Results 241 to 250 of about 300,823 (367)

Biochemical and Comparative Proteomic Analyses Delineate the Anti‐Ovarian Carcinogenic Roles of Modified Calycosin

Food Science &Nutrition, Volume 14, Issue 1, January 2026.
The modified calycosin derivative H10 was more effective in inhibiting cell proliferation through G0/G1 cell cycle arrest, together with inhibiting the migration and colony formation abilities of ovarian cancer cell lines SKOV3 and A2780. Comparative proteomic analysis coupled with Ingenuity Pathway Analysis further delineated calycosin derivative H10 ...
Fuhong Yang, Xin Li, Hanchi Gao, Pei Yao, Xian Qin, Xiao Lin, Keng Po Lai, Jing Tian, Jian Chen   +8 more
wiley   +1 more source

Targeting SUMOylation with Anacardic Acid Derivatives: Novel Insights into EGF Pathway Dysregulation in Cancer Using an In Silico Approach. [PDF]

ACS Omega
Padmakumar S, Gopichand B, Melge AR, Madhavan A, Babu P, Nair BG, Perry JJP, Kumar GB.   +7 more
europepmc   +1 more source

Molecular mechanistic insights into the OX40–OX40L complex from biophysical and computational analyses

Protein Science, Volume 35, Issue 1, January 2026.
Abstract OX40 and OX40L belong to the tumor necrosis factor receptor superfamily (TNFRSF) and tumor necrosis factor superfamily (TNFSF), respectively. Protein–protein interactions between OX40 and OX40L facilitate T cell responses, triggering various immunological and pathophysiological events.
Hiro Nishimuta, Akinobu Senoo, Keisuke Kasahara, Taito Kubo, Saeko Yanaka, Satoru Nagatoishi, Takanori So, Tadashi Ueda, Kouhei Tsumoto, Jose M. M. Caaveiro   +9 more
wiley   +1 more source

Chicken PIAS2 enhances H6N2 avian influenza virus replication by promoting SUMOylation of viral NP. [PDF]

Vet Res
Zhang J, Xue Q, Wang X, Yang H, Huang M, Zhang M, Zhao L, Wang W, Chen Z, Jiao P.   +9 more
europepmc   +1 more source

RePol: A high‐throughput screen for optimizing membrane protein solubilization and purification using polymers

Protein Science, Volume 35, Issue 1, January 2026.
Abstract Extraction and purification of membrane proteins has for a long time represented a significant challenge. Polymer‐based extraction methods, like those using styrene maleic acid co‐polymers have provided a fertile approach to generate samples that include the local lipid environment surrounding the protein.
Adam Evans, Bethan Kelly, Pooja Sridhar, Alice J. Rothnie, Naomi L. Pollock, Philip M. Ireland, David I. Roper, Tim R. Dafforn   +7 more
wiley   +1 more source

Exploring the ubiquitination regulatory network: opening new perspectives for rheumatoid arthritis therapy. [PDF]

Ann Med
Wang F, Liu J, Wen J, Sun Y, He M.
europepmc   +1 more source

Identification and Molecular Properties of SUMO-Binding Proteins in Arabidopsis [PDF]

, 2011
Hyeong Cheol Park, Wonkyun Choi, Hee Jin Park, Mi Sun Cheong, Yoon Duck Koo, Gilok Shin, Woo Sik Chung, Woe‐Yeon Kim, Min Gab Kim, Ray A. Bressan, Hans J. Bohnert, Sang Yeol Lee, Dae‐Jin Yun   +12 more
openalex   +1 more source

Regarding the importance of population diversity validation in Alzheimer's disease models

Alzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Paul D. Coleman, Elaine Delvaux, Ashley Boehringer, Carol J. Huseby   +3 more
wiley   +1 more source

ECLYPSE: A Python Framework for Simulation and Emulation of the Cloud‐Edge Continuum

Journal of Software: Evolution and Process, Volume 38, Issue 1, January 2026.
ABSTRACT The Cloud‐Edge continuum enhances application performance by bringing computation closer to data sources. However, it presents considerable challenges in managing resources and determining application service placement, as these tasks require analyzing diverse, dynamic environments characterized by fluctuating network conditions.
Jacopo Massa, Valerio De Caro, Stefano Forti, Patrizio Dazzi, Davide Bacciu, Antonio Brogi   +5 more
wiley   +1 more source

Simulated Microgravity-Induced Changes in SUMOylation and Protein Expression in <i>Saccharomyces cerevisiae</i>. [PDF]

Int J Mol Sci
Sabo JA, Hartson SD.
europepmc   +1 more source