Results 241 to 250 of about 291,935 (374)

Unraveling the critical role of SUMOylation in the governing of tumor immunity. [PDF]

Front Immunol
Liu X, Ding W, Jiang L, Chen Q, Luo X.
europepmc   +1 more source

Winning Isn't Everything: Corruption in Sumo Wrestling

, 2000
Mark Duggan, Steven D. Levitt
openalex   +1 more source

SenExo‐cCCT2 Reprograms Senescence Response and Anti‐Tumor Immunity Following FOLFIRINOX Chemotherapy in Pancreatic Ductal Adenocarcinoma

Advanced Science, Volume 12, Issue 38, October 13, 2025.
This study demonstrates that SenExo‐cCCT2 enables targeted delivery of cCCT2 to pancreatic cancer cells, where it disrupts IPO13‐mediated nuclear translocation of UBC9, impairing SUMOylation‐dependent DNA damage repair and inducing senescence. Senescent tumor cells secrete CXCL10 to recruit CD8⁺ T‐cells while upregulating PD‐L1.
Shuncang Zhu, Yinhao Chen, Hongyi Lin, Jinpeng Lu, Yu Pan, Ge Li, Yongding Wu, Haoxiang Zhang, Xiaoxiao Huang, Yiting Chen, Huangjing Chen, Long Jin, Min Huang, Chengyu Liao, Long Huang, Yifeng Tian, Zuwei Wang, Qiaowei Li, Shi Chen   +18 more
wiley   +1 more source

N-Terminal Metal-Binding Domain of Arabidopsis IBR5 Is Important for Its in Planta Functions. [PDF]

Int J Mol Sci
Yeon J, Lim J, Song SK, Yi H.
europepmc   +1 more source

PIAS3 induces SUMO‐1 modification and transcriptional repression of IRF‐1 [PDF]

, 2002
Koji Nakagawa, Hideyoshi Yokosawa
openalex   +1 more source

Modulation of Aging Diseases via RAGE Targets: A Dietary Intervention Review

Advanced Science, Volume 12, Issue 38, October 13, 2025.
This paper analyzes RAGE ligand‐binding mechanisms and signaling, proposing intervention strategies targeting these interactions. It emphasizes dietary polyphenols, polysaccharides, and terpenoids delivered via functional foods for anti‐aging. These compounds offer long‐term, safe intervention through dietary supplementation, providing dual nutritional
Qian Wu, Jia Yan, Yuyan Zhang, Xiaozhi Ming, Siqi Chen, Zhichao Zou, Nianjie Feng, Jianbo Xiao   +7 more
wiley   +1 more source

Identification of SUMO Proteins and Their Expression Profile During Induction of Somatic Embryogenesis in <i>Medicago truncatula</i> Gaertn. [PDF]

Int J Mol Sci
Kujawska A, Król P.
europepmc   +1 more source

Detection of Genome‐Wide IGF‐1R Recruitment to Enhancer and Promoter Regions of Chromatin in Clinical Prostate Cancers

Cancer Medicine, Volume 14, Issue 19, October 2025.
ABSTRACT Introduction Nuclear insulin‐like growth factor‐1 receptor (IGF‐1R) undergoes IGF‐induced recruitment to cancer cell chromatin in vitro and associates with advanced prostate cancer (PCa) stage in clinical tissue, prompting this investigation of IGF‐1R chromatin recruitment in vivo. Methods Human tissues surplus to diagnostic need were obtained
Jack V. Mills, Avigail Taylor, Reema Singh, Jinseon Kim, Simon Engledow, Richard Colling, Clare Verrill, Ian G. Mills, Valentine M. Macaulay   +8 more
wiley   +1 more source

SUMO-Mediated Regulation of Nuclear Functions and Signaling Processes.

Molecules and Cells, 2018
Xiaolan Zhao
semanticscholar   +1 more source

Histone deacetylase genes in lotus seed maturation: Identification and expression pattern analysis

eFood, Volume 6, Issue 5, October 2025.
Fourteen HDACs were identified and characterized from lotus seed. NnHDA3 may be involved in the maturation and senescence of lotus seeds. NnHDA2 and NnSRT1 are involved in the metabolism of chlorophyll and starch during lotus seed ripening. Abstract Histone deacetylase (HDAC) plays an essential role in plant growth, development, and maturation ...
Shiqi Zheng, Yanchao Han, Weijie Wu, Xiangjun Fang, Ben Niu, Ruiling Liu, Hangjun Chen, Haiyan Gao   +7 more
wiley   +1 more source