Results 61 to 70 of about 10,355 (182)

The effect of BSO-induced oxidative stress on histologic feature of testis: testosterone secretion and semen parameters in mice [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2014
Objective(s): Buthionine sulfoximine (BSO) inhibits synthesis of glutathione as the main intracellular antioxidant. The aim of the present study is to investigate the effect of BSO-induced oxidative stress on histological structure of testis ...
Fakhrosadat Sajjadian   +5 more
doaj  

N-acetylcysteine decreases malignant characteristics of glioblastoma cells by inhibiting Notch2 signaling

open access: yesJournal of Experimental & Clinical Cancer Research, 2019
Background Glioblastomas multiforme (GBM) is the most devastating primary intracranial malignancy lacking effective clinical treatments. Notch2 has been established to be a prognostic marker and probably involved in GBM malignant progression.
Jie Deng   +8 more
doaj   +1 more source

The responses of Ht22 cells to oxidative stress induced by buthionine sulfoximine (BSO)

open access: yesBMC Neuroscience, 2005
Background glutathione (GSH) is the most abundant thiol antioxidant in mammalian cells. It directly reacts with reactive oxygen species (ROS), functions as a cofactor of antioxidant enzymes, and maintains thiol redox potential in cells. GSH depletion has
Berry Marla J   +3 more
doaj   +1 more source

Effects of buthionine sulfoximine nifurtimox and benznidazole upon trypanothione and metallothionein proteins in Trypanosoma cruzi.

open access: yesBiological Research, 2004
Proteins rich in sulfhydryl groups, such as metallothionein, are present in several strains of the parasite Trypanosoma cruzi, the etiological agent of Chagas' disease.
JUAN DIEGO MAYA   +7 more
doaj  

Effect of β-Mercaptoethanol with and without BSO (DL-Buthionine Sulfoximine) on Resumption of Meiosis, in vitro Maturation and Embryo Development of Immature Mouse Oocytes [PDF]

open access: yesCell Journal, 2006
Introduction: The purpose of this study was to evaluated the effect of β-mercaptoethanol on resumption of meiosis, in vitro maturation of immature mouse oocytes and resulting embryo development with and without BSO (DL-Buthionine sulfoximine).
Hossein Eimani   +10 more
doaj  

Hypermethylation of GSTM5 and its effect on oxidation in myelodysplastic syndrome

open access: yesiLABMED
Background Hypermethylation of glutathione‐S‐transferase 5 (GSTM5) and its effect on oxidation in the pathogenesis of myelodysplastic syndrome (MDS) were investigated.
Chi Wang   +5 more
doaj   +1 more source

Modular trifluoromethylselenolation and fluoroalkylselenolation via Ag(I)-mediated selenium nitrogen exchange reaction of benzothiaselenazole-1-oxides

open access: yesGreen Synthesis and Catalysis
By virtue of benzothiaselenazole-1-oxides as versatile building blocks and masked sulfoximines, we present a novel and practical trifluoromethylselenolation/fluoroalkylselenolation strategy via Ag(I)-mediated selenium nitrogen exchange (SeNEx) reaction ...
Xinyue Lin   +6 more
doaj   +1 more source

Synthesis and Bioactivity of New Phosphorylated R,R’-substituted Sulfoximines

open access: yesMolecules, 2005
R,R’-disubstituted sulfoximines were phosphorylated with O,O–diethylchlorophosphate and phosphorothionate to obtain new organophosphorus compounds. Afterpurification they were characterized by GC-MS and 1H-NMR.
Susana Arnstein de Licastro   +1 more
doaj   +1 more source

Dual nitrogen species involved in foliar uptake of nitrogen dioxide in Arabidopsis thaliana

open access: yesPlant Signaling & Behavior, 2019
Foliar uptake of nitrogen dioxide (NO2) is governed by its reactive absorption mechanism, by which NO2 molecules diffuse through cell wall layers and simultaneously react with apoplastic ascorbate to form nitrous acid, which freely diffuses across ...
Misa Takahashi   +2 more
doaj   +1 more source

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