Results 291 to 300 of about 33,864 (335)

Affinity‐Based Isolation and One‐Pot Analysis of Extracellular Vesicles from Biofluids Using Phase Separated Zwitterionic Coacervates

Advanced Science, EarlyView.
This study presents a novel method for affinity‐based isolation and analysis of extracellular vesicles from biofluids using phase‐separated zwitterionic coacervates functionalized with a membrane‐sensing peptide. This technology minimizes nonspecific binding, enabling high‐yield isolation and direct one‐pot biomarker profiling.
Francesca Torrini, Roberto Frigerio, Jonathan Garlipp, Philippe Lenzen, Karl Normak, Carolina Paganini, Marina Cretich, Alessandro Gori, Paolo Arosio   +8 more
wiley   +1 more source

Stereodivergent Synthesis of 1,4-Dicarbonyl Compounds through Sulfonium Rearrangement: Mechanistic Investigation, Stereocontrolled Access to γ-Lactones and γ-Lactams, and Total Synthesis of Paraconic Acids. [PDF]

J Am Chem Soc
G-Simonian N, Spieß P, Riomet M, Maryasin B, Klose I, Beaton Garcia A, Pollesböck L, Kaldre D, Todorovic U, Minghua Liu J, Kaiser D, González L, Maulide N.   +12 more
europepmc   +1 more source

The Rise of Chalcohalide Solar Cells: Comprehensive Insights From Materials to Devices

Advanced Science, EarlyView.
This review provides a detailed overview of recent advancements in chalcohalide solar cells, focusing on structure design, material chemistry, synthesis methods, and device optimization. It also highlights future directions for improving device efficiency through innovative device architectures and synthesis techniques, addressing key challenges in ...
Hongrui Zhang, Yiming Xia, Yangfan Zhang, Uma V. Ghorpade, Mingrui He, Seung Wook Shin, Xiaojing Hao, Mahesh P. Suryawanshi   +7 more
wiley   +1 more source

Chiral Thianthrenes. [PDF]

Int J Mol Sci
Plater MJ, Harrison WTA.
europepmc   +1 more source

Role of Testosterone Signaling in Microglia: A Potential Role for Sex‐Related Differences in Alzheimer's Disease

Advanced Science, EarlyView.
Testosterone enhances Aβ‐induced autophagy in microglia via the non‐genomic testosterone receptor GPRC6A, promoting Aβ clearance by suppressing ERK phosphorylation and inhibiting mTOR activation. In male 5xFAD mice, testicular removal reduces microglial autophagy and Aβ clearance, which is restored by testosterone.
Haiyan Du, Akiko Mizokami, Junjun Ni, Simeng Zhang, Yosuke Yamawaki, Tomomi Sano, Eijiro Jimi, Isei Tanida, Takashi Kanematsu   +8 more
wiley   +1 more source

Magnetic nano-sized solid acid catalyst bearing sulfonic acid groups for biodiesel synthesis and oxidation of sulfides. [PDF]

Sci Rep
Singh D, Singh K, Jadeja Y, Menon SV, Singh P, Ibrahim SM, Singh M, Abosaoda MK, Al Reshaidan SB, El-Meligy MA.   +9 more
europepmc   +1 more source

Massage‐Mimicking Nanosheets Mechanically Reorganize Inter‐organelle Contacts to Restore Mitochondrial Functions in Parkinson's Disease

Advanced Science, EarlyView.
Parkinson's disease (PD) progression is aggravated by disrupted inter‐organelle contacts, which are influenced by mechanical forces. NanoMassage, 200 nm PEGylated black phosphorus nanosheets, deliver targeted mechanical stimulation to neural cells.
Tianqi Li, Liwen Huang, Chenxiao Guo, Jing Ren, Xi Chen, Yachu Ke, Zengyu Xun, Wenzhuo Hu, Yilin Qi, Heping Wang, Zhongying Gong, Xing‐Jie Liang, Xue Xue   +12 more
wiley   +1 more source

In situ decorated pd NPs on Triazin-encapsulated Fe₃O₄/SiO₂-NH₂ as magnetic catalyst for the synthesis of diaryl ethers and oxidation of sulfides. [PDF]

Sci Rep
Singh D, Singh K, Sharma P, Jadeja Y, Mgm J, Singh P, Kaur K, Atif M, El-Meligy MA, Husseen B.   +9 more
europepmc   +1 more source

UGDH Lactylation Aggravates Osteoarthritis by Suppressing Glycosaminoglycan Synthesis and Orchestrating Nucleocytoplasmic Transport to Activate MAPK Signaling

Advanced Science, EarlyView.
Lactylation of UDP‐glucose dehydrogenase (UGDH) represses its enzymatic activity and causes glycosaminoglycans loss. In addition, UGDH lactylation facilitates its interaction with chromosome region maintenance 1 (CRM1) and promotes the nucleocytoplasmic transport.
Weiren Lan, Xueman Chen, Huai Yu, Jianzhao Ruan, Jingliang Kang, Xiaoyu Nie, Yumei Cao, Su'an Tang, Changhai Ding   +8 more
wiley   +1 more source