Results 51 to 60 of about 16,074 (250)

Periorbital Nociception in a Progressive Multiple Sclerosis Mouse Model Is Dependent on TRPA1 Channel Activation

open access: yesPharmaceuticals, 2021
Headaches are frequently described in progressive multiple sclerosis (PMS) patients, but their mechanism remains unknown. Transient receptor potential ankyrin 1 (TRPA1) was involved in neuropathic nociception in a model of PMS induced by experimental ...
Diéssica Padilha Dalenogare   +15 more
doaj   +1 more source

DFN-02, Sumatriptan 10 mg Nasal Spray with Permeation Enhancer, for the Acute Treatment of Migraine: A Randomized, Double-Blind, Placebo-Controlled Study Assessing Functional Disability and Subject Satisfaction with Treatment. [PDF]

open access: yes, 2019
BackgroundThe commercial formulation of sumatriptan nasal spray is an effective option for migraine patients requiring or preferring a non-oral route of drug administration, but its utility is limited by poor absorption and tolerability issues. DFN-02, a
Brand-Schieber, Elimor   +3 more
core  

Lifestyle triggers of migraine: Sleep restriction and caffeine lower the threshold for migraine‐like responses in rats in a sex‐specific manner

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Sleep restriction (SR) and caffeine intake act as environmental modulators of migraine susceptibility. Their effects are sex‐dependent: Females show heightened sensitivity under both SR and caffeine conditions. Males require the combination of SR and caffeine to exhibit susceptibility.
Gabriel Camargo de Oliveira   +7 more
wiley   +1 more source

Comparative evaluation of the efficiency of a sumatriptan/dexketoprofen combination versus sumatriptan monotherapy in the treatment of a migraine attack

open access: yesНеврология, нейропсихиатрия, психосоматика, 2018
Migraine is a chronic brain disease with a high prevalence and a marked deterioration in quality of life. Triptans are the gold standard for migraine attack therapy, but they are not effective in all patients.
K. V. Skorobogatykh, Yu. E. Azimova
doaj   +1 more source

Subtype-Specific Off-Label Treatment of Rosacea

open access: yesCase Reports in Dermatology, 2021
We present 2 cases of rosacea that were successfully managed with off-label treatment. The first is a case of painful, exuding papulopustular lesions of the nose treated with rifaximin, and the other is a case of severe, debilitating and painful flushing
Nita Wienholtz   +3 more
doaj   +1 more source

Network meta-analysis of migraine disorder treatment by NSAIDs and triptans [PDF]

open access: yes, 2016
Node splitting of direct and indirect comparisons according to type of interventions for rescue medication and recurrence.
Haiyang Xu   +3 more
core   +2 more sources

What's Needed for a Migraine Cost‐Of‐Illness Study in Aotearoa New Zealand: Review of Data Sources and Gaps

open access: yesJournal of the Royal Society of New Zealand, Volume 56, Issue 3, June 2026.
Cost of illness (COI) studies are used to quantify the economic burden of disease on health systems, employers and society, and identify where costs may be saved by improvements in disease management. Many migraine COI studies have been published internationally but none have included data from Aotearoa New Zealand (NZ), despite the known high ...
Fiona Imlach   +5 more
wiley   +1 more source

Glassy Carbon Electrode Modified with CB/TiO2 Layer for Sensitive Determination of Sumatriptan by Means of Voltammetry and Flow Injection Analysis

open access: yesSensors, 2023
Sumatriptan is an organic chemical compound from the tryptamine group. It is used as a medicine for migraine attacks and in the treatment of cluster headaches.
Joanna Smajdor   +3 more
doaj   +1 more source

Efficacy and safety of DFN-11 (sumatriptan injection, 3 mg) in adults with episodic migraine: a multicenter, randomized, double-blind, placebo-controlled study. [PDF]

open access: yes, 2018
BackgroundIn a previous randomized, double-blind, proof-of-concept study in rapidly escalating migraine, a 3 mg dose of subcutaneous sumatriptan (DFN-11) was associated with fewer and shorter triptan sensations than a 6 mg dose.
Brand-Schieber, Elimor   +3 more
core   +1 more source

Calcitonin gene-related peptide receptor antagonist BIBN 4096 BS for the acute treatment of migraine [PDF]

open access: yes, 2004
Background: Calcitonin gene–related peptide (CGRP) may have a causative role in migraine. We therefore hypothesized that a CGRP-receptor antagonist might be effective in the treatment of migraine attacks.
Diener, H.-C.   +7 more
core   +1 more source

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