Results 31 to 40 of about 322,242 (344)

Fast and Selective Post-polymerization Modification of Conjugated Polymers Using Dimethyldioxirane

Frontiers in Chemistry, 2019
Modification of functional groups attached to conjugated polymer backbones can drastically alter the material properties. Oxidation of electron-donating thioalkyl substituents to electron-withdrawing sulfoxides or sulfones is a particularly effective ...
Emmanuel Reichsöllner, Adam Creamer, Shengyu Cong, Abby Casey, Simon Eder, Martin Heeney, Florian Glöcklhofer, Florian Glöcklhofer   +7 more
doaj   +1 more source

Factors associated with variation in single-dose albendazole pharmacokinetics: A systematic review and modelling analysis.

PLoS Neglected Tropical Diseases, 2022
BackgroundAlbendazole is an orally administered anti-parasitic medication with widespread usage in a variety of both programmatic and clinical contexts.
Charles Whittaker, Cédric B Chesnais, Sébastien D S Pion, Joseph Kamgno, Martin Walker, Maria-Gloria Basáñez, Michel Boussinesq   +6 more
doaj   +1 more source

Crosstalk of TNF-α, IFN-γ, NF-kB, STAT1 and redox signaling in lipopolysaccharide/d-galactosamine/dimethylsulfoxide-induced fulminant hepatic failure in mice

Saudi Pharmaceutical Journal, 2023
Purpose: The clinical study of fulminant hepatic failure is challenging due to its high mortality and relative rarity, necessitating reliance on pre-clinical models to gain insight into its pathophysiology and develop potential therapies.
Abdulrazaq Alanazi, Mahmoud N. Nagi, Dhafer Y. Alhareth, Mohammed A Al-Hamamah, Mohamed A Mahmoud, Sheikh F. Ahmad, Mushtaq A. Ansari, Ahmed Nadeem, Saleh A. Bakheet, Gamaleldin I. Harisa, Sabry M. Attia   +10 more
doaj   +1 more source

Physiological Roles of Plant Methionine Sulfoxide Reductases in Redox Homeostasis and Signaling

Antioxidants, 2018
Oxidation of methionine (Met) leads to the formation of two S- and R-diastereoisomers of Met sulfoxide (MetO) that are reduced back to Met by methionine sulfoxide reductases (MSRs), A and B, respectively.
P. Rey, L. Tarrago
semanticscholar   +1 more source

Continuous Bioinspired Oxidation of Sulfides

Molecules, 2020
A simple, efficient, and selective oxidation under flow conditions of sulfides into their corresponding sulfoxides and sulfones is reported herein, using as a catalyst perselenic acid generated in situ by the oxidation of selenium (IV) oxide in a diluted
Francesca Mangiavacchi, Letizia Crociani, Luca Sancineto, Francesca Marini, Claudio Santi   +4 more
doaj   +1 more source

Crystal structures of polymerized lithium chloride and dimethyl sulfoxide in the form of {2LiCl·3DMSO}n and {LiCl·DMSO}n

Acta Crystallographica Section E: Crystallographic Communications, 2023
Two novel LiCl·DMSO polymer structures were created by combining dry LiCl salt with dimethyl sulfoxide (DMSO), namely, catena-poly[[chloridolithium(I)]-μ-(dimethyl sulfoxide)-κ2O:O-[chloridolithium(I)]-di-μ-(dimethyl sulfoxide)-κ4O:O], [Li2Cl2(C2H6OS)3]n,
Nichole R. Valdez, David J. Herman, Martin B. Nemer, Mark A. Rodriguez, Eric Allcorn   +4 more
doaj   +1 more source

The Excretion Period of Triclabendazole Residual and it's Metabolites after Triclafascid Application on Sheep

Российский паразитологический журнал, 2019
The purpose of the research: studying the excretion period of triclabendazole residual and its metabolites after triclafascid application on productive animals. Materials and methods. Researches were carried out on 12 sheep of Romanov breed at the age of
M. B. Musaev, I. E. Shumakovich, M. S. Khalikov, N. B. Emelyanova, P. P. Kochetkov, N. E. Patyukov, V. E. Abramov   +6 more
doaj   +1 more source

DETERMINATION OF FENBENDAZOLE AND ITS METABOLITES IN MILK BY THE METHOD OF LIQUID CHROMATOGRAPHY COUPLED WITH TANDEM MASS SPECTROMETRY

Российский паразитологический журнал, 2016
Objective of research: Development of methods for the determination of fenbendazole and its metabolites in milk by liquid chromatography coupled with tandem mass spectrometry.Materials and methods: Fenbendazole was administered orally to five cows ...
P. P. Kochetkov, A. I. Varlamova, V. E. Abramov, N. S. Misura, E. V. Abramova, S. B. Abramov, N. I. Koshevarov, I. A. Arkhipov   +7 more
doaj   +1 more source

Sulfoxide Reductases and Applications in Biocatalytic Preparation of Chiral Sulfoxides: A Mini-Review

Frontiers in Chemistry, 2021
Chiral sulfoxides are valuable organosulfur compounds that have been widely used in medicinal and organic synthesis. Biocatalytic approaches for preparing chiral sulfoxides were developed in the past few years, mainly through asymmetric oxidation of ...
Tao Peng, Xiaoling Cheng, Yongzheng Chen, Jiawei Yang, Jiawei Yang   +4 more
doaj   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source