Results 61 to 70 of about 16,074 (250)

A Rare Case of Both Migraine Without Aura and Typical Aura Without Headache in the Absence of Typical Aura With Headache

open access: yesClinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT We report a rare case of a 61‐year‐old woman with two distinct migraine patterns—migraine without aura and typical aura without headache—coexisting independently for 3 years without overlapping typical aura with headache. Neurological evaluations were unremarkable. Sodium valproate significantly reduced the frequency of both types.
Osamu Akiyama   +2 more
wiley   +1 more source

Development and Validation of Liquid Chromatography-Tandem Mass Spectrometry Method for Simple Analysis of Sumatriptan and its Application in Bioequivalence Study

open access: yesPharmaceuticals, 2020
This work demonstrated a sensitive, selective, and simple liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for quantitation of sumatriptan in human plasma samples.
Wisut Wichitnithad   +5 more
doaj   +1 more source

Sumatriptan poisoning and its clinical presentation in humans: A case report

open access: yesClinical Case Reports, 2022
This case report displays some of the possible complications of sumatriptan poisoning, including nephritic syndrome.
Peyman Erfan Talab Evini   +7 more
doaj   +1 more source

Headache and pregnancy. a systematic review [PDF]

open access: yes, 2017
This systematic review summarizes the existing data on headache and pregnancy with a scope on clinical headache phenotypes, treatment of headaches in pregnancy and effects of headache medications on the child during pregnancy and breastfeeding, headache ...
A. Negro   +9 more
core   +1 more source

Feed‐Forward Deep Neural Networks Predict Substrate‐Specific Effects of Transporter Variants to Explain Drug Response Variability

open access: yesClinical and Translational Science, Volume 19, Issue 5, May 2026.
ABSTRACT Genetic variants in drug transporter genes shape the interindividual variability in drug response. However, their functional interpretation has remained limited due to the substrate dependence of variant effects. Existing predictors are substrate‐agnostic and cannot capture how a single amino acid change differentially affects transport across
Yoomi Park   +4 more
wiley   +1 more source

Protective effects of sumatriptan against optic nerve injury in rats via modulation of kynurenine pathway, oxidative stress and apoptosis [PDF]

open access: yesBioImpacts
Introduction: Traumatic optic neuropathy (TON) is an acute visual dysfunction subsequent to head and neck trauma. Despite immense efforts, there is no effective treatment to minimize the damage caused by TON.
Moein Ala   +7 more
doaj   +1 more source

Management of migraine [PDF]

open access: yes, 1999
Migraine is a complex neurovascular disease characterised by episodic attacks of severe headache accompanied by autonomic and neurological symptoms. Two types of migraine have been identified: (1) common migraine, or migraine without aura, occurring in ...
Farrugia, Isabelle
core  

Novel optimization of multi‐mechanistic approaches for the acute treatment of a migraine attack: A review

open access: yesHeadache: The Journal of Head and Face Pain, Volume 66, Issue 5, Page 1181-1192, May 2026.
Abstract Objective To highlight key factors required to optimize multi‐mechanistic approaches with oral combination treatments for the acute management of a migraine attack. Background Given the complex multi‐factorial nature of migraine, combining treatments with different mechanisms of action should improve outcomes compared to monotherapies, but ...
Stephen Silberstein, Alan M. Rapoport
wiley   +1 more source

Could Ginger Extract Be a Therapeutic Drug for Migraine?

open access: yesSciences of Phytochemistry, 2023
Migraine is a common neurological disorder that may be accompanied by vascular disturbances, Migraine is one of the most causes of disability worldwide.
Ahmed Abd El-Moniem Amer
doaj   +1 more source

Sumatriptan effects on morphine-induced antinociceptive tolerance and physical dependence: The role of nitric oxide [PDF]

open access: yes, 2018
Sumatriptan, a 5HT (5-hydroxytryptamine)1B/1D receptor agonist, showed neuroprotection in different studies. The aim of the present study was to investigate the effect of sumatriptan on morphine-induced antinociceptive tolerance and physical dependence.
Akbarian, Reihaneh.   +8 more
core  

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