Results 51 to 60 of about 1,305 (130)

CPOP1 is a key enzyme required for nodule microenvironment control and successful symbiotic nitrogen fixation in Lotus japonicus

open access: yesJournal of Integrative Plant Biology, Volume 67, Issue 12, Page 3167-3181, December 2025.
The enzyme coproporphyrinogen III oxidase plastid related 1 (CPOP1) creates a low‐oxygen nodule environment for nitrogen fixation within nodules of Lotus japonicus. CPOP1 makes heme, which helps control oxygen, and acts in infected cells; its knockout raises oxygen levels, suppresses nitrogen‐fixing enzyme activity, and halts nitrogen fixation ...
Yu‐Fang Tian   +5 more
wiley   +1 more source

Status Dystonicus in Children: Is it more Common than we Realize?

open access: yesMovement Disorders Clinical Practice, Volume 12, Issue 10, Page 1629-1634, October 2025.
Abstract Background Status dystonicus (SD) is the most severe form of dystonia, affecting predominantly children. SD is thought to be rare, but the incidence is unknown. Objective We aimed to: (1) assess the number of admissions involving SD (2) describe complications/intensive care unit (ICU) transfers, and (3) evaluate whether these changed with ...
Nadia Al Azri   +6 more
wiley   +1 more source

Microbial diversity and function in the rhizosphere microbiome: Driving forces and monitoring approaches

open access: yesAgrosystems, Geosciences &Environment, Volume 8, Issue 3, September 2025.
Abstract As an ecological unit, the rhizosphere microbiome preserves an enormous and largely unexplored diversity of microbes that play essential roles in plant health and soil functions. Omics technologies encompassing high‐throughput approaches such as metagenomics, metatranscriptomics, and metaproteomics provide helpful tools to unravel the ...
Chinenyenwa Fortune Chukwuneme   +1 more
wiley   +1 more source

DNA-based diagnosis of isolated sulfite oxidase deficiency by denaturing high-performance liquid chromatography

open access: yes, 2002
Isolated sulfite oxidase deficiency is a rare autosomal recessive disease, characterized by severe neurological abnormalities, seizures, mental retardation, and dislocation of the ocular lenses, that often leads to death in infancy.
Tong, SF   +8 more
core   +1 more source

The Regulation of Trace Metal Elements in Cancer Ferroptosis

open access: yesAdvanced Biology, Volume 9, Issue 8, August 2025.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang   +5 more
wiley   +1 more source

The sulfite oxidase Shopper controls neuronal activity by regulating glutamate homeostasis in Drosophila ensheathing glia

open access: yes, 2018
Specialized glial subtypes provide support to developing and functioning neural networks. Astrocytes modulate information processing by neurotransmitter recycling and release of neuromodulatory substances, whereas ensheathing glial cells have not been ...
Thomas, Silke   +14 more
core   +1 more source

Proteomic Profiling Informs Mechanisms of Esophageal Adenocarcinoma Inhibition by Cranberry Proanthocyanidins

open access: yesMolecular Nutrition &Food Research, Volume 69, Issue 15, August 2025.
In this study we utilized proteomic profiling to investigate mechanisms linked to the cancer‐inhibitory effect of cranberry proanthocyanidins (CPACs) on reflux‐induced esophageal adenocarcinoma in a rat model. The results indicate that CPAC inhibits cancer through targeting multiple hallmarks of cancer known to be dysregulated in progression to ...
Yun Zhang   +7 more
wiley   +1 more source

D-Bifunctional Protein Deficiency Diagnosis-A Challenge in Low Resource Settings: Case Report and Review of the Literature. [PDF]

open access: yesInt J Mol Sci
D-bifunctional protein deficiency (D-BPD) is a rare, autosomal recessive peroxisomal disorder that affects the breakdown of long-chain fatty acids. Patients with D-BPD typically present during the neonatal period with hypotonia, seizures, and facial ...
Ognean ML   +9 more
europepmc   +2 more sources

Hypoxia Disrupts Sex‐Specific Physiology and Gene Expression Leading to Decreased Fitness in the Estuarine Sea Anemone Nematostella vectensis

open access: yesMolecular Ecology, Volume 34, Issue 9, May 2025.
ABSTRACT Coastal seawater hypoxia is increasing in temperate estuaries under global climate change, yet it is unknown how low oxygen conditions affect most estuarine species. We found that hypoxia has increased since the 1990s in an estuary hosting the sea anemone Nematostella vectensis (Jacques Cousteau National Estuarine Research Reserve, New Jersey,
Benjamin H. Glass   +5 more
wiley   +1 more source

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