Results 21 to 30 of about 20,368 (201)

Minoxidil in trichological practice

Медицинский совет, 2018
Management of patients with alopecia is still a challenging task. Minoxidil is a pyrimidine derivative, a potent KATP channel opener, and has been shown to act as a vasodilating agent.
O. Yu. Olisova, I. P. Gostroverkhova
doaj   +1 more source

Investigation and Computational Analysis of the Sulfotransferase (SOT) Gene Family in Potato (Solanum tuberosum): Insights into Sulfur Adjustment for Proper Development and Stimuli Responses

Plants, 2021
Various kinds of primary metabolisms in plants are modulated through sulfate metabolism, and sulfotransferases (SOTs), which are engaged in sulfur metabolism, catalyze sulfonation reactions.
Sahar Faraji, Parviz Heidari, Hoorieh Amouei, Ertugrul Filiz, Abdullah, Peter Poczai   +5 more
doaj   +1 more source

Surface Effect of Assembling Enzyme and Modulation of Surface Enzyme Activity with Electric Potential Stress

International Journal of Electrochemical Science, 2012
The fluorescent marker of rhodamine B amine is successfully used to evaluate the immobilization capability onto silicon-based patterns fabricated by semiconductor manufacturing.
Cheng-Han Chao, Kun-Lin Li, Chung-Shu Wu, Cheng-Che Lee, Han-Ping Chiang, Yuh-Shyong Yang, Tung-Ming Pan, Fu-Hsiang Ko   +7 more
doaj   +1 more source

Design and Engineering of an Artificial Bifunctional N‐Deacetylase/N‐Sulfotransferase for the Biosynthesis of N‐Sulfated Heparosan

Advanced Science, EarlyView.
An artificial bifunctional N‐deacetylase/N‐sulfotransferase was engineered in Escherichia coli by combining screened N‐deacetylases with an NST domain. The integrated engineering strategy improved enzyme performance. The optimized enzyme efficiently converted heparosan into N‐sulfated heparosan, addressing a key bottleneck in microbial heparin ...
Xintong Xi, Ruirui Xu, Daoan Wang, Guobin Yin, Xinjing Wang, Haiqin Chen, Guocheng Du, Jian Chen, Zhen Kang   +8 more
wiley   +1 more source

Identification of Catalposide Metabolites in Human Liver and Intestinal Preparations and Characterization of the Relevant Sulfotransferase, UDP-glucuronosyltransferase, and Carboxylesterase Enzymes

Pharmaceutics, 2019
Catalposide, an active component of Veronica species such as Catalpa ovata and Pseudolysimachion lingifolium, exhibits anti-inflammatory, antinociceptic, anti-oxidant, hepatoprotective, and cytostatic activities.
Deok-Kyu Hwang, Ju-Hyun Kim, Yongho Shin, Won-Gu Choi, Sunjoo Kim, Yong-Yeon Cho, Joo Young Lee, Han Chang Kang, Hye Suk Lee   +8 more
doaj   +1 more source

Functional Expression of All Human Sulfotransferases in Fission Yeast, Assay Development, and Structural Models for Isoforms SULT4A1 and SULT6B1

Biomolecules, 2020
Cytosolic sulfotransferases (SULTs) catalyze phase II (conjugation) reactions of drugs and endogenous compounds. A complete set of recombinant fission yeast strains each expressing one of the 14 human SULTs was generated, including SULT4A1 and SULT6B1 ...
Yanan Sun, David Machalz, Gerhard Wolber, Maria Kristina Parr, Matthias Bureik   +4 more
doaj   +1 more source

Engineering sulfonate group donor regeneration systems to boost biosynthesis of sulfated compounds

Nature Communications, 2023
Sulfonation as one of the most important modification reactions in nature is essential for many biological macromolecules to function. Development of green sulfonate group donor regeneration systems to efficiently sulfonate compounds of interest is ...
Ruirui Xu, Weijao Zhang, Xintong Xi, Jiamin Chen, Yang Wang, Guocheng Du, Jianghua Li, Jian Chen, Zhen Kang   +8 more
doaj   +1 more source

Multiplicity of Sulfotransferases

YAKUGAKU ZASSHI, 1997
Sulfation is an important conjugation reaction in the metabolism of a diversity of xenobiotics and endogenous compounds such as drugs, food additives, carcinogens, steroids and neurotransmitters. Sulfate conjugation is catalyzed by various kinds of sulfotransferase (ST) such as hydroxysteroid ST (HS-ST), phenol ST (P-ST) and estrogen ST (E-ST) present ...
openaire   +3 more sources

Cholesterol Sulfate: Pathophysiological Implications and Potential Therapeutics

Biomolecules
Cholesterol sulfate (CS) is a naturally occurring cholesterol derivative that is widely distributed across various tissues and body fluids. In humans, its biosynthesis is primarily mediated by the sulfotransferase (SULT) 2B1b (SULT2B1b).
Xiaoqian Yu, Siman Lei, Ying Shen, Tao Liu, Jun Li, Jia Wang, Zhiguang Su   +6 more
doaj   +1 more source

Cholesterol sulfate in human physiology: what's it all about?

Journal of Lipid Research, 2003
Cholesterol sulfate is quantitatively the most important known sterol sulfate in human plasma, where it is present in a concentration that overlaps that of the other abundant circulating steroid sulfate, dehydroepiandrosterone (DHEA) sulfate.
Charles A. Strott, Yuko Higashi
doaj   +1 more source