Results 51 to 60 of about 19,250 (186)

Nuclear SUN1 Stabilizes Endothelial Cell Junctions via Microtubules to Regulate Blood Vessel Formation [PDF]

, 2021
ABSTRACT Endothelial cells line all blood vessels, where they coordinate blood vessel formation and the blood-tissue barrier via regulation of cell-cell junctions. The nucleus also regulates endothelial cell behaviors, but it is unclear how the nucleus contributes to endothelial cell activities at the cell periphery ...
Danielle B Buglak, Molly R Kulikauskas, Ziqing Liu, Ariel L Gold, Allison P Marvin, Andrew Burciu, Natalie T Tanke, Shea N Ricketts, Karina Kinghorn, Morgan Oatley, Bryan N Johnson, Pauline Bougaran, Celia E Shiau, Stephen L Rogers, Victoria L Bautch   +14 more
openaire   +1 more source

SUN1 Is Required for Telomere Attachment to Nuclear Envelope and Gametogenesis in Mice [PDF]

Developmental Cell, 2007
Prior to the pairing and recombination between homologous chromosomes during meiosis, telomeres attach to the nuclear envelope and form a transient cluster. However, the protein factors mediating meiotic telomere attachment to the nuclear envelope and the requirement of this attachment for homolog pairing and synapsis have not been determined in ...
Ding, Xu, Xu, Rener, Yu, Juehua, Xu, Tian, Zhuang, Yuan, Han, Min   +5 more
openaire   +2 more sources

A homozygous KASH5 frameshift mutation causes diminished ovarian reserve, recurrent miscarriage, and non-obstructive azoospermia in humans

Frontiers in Endocrinology, 2023
The meiosis-specific LINC complex, composed of the KASH5 and SUN1 proteins, tethers the moving chromosomes to the nuclear envelope to facilitate homolog pairing and is essential for gametogenesis.
Xiaoning Hou, Xiaoning Hou, Xiaoning Hou, Xiaoning Hou, Aurang Zeb, Aurang Zeb, Aurang Zeb, Aurang Zeb, Sobia Dil, Sobia Dil, Sobia Dil, Sobia Dil, Jianteng Zhou, Jianteng Zhou, Jianteng Zhou, Jianteng Zhou, Huan Zhang, Huan Zhang, Huan Zhang, Huan Zhang, Baolu Shi, Baolu Shi, Baolu Shi, Baolu Shi, Zubair Muhammad, Zubair Muhammad, Zubair Muhammad, Zubair Muhammad, Ihsan Khan, Ihsan Khan, Ihsan Khan, Ihsan Khan, Qamar Zaman, Qamar Zaman, Qamar Zaman, Qamar Zaman, Wasim Akbar Shah, Wasim Akbar Shah, Wasim Akbar Shah, Wasim Akbar Shah, Xiaohua Jiang, Xiaohua Jiang, Xiaohua Jiang, Xiaohua Jiang, Limin Wu, Limin Wu, Limin Wu, Limin Wu, Hui Ma, Hui Ma, Hui Ma, Hui Ma, Qinghua Shi, Qinghua Shi, Qinghua Shi, Qinghua Shi   +55 more
doaj   +1 more source

SUN/KASH interactions facilitate force transmission across the nuclear envelope. [PDF]

, 2019
LINC complexes (Linker of Nucleoskeleton and Cytoskeleton), consisting of inner nuclear membrane SUN (Sad1, UNC-84) proteins and outer nuclear membrane KASH (Klarsicht, ANC-1, and Syne Homology) proteins, are essential for nuclear positioning, cell ...
Hao, Hongyan, Starr, Daniel A
core  

Measurements of J/psi decays into phi pi^0, phi eta, and phi eta^prime

, 2004
Based on 5.8x10^7 J/psi events detected in BESII, the branching fractions of J/psi--> phi eta and phi eta^prime are measured for different eta and eta^prime decay modes. The results are significantly higher than previous measurements. An upper limit on B(
B. A. Zhuang, B. Q. Zhou, B. S. Zou, B. X. Zhang, B. Xin, B. Y. Zhang, C. C. Zhang, C. D. Fu, C. D. Qian, C. H. Jiang, C. L. Luo, C. L. Wei, C. S. Gao, C. S. Yu, C. X. Liu, C. Z. Yuan, D. H. Wei, D. H. Zhang, D. L. Shen, D. P. Jin, D. X. Zhao, D. Y. Wang, F. A. Harris, F. C. Ma, F. Li, F. Liu, F. Lu, F. Shi, F. Yang, Fang Liu, G. F. Xu, G. L. Tong, G. Li, G. M. Zhou, G. R. Lu, G. Rong, G. S. Huang, G. S. Varner, G. W. Yu, H. B. Liao, H. F. Chen, H. H. Li, H. H. Liu, H. J. Lu, H. L. Dai, H. L. Ma, H. M. Hu, H. M. Liu, H. P. Peng, H. Q. Zheng, H. Qin, H. S. Chen, H. S. Sun, H. X. Chen, H. X. Yang, H. Xu, H. Y. Fu, H. Y. Sheng, H. Y. Zhang, J. B. Liu, J. B. Zhao, J. C. Chen, J. C. Li, J. F. Chang, J. F. Qiu, J. F. Sun, J. Fang, J. G. Bian, J. G. Lu, J. Li, J. Liu, J. M. Ma, J. M. Yuan, J. Nie, J. P. Liu, J. P. Zheng, J. Ranft, J. W. Zhang, J. W. Zhao, J. Y. Zhang, J. Yang, J. Z. Bai, J. Z. Wang, J. Zhang, Jin Chen, Jun Chen, K. Hanssgen, K. J. Zhu, K. L. He, K. Wang, L. H. Yi, L. L. Ma, L. S. Wang, L. S. Zheng, L. Shang, L. Wang, L. X. Luo, L. Y. Dong, L. Y. Shan, L. Zhou, M. Ablikim, M. G. Zhao, M. H. Ye, M. He, M. L. Chen, M. L. Yan, M. Wang, M. Y. Gong, M. Ye, N. D. Qi, N. F. Zhou, N. Tao, N. Wu, P. L. Wang, P. P. Zhao, P. Wang, Q. F. Dong, Q. J. Li, Q. J. Zhang, Q. M. Ma, Q. M. Zhu, R. G. Liu, R. Y. Li, S. D. Gu, S. Jin, S. L. Olsen, S. L. Zang, S. M. Li, S. P. Chi, S. Q. Zhang, S. S. Fang, S. S. Sun, S. T. Xue, S. X. Du, S. Z. Wang, S. S. Fang, T. Hu, W. D. Li, W. F. Wang, W. G. Li, W. R. Zhao, W. X. Gong, X. A. Zhuang, X. B. Ji, X. B. Ma, X. C. Zhong, X. Cai, X. H. Mo, X. He, X. J. Zhao, X. L. Li, X. L. Luo, X. M. Xia, X. M. Zhang, X. P. Huang, X. Q. Li, X. S. Jiang, X. Shi, X. T. Huang, X. Tang, X. X. Xie, X. Y. Ma, X. Y. Shen, X. Y. Zhang, X. Z. Cui, Y. B. Chen, Y. B. Zhao, Y. Ban, Y. C. Zhu, Y. F. Lai, Y. F. Liang, Y. F. Wang, Y. Jin, Y. K. Heng, Y. L. Li, Y. M. Wu, Y. N. Gao, Y. N. Guo, Y. P. Chu, Y. Q. Guo, Y. R. Tian, Y. S. Dai, Y. S. Zhu, Y. X. Yang, Y. X. Ye, Y. Y. Zhang, Y. Yuan, Y. Z. Sun, Y. Zeng, Yi Jin, Yingchun Zhu, Yiyun Zhang, Yu Zeng, Z. A. Liu, Z. A. Zhu, Z. D. Nie, Z. G. Zhao, Z. J. Guo, Z. J. Sun, Z. P. Mao, Z. P. Zhang, Z. P. Zheng, Z. Q. Zhang, Z. Wang, Z. X. Liu, Z. Y. Deng, Z. Y. Ren, Z. Y. Wang, Z. Y. Yi, Z. Z. Du, Zhe Wang, Zheng Wang   +211 more
core   +1 more source

Nuclear Entanglement: New Insights Into the Role of Cytoskeleton and Nucleoskeleton in Plant Nuclear Function

Cytoskeleton, EarlyView.
ABSTRACT Of the three types of cytoskeleton known in animals—actin, microtubules, and intermediate filaments—only actin and microtubules exist in plants. Both play important roles in cellular shaping, organelle movement, organization of the endomembrane system, and cell signaling.
Norman R. Groves, Katelyn Amstutz, Lily A. Schumacher, Iris Meier   +3 more
wiley   +1 more source

Brightness Characterization of SUN1 and SUN2 by Z-Scan Fluorescence Fluctuation Spectroscopy [PDF]

Biophysical Journal, 2016
Fluorescence fluctuation spectroscopy (FFS) has been used to quantify the stoichiometry of soluble proteins in the cytoplasm of cells by brightness analysis. The development of z-scan FFS broadened the capability of brightness analysis to include proteins distributed across stratified layers, such as the cytoplasm and the plasma membrane.
Saunders, Cosmo A., Hennen, Jared, Smith, Elizabeth M., Mueller, Joachim D., Luxton, G.W. Gant   +4 more
openaire   +1 more source

Heat Stress Triggers Nuclear Invagination and Spatial Compartmentalization of Protein Metabolism

Cell Proliferation, EarlyView.
Cells adapt heat stress to shape a nuclear invagination region function as “protein metabolism hotspots”, where both protein production and degradation are enhanced. ABSTRACT Heat stress is a common challenge for cells, causing multiple types of cellular damage while triggering complex stress responses, including the highly conserved mechanism known as
Zhi‐Hao Zhang, Yuan‐Tao Qiu, Jing‐Yue Cao, Yi‐Feng Huang, Ye‐Lin Lan, Yu‐Li Zhao, Fu Wu, Chen‐Long Wang, Guo‐Run Tang, Jing‐Yun Ji, Zhang Zhang, Guan‐Zheng Luo   +11 more
wiley   +1 more source

Expansion of the Phenotypic and Genotypic Spectrum for PRKAR1B ‐Related Marbach–Schaaf Neurodevelopmental Syndrome: A Case Series

Clinical Genetics, Volume 109, Issue 4, Page 679-696, April 2026.
Comprehensive clinical description of 12 subjects with pathogenic PRKAR1B variants, including two heterozygous deletions supporting haploinsufficiency as a possible mechanism of disease, providing valuable insight into the pathophysiology of MASNS and setting a framework upon which to design future mechanistic studies of PKA signaling in brain ...
Sebastian Burkart, Tarik Guzeloglu, Ana R. Soares, Irene Valenzuela, Eduardo F. Tizzano, David Gómez‐Andres, Laurent Pasquier, Marine Legendre, Camille Berges, Julien Thevenon, Marjolaine Gauthier, Caleb Heid, Elly Ranum, Joseph Shen, Michelle Frees, Michael W. Schmidtke, Caro Pilar, Christian P. Schaaf   +17 more
wiley   +1 more source

A molecular mechanism for LINC complex branching by structurally diverse SUN-KASH 6:6 assemblies

eLife, 2021
The Linker of Nucleoskeleton and Cytoskeleton (LINC) complex mechanically couples cytoskeletal and nuclear components across the nuclear envelope to fulfil a myriad of cellular functions, including nuclear shape and positioning, hearing, and meiotic ...
Manickam Gurusaran, Owen Richard Davies
doaj   +1 more source