Results 31 to 40 of about 434,720 (340)

Ndufaf2, a protein in mitochondrial complex I, interacts in vivo with methionine sulfoxide reductases

Redox Report, 2023
Background Methionine sulfoxide reductases are found in all aerobic organisms. They function in antioxidant defense, cellular regulation by reversible oxidation of methionine in proteins, and in protein structure.
Sujin Park, José A. Trujillo-Hernandez, Rodney L. Levine   +2 more
doaj   +1 more source

Factors associated with variation in single-dose albendazole pharmacokinetics: A systematic review and modelling analysis.

PLoS Neglected Tropical Diseases, 2022
BackgroundAlbendazole is an orally administered anti-parasitic medication with widespread usage in a variety of both programmatic and clinical contexts.
Charles Whittaker, Cédric B Chesnais, Sébastien D S Pion, Joseph Kamgno, Martin Walker, Maria-Gloria Basáñez, Michel Boussinesq   +6 more
doaj   +1 more source

Injectable polypeptide hydrogels via methionine modification for neural stem cell delivery. [PDF]

, 2018
Injectable hydrogels with tunable physiochemical and biological properties are potential tools for improving neural stem/progenitor cell (NSPC) transplantation to treat central nervous system (CNS) injury and disease.
Czechanski, A, Deming, TJ, Kim, JH, O'Shea, TM, Reinholdt, LG, Sofroniew, MV, Wollenberg, AL   +6 more
core   +1 more source

Transfer of electrophilic NH using convenient sources of ammonia: direct synthesis of N–H sulfoximines from sulfoxides [PDF]

, 2016
The transfer of nitrogen atoms is extremely valuable in the preparation of medicinal compounds. Here, a new system for NH transfer is developed to prepare sulfoximines, which are emerging as valuable motifs for drug discovery.
Bentley, Bizet, Bizet, Buglioni, Carroccia, Cheng, Collins, Collins, Collins, Dauban, Degennaro, Dohi, Dong, Fiori, Goldberg, Gutmann, Iacobucci, Ivanov, Jat, Johnson, Langner, Lücking, Lücking, Mancheño, Mendiola, Miao, Miyasaka, Ochiai, Okamura, Rit, Roizen, Romero, Shen, Silva, Souto, Starkov, Tamura, Teng, Wang, Weber, Williamson, Zenzola, Zhu, Zou   +43 more
core   +1 more source

Crosstalk of TNF-α, IFN-γ, NF-kB, STAT1 and redox signaling in lipopolysaccharide/d-galactosamine/dimethylsulfoxide-induced fulminant hepatic failure in mice

Saudi Pharmaceutical Journal, 2023
Purpose: The clinical study of fulminant hepatic failure is challenging due to its high mortality and relative rarity, necessitating reliance on pre-clinical models to gain insight into its pathophysiology and develop potential therapies.
Abdulrazaq Alanazi, Mahmoud N. Nagi, Dhafer Y. Alhareth, Mohammed A Al-Hamamah, Mohamed A Mahmoud, Sheikh F. Ahmad, Mushtaq A. Ansari, Ahmed Nadeem, Saleh A. Bakheet, Gamaleldin I. Harisa, Sabry M. Attia   +10 more
doaj   +1 more source

A dog model for acetaminophen-induced fulminant hepatic failure. [PDF]

, 1989
The development of a large animal model of fulminant hepatic failure produced with acetaminophen that should be useful in the development and evaluation of potential medical therapies for the important clinical problem of fulminant hepatic failure is ...
Barone, M, Demetris, J, Francavilla, A, Makowka, L, Polimeno, L, Prelich, J, Starzl, TE, Van Thiel, DH   +7 more
core   +1 more source

Crystal structures of polymerized lithium chloride and dimethyl sulfoxide in the form of {2LiCl·3DMSO}n and {LiCl·DMSO}n

Acta Crystallographica Section E: Crystallographic Communications, 2023
Two novel LiCl·DMSO polymer structures were created by combining dry LiCl salt with dimethyl sulfoxide (DMSO), namely, catena-poly[[chloridolithium(I)]-μ-(dimethyl sulfoxide)-κ2O:O-[chloridolithium(I)]-di-μ-(dimethyl sulfoxide)-κ4O:O], [Li2Cl2(C2H6OS)3]n,
Nichole R. Valdez, David J. Herman, Martin B. Nemer, Mark A. Rodriguez, Eric Allcorn   +4 more
doaj   +1 more source

Stepped vitrification technique for human ovarian tissue cryopreservation [PDF]

, 2019
The advantage of stepped vitrification (SV) is avoiding ice crystal nucleation, while decreasing the toxic effects of high cryoprotectant concentrations. We aimed to test this method for human ovarian tissue cryopreservation.
Amorin, C.A., Camboni, A., Corral, A., Dolmans, M.M., Kilbride, P., Leonel, E.C.R., Morris, John G., Risco, Ramón, Taboga, S.R., Vázquez, Marina   +9 more
core   +1 more source

Sulfoxides

, 2014
Citation: 'sulfoxides' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.S06124 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
null Anna, George Wypych
openaire   +2 more sources

Design, Synthesis and Preliminary Biological Evaluation of Novel Benzyl Sulfoxide 2-Indolinone Derivatives as Anticancer Agents

Molecules, 2017
In this work, a series of novel benzyl sulfoxide 2-indolinone derivatives was designed and synthesized as potent anticancer agents. Tyrosine kinase inhibitory activity assay indicated that most of the compounds showed significant activity.
Lin Tang, Tao Peng, Gang Wang, Xiaoxue Wen, Yunbo Sun, Shouguo Zhang, Shuchen Liu, Lin Wang   +7 more
doaj   +1 more source