Results 31 to 40 of about 16,074 (250)
Serotonin reuptake inhibitors and cardiovascular disease [PDF]
, 2005 Selective serotonin re-uptake inhibiting drugs (SSRIs) are widely used for endogenous depression. In addition to depleting the nerve terminals of serotonin they also lower blood platelet serotonin levels.
Belcher, P.R. +2 more
core +1 more source
Therapeutic Advances in Neurological Disorders, 2015 An iontophoretic transdermal system (ITS) (skin patch) formulation of sumatriptan for the acute treatment of migraine attacks was approved by the US Food and Drug Administration in January 2013. This transdermal system bypasses the gastrointestinal tract,
Michail Vikelis +2 more
doaj +1 more source
Cluster headache management and beyond [PDF]
, 2015 The therapeutic management of cluster headache is based on a very stable triad of drugs. Acute treatment has, in subcutaneous sumatriptan, its gold standard if compared to pure oxygen or indomethacin.
Martelletti, Paolo
core +1 more source
The therapeutic armamentarium in migraine is quite elderly. [PDF]
, 2014 Global Burden of Disease 2010 study considers migraine as one of the most important noncommunicable diseases in the world, classifying it third in terms of global prevalence (14.70%): it sums up the 54.19% of all the years of life lived with disabilities
Martelletti, Paolo
core +1 more source
Motion sickness and migraine: optokinetic stimulation increases scalp tenderness, pain sensitivity in the fingers and photophobia [PDF]
, 2002 The aim of this study was to determine whether scalp tenderness and photophobia, two well-recognized symptoms of migraine, develop during the motion sickness induced by optokinetic stimulation.
Drummond, P.D.
core +2 more sources
Use of factorial design in formulation and evaluation of intrarectal in situ gel of sumatriptan
Journal of Advanced Pharmaceutical Technology & Research, 2023 The study's goal was to create an in situ intrarectal mucoadhesive gel of sumatriptan (SMT) combining mucoadhesive polymer (xyloglucan) and thermosensitive polymers (poloxamer 407 and poloxamer 188) to prolong rectal residence time for treatment of ...
Hanan J Kassab +2 more
doaj +1 more source
Effect of CGRP and sumatriptan on the BOLD response in visual cortex [PDF]
, 2012 To test the hypothesis that calcitonin gene-related peptide (CGRP) modulates brain activity, we investigated the effect of intravenous CGRP on brain activity in response to a visual stimulus.
Adam E. Hansen +4 more
core +2 more sources
A Systematic Review and Economic Evaluation of Sumatriptan Nasal Spray Versus its Oral Tablet
Journal of Pharmacoeconomics and Pharmaceutical Management, 2021 Background: Sumatriptan is one of the leading medicines in migraine treatment. This study aimed to evaluate the cost-effectiveness (in the context of Iran) of sumatriptan nasal spray versus its oral tablet for treating migraine headaches.
Golnoosh Alipour Haris +5 more
doaj
Cilostazol induced migraine does not respond to sumatriptan in a double blind trial
The Journal of Headache and Pain, 2018 Background Cilostazol is an inhibitor of phosphodiesterase 3 and thus causes accumulation of cAMP. It induces migraine-like attacks in migraine patients. Whether the cilostazol model responds to sumatriptan in migraine patients and therefore is valid for
Katrine Falkenberg +4 more
doaj +1 more source
Therapeutic Advances in Neurological Disorders, 2009 A novel composite endpoint, sustained pain-free/no adverse events, was recently proposed as a more rigorous means of capturing in a single measure the attributes of migraine pharmacotherapy that patients consider most important: rapid and sustained pain ...
Stephen Landy +3 more
doaj +1 more source