C, Tabrizi, SJ
core +1 more source
Applied Biological ChemistryKale (Brassica oleracea) is a cruciferous vegetable known for health benefits, primarily due to sulforaphane, a compound with notable anticancer properties.
Jong-Moon Ju +3 more
doaj +1 more source
Investigation of Neuroprotective Effects of Sulforaphane and Allyl Isothiocyanate in an in vitro Alzheimer’s Disease Model [PDF]
, 2023 Fatma Hacet +3 more
openalex +1 more source
Research Progress on Anticancer Effects of Sulforaphane
Shipin gongye ke-jiCancer is the leading cause of mortality in human health, with the highest mortality rate among all diseases. Unfortunately, most of the current cancer treatments inevitably come with certain side effects.
Xinxin LIU +4 more
doaj +1 more source
Sulforaphane Prevents Hepatic Insulin Resistance by Blocking Serine Palmitoyltransferase 3-Mediated Ceramide Biosynthesis [PDF]
, 2019 Wendi Teng +5 more
openalex +1 more source
Sulforaphane Delays Fibroblast Senescence by Curbing Cellular Glucose Uptake, Increased Glycolysis, and Oxidative Damage [PDF]
, 2018 Florence Hariton +4 more
openalex +1 more source
Sulforaphane-Induced Cell Cycle Arrest and Senescence are accompanied by DNA Hypomethylation and Changes in microRNA Profile in Breast Cancer Cells [PDF]
, 2017 Anna Lewińska +3 more
openalex +1 more source
POTENTIAL USE OF SULFORAPHANE AS A NEUROPROTECTOR
, 2021 Sviatoslav A. Tsiumpala +2 more
openalex +2 more sources
Optimization of a Microencapsulation Process Using Oil-in-Water (O/W) Emulsion to Increase Thermal Stability of Sulforaphane [PDF]
, 2023 Víctor Zambrano +3 more
openalex +1 more source
Dietary bioactive compounds as histone deacetylase inhibitor for cancer prevention [PDF]
, 2012 Cancer is major disease causing worldwide human death which is related to different epigenetic dysregulation. One of the major dysregulation is overexpression of histone deacetylase (HDAC) including, HDAC1, HDAC4, HDAC6 and HDAC7. HDAC upregulation leads
Bhoi, Debadutta
core