Results 41 to 50 of about 10,355 (182)

Thermal Nickel‐Catalyzed N‐Arylation of Sulfonimidamides With (Hetero)aryl Chlorides Enabled by PAd‐DalPhos Ligation

European Journal of Organic Chemistry, EarlyView.
The nickel‐catalyzed S═NH N‐arylation of sulfonimidamides is described, with useful demonstrated substrate scope involving inexpensive and widely available (hetero)aryl chloride reaction partners, including the active pharmaceutical ingredient chlorpromazine.
Samuel A. Fisher, Patrick L. DeRoy, Mark Stradiotto   +2 more
wiley   +1 more source

Photochemistry of N‐Phenyl Benzonaphthothiophene and Dinaphthothiophene Sulfoximines

European Journal of Organic Chemistry, EarlyView.
The sequential photorelease of nitrenes and atomic oxygen [O(3P)] from N‑phenyl benzonaphthothiophene and dinaphthothiophene sulfoximines is a rare photochemical phenomenon in which two reactive intermediates can be released from a single chromophore. The sequential photorelease of nitrenes and atomic oxygen [O(3P)] is a rare photochemical phenomenon ...
Henry J. Politte, Bashar Aziz, Riley J. N. Tharp, Ryan D. McCulla   +3 more
wiley   +1 more source

Knockdown of glutamate cysteine ligase catalytic subunit by siRNA causes the gold nanoparticles-induced cytotoxicity in lung cancer cells. [PDF]

PLoS ONE, 2015
Gold nanoparticles (GNPs) have shown promising medical applications in cancer treatment involved in the regulation of intracellular redox balance. Previously, we have reported that GNPs can trigger apoptosis and necrosis in human lung cancer cells (A549)
Min Liu, Yunxue Zhao, Xiumei Zhang
doaj   +1 more source

Adenosine Improves Mitochondrial Function and Biogenesis in Friedreich's Ataxia Fibroblasts Following L-Buthionine Sulfoximine-Induced Oxidative Stress

Biology, 2023
Adenosine is a nucleoside that is widely distributed in the central nervous system and acts as a central excitatory and inhibitory neurotransmitter in the brain.
Sze Yuen Lew, Nur Shahirah Mohd Hisam, Michael Weng Lok Phang, Syarifah Nur Syed Abdul Rahman, Rozaida Yuen Ying Poh, Siew Huah Lim, Mohd Amir Kamaruzzaman, Sze Chun Chau, Ka Chun Tsui, Lee Wei Lim, Kah Hui Wong   +10 more
doaj   +1 more source

Temporal variation in susceptibility of Euschistus heros (Hemiptera: Pentatomidae) to pyrethroids and neonicotinoids, and spatial patterns of control failure likelihood in southern Brazil

Pest Management Science, EarlyView.
Monitoring of Euschistus heros populations in Rio Grande do Sul, Brazil, from 2017 to 2026 revealed declining susceptibility to pyrethroids and neonicotinoids. Reduced susceptibility to λ‐cyhalothrin and acetamiprid persisted, whereas declines in susceptibility to bifenthrin, imidacloprid and certain pre‐formulated mixtures emerged more recently ...
Luiz F Warpechowski, Otavio Liberalesso, Daniela N Godoy, Arthur Dallanora, Jéssica LS Grzybowski, Venicius E Pretto, Ramon B Palharini, Oderlei Bernardi   +7 more
wiley   +1 more source

Pesticide use in integrated pest and pollinator management framework to protect pollinator health

Pest Management Science, Volume 81, Issue 4, Page 1691-1696, April 2025.
Integrated pest management (IPM) emphasizes non‐chemical methods, with pesticides as a last resort, while integrated pest and pollinator management (IPPM) integrates pollinator health into pest control strategies. Abstract Agricultural pesticides have historically been a critical tool in controlling pests and diseases, preventing widespread suffering ...
Ngoc T Phan, David J Biddinger, Edwin G Rajotte, Guy Smagghe, Gadi VP Reddy, Zong‐Xin Ren, Neelendra K Joshi   +6 more
wiley   +1 more source

Multiple Targets on the Gln3 Transcription Activator Are Cumulatively Required for Control of Its Cytoplasmic Sequestration

G3: Genes, Genomes, Genetics, 2016
A remarkable characteristic of nutritional homeostatic mechanisms is the breadth of metabolite concentrations to which they respond, and the resolution of those responses; adequate but rarely excessive.
Rajendra Rai, Jennifer J. Tate, Terrance G. Cooper   +2 more
doaj   +1 more source

The effect of oxidant and the non-oxidant alteration of cellular thiol concentration on the formation of protein mixed-disulfides in HEK 293 cells. [PDF]

PLoS ONE, 2008
Cellular molecules possess various mechanisms in responding to oxidant stress. In terms of protein responses, protein S-glutathionylation is a unique post-translational modification of protein reactive cysteines forming disulfides with glutathione ...
Jasen Lee Gilge, Michael Fisher, Yuh-Cherng Chai   +2 more
doaj   +1 more source

Selective excitatory effects of γ‐glutamyl‐glycine, a glutathione metabolite, on GluN1 NMDA and mGlu5 receptors impacting synaptic plasticity

British Journal of Pharmacology, EarlyView.
Background and Purpose Gamma‐glutamyl dipeptides are essentially produced after glutathione (GSH) degradation. While several γ‐glutamyl dipeptides have been detected in different organs and body fluids, their biological activity remains elusive. This is the case for γ‐Glutamyl‐Glycine (γ‐Glu‐Gly) which has been found in different brain areas.
Sandro Andreu, Victoria Gizzi, Ugo Pasco, Fatiha Sebih, Yattou Zitouni, Pablo Jimenez, Valérie Rolland, Alain Chavanieu, Sébastien Estaran, Matthieu Rousset, Thierry Cens, Guillaume Cazals, Pierre Charnet, Janique Guiramand, Catherine Cohen‐Solal, Claudine Ménard, Marie‐Céleste de Jésus Ferreira, Nathalie Chevallier, Sonia Cantel, Michel Vignes, Julien Roussel   +20 more
wiley   +1 more source

sulfoximines

, 2019
Citation: 'sulfoximines' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.S06126 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source