Results 161 to 170 of about 12,609 (207)

The bacterial superantigen and superantigen‐like proteins

open access: yesImmunological Reviews, 2008
Summary: The bacterial superantigens are protein toxins that bind to major histocompatibility complex class II and T‐cell receptor to stimulate large numbers of T cells. The majority are produced by the Gram‐positive organisms Staphylococcus aureus and Streptococcus pyogenes and are the causative agents in toxic shock syndrome, an acute disease caused
John D Fraser, Thomas Proft
exaly   +4 more sources

Superantigens

Current Biology, 1992
Over the past three years superantigens have come to the forefront of immunological research. Studies in a number of laboratories have indicated that superantigens play a central role in shaping the T-cell repertoire in the development of tolerance, autoimmunity and immunodeficiency.
T, Chatila, R S, Geha
openaire   +6 more sources

Functional Evaluation of HIV/SIV Nef as Superantigen

open access: yesVirology, 2001
It is speculated that a virus-encoded superantigen is involved in the pathogenesis of human and simian immunodeficiency virus infections and that the accessory protein Nef might be that superantigen.
Gerd Sutter   +2 more
exaly   +2 more sources

Superantigens

Otolaryngologic Clinics of North America, 2010
Superantigens (SAgs) are derived from diverse sources, including bacteria, viruses, and human hepatic tissue. SAgs initially cause lymphocyte activation but then result in clonal deletion and anergy, leading to immune tolerance. They can also act as superallergens by stimulating a broad spectrum of mast cells and basophils in patients with allergic ...
Stow, Nicholas W.   +3 more
openaire   +3 more sources

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