Results 21 to 30 of about 21,198 (194)
Biomolecules, 2020 Cytosolic sulfotransferases (SULTs) catalyze phase II (conjugation) reactions of drugs and endogenous compounds. A complete set of recombinant fission yeast strains each expressing one of the 14 human SULTs was generated, including SULT4A1 and SULT6B1 ...
Yanan Sun +4 more
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Cholesterol sulfate in human physiology: what's it all about?
Journal of Lipid Research, 2003 Cholesterol sulfate is quantitatively the most important known sterol sulfate in human plasma, where it is present in a concentration that overlaps that of the other abundant circulating steroid sulfate, dehydroepiandrosterone (DHEA) sulfate.
Charles A. Strott, Yuko Higashi
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Structure and Function of Sulfotransferases [PDF]
Archives of Biochemistry and Biophysics, 2001 Sulfotransferases (STs) catalyze the transfer reaction of the sulfate group from the ubiquitous donor 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to an acceptor group of numerous substrates. This reaction, often referred to as sulfuryl transfer, sulfation, or sulfonation, is widely observed from bacteria to humans and plays a key role in various ...
Negishi, Masahiko +6 more
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Control of sulfur partitioning between primary and secondary metabolism in Arabidopsis
Frontiers in Plant Science, 2012 Sulfur is an essential nutrient for all organisms. Plants are able to take up inorganic sulfate and assimilate it into a range of bioorganic molecules either after reduction to sulfide or activation to 3’-phosphoadenosine 5’-phosphosulfate.
Stanislav eKopriva +5 more
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Multiplicity of Sulfotransferases
YAKUGAKU ZASSHI, 1997 Sulfation is an important conjugation reaction in the metabolism of a diversity of xenobiotics and endogenous compounds such as drugs, food additives, carcinogens, steroids and neurotransmitters. Sulfate conjugation is catalyzed by various kinds of sulfotransferase (ST) such as hydroxysteroid ST (HS-ST), phenol ST (P-ST) and estrogen ST (E-ST) present ...
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Journal of the Formosan Medical Association, 2014 Cigarette smoking is the main risk factor for urothelial carcinoma of the bladder (UCB). Glutathione S-transferase omega 1 (GSTO1) and sulfotransferase 1A1 (SULT1A1) have been reported to be associated with the metabolism of polycyclic aromatic ...
Min-Che Tung +7 more
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Molecules, 2016 The knowledge of processes in intestinal cells is essential, as most xenobiotics come into contact with the small intestine first. Caco-2 cells are human colorectal adenocarcinoma that once differentiated, exhibit enterocyte-like characteristics.
Kateřina Lněničková +6 more
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UPLC–MS/MS Identification of Sterol Sulfates in Marine Diatoms
Marine Drugs, 2018 Diatoms are unicellular eukaryotic organisms that play a key ecological and biogeochemical role in oceans as major primary producers. Recently, these microalgae have also attracted interest as a promising source of functional products with widespread ...
Genoveffa Nuzzo +10 more
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Frontiers in Cell and Developmental Biology, 2020 Heparan sulfate (HS) is a glycosaminoglycan found mainly in its protein-conjugated form at the cell surface and the extracellular matrix. Its high sulfation degree mediates functional interactions with positively charged amino acids in proteins.
Felipe C. O. B. Teixeira +11 more
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Advanced Science, EarlyView.By integrating 516 whole‐genome resequencing datasets and 236 transcriptomes of allotetraploid common carp, this study establishes the first population‐scale atlas of transposable element (TE) variation in teleost species. TE bursts, relaxed purifying selection, and lineage‐specific loss of ancient insertions shape genome evolution and phenotypic ...
Shuimu Hu +11 more
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