Results 221 to 230 of about 35,698 (247)

Sumoylation in neurodegenerative diseases

Cellular and Molecular Life Sciences, 2012
The yeast SUMO (small ubiquitin-like modifier) orthologue SMT3 was initially discovered in a genetic suppressors screen for the centromeric protein Mif2 (Meluh and Koshland in Mol Bio Cell 6:793-807, 1). Later, it turned out that the homologous mammalian proteins SUMO1 to SUMO4 are reversible protein modifiers that can form isopeptide bonds with lysine
Petranka, Krumova, Jochen H, Weishaupt
openaire   +2 more sources

Sumoylation in Craniofacial Disorders

2009
Craniofacial development requires a complex series of coordinated and finely tuned events to take place, during a relatively short time frame. These events are set in motion by switching on and off transcriptional cascades that involve the use of numerous signalling pathways and a multitude of factors that act at the site of gene transcription.
Erwin, Pauws, Philip, Stanier
openaire   +2 more sources

SUMOylation in Neurodegenerative Diseases

Gerontology, 2019
Posttranslational modifications are ubiquitous regulators of cellular processes. The regulatory role of SUMOylation, the attachment of a small ubiquitin-related modifier to a target protein, has been implicated in fundamental processes like cell division, DNA damage repair, mitochondrial homeostasis, and stress responses.
Princz, Andrea, Tavernarakis, Nektarios
openaire   +2 more sources

Analysis of Protein Sumoylation

Current Protocols in Protein Science, 2016
AbstractSumoylation, wherein small ubiquitin‐like modifier (SUMO) proteins are covalently attached to specific lysine residues of target proteins, plays an important role in regulating many diverse cellular processes via its control of the functional properties of the modified proteins.
openaire   +2 more sources

SUMOylation in Viral Replication and Antiviral Defense

Advanced Science, 2022
Long Zhang, Zhi Zong, Fangwei Wang
exaly  

SUMOylation of SUMOylation proteins

Reactome - a curated knowledgebase of biological pathways, 2018
openaire   +1 more source

Fine‐tuning of SUMOylation modulates drought tolerance of apple

Plant Biotechnology Journal, 2022
Xuewei Li, Pengxiang Chen, Shuang Zhao   +2 more
exaly  

Histone sumoylation and chromatin dynamics

Nucleic Acids Research, 2021
Hong-Yeoul Ryu, Mark Hochstrasser, Ryu Hong-Yeoul   +2 more
exaly  

SUMOylation

2008
Ruth Geiss‐Friedlander, Frauke Melchior   +1 more
openaire   +2 more sources

Current Status of SUMOylation Inhibitors

Current Medicinal Chemistry, 2021
Christopher M Brackett, Brian S J Blagg
exaly