Results 61 to 70 of about 13,743 (223)

Staphylococcus aureus Toxins and Their Molecular Activity in Infectious Diseases

open access: yesToxins, 2018
Staphylococcus aureus is a microorganism resident in the skin and nasal membranes with a dreadful pathogenic potential to cause a variety of community and hospital-acquired infections.
Diana Oliveira   +2 more
doaj   +1 more source

Multiple Roles of Staphylococcus aureus Enterotoxins: Pathogenicity, Superantigenic Activity, and Correlation to Antibiotic Resistance

open access: yesToxins, 2010
Heat-stable enterotoxins are the most notable virulence factors associated with Staphylococcus aureus, a common pathogen associated with serious community and hospital acquired diseases.
Antonio Gálvez   +3 more
doaj   +1 more source

Direct manipulation of T lymphocytes by proteins of gastrointestinal bacterial pathogens [PDF]

open access: yes, 2018
Gastrointestinal bacterial infection represents a significant threat to human health, as well as a burden on food animal production and welfare. Although there is advanced knowledge about the molecular mechanisms underlying pathogenesis, including the ...
Abe J, Arencibia I, Barber MA, Stuart PM
core   +1 more source

Mycobacterium avium Subsp. paratuberculosis and Human Endogenous Retrovirus in Italian Patients With Inflammatory Bowel Disease (IBD) and Irritable Bowel Syndrome (IBS)

open access: yesImmunology, EarlyView.
Inflammatory bowel disease (IBD), comprising ulcerative colitis (UC) and Crohn's disease (CD), is a recognised gastrointestinal disorder. Mycobacterium avium subspecies paratuberculosis (MAP) is implicated in IBD pathogenesis. Persistent exposure and active infections by MAP may contribute to the unsilencing of human endogenous retroviruses (HERV ...
Stefano Ruberto   +14 more
wiley   +1 more source

Superantigen architecture: Functional decoration on a conserved scaffold [PDF]

open access: yes, 2007
A defining and consistent feature of the bacterial superantigens from Staphylococcus aureus and Streptococcus pyogenes is their strongly conserved three-dimensional structure.
Arcus, Vickery L., Baker, Edward N.
core   +1 more source

Blood Immunopathology of Tuberculosis Patients Disrupts Monocyte‐Dependent T‐Cell Activation and Cytokine Expression

open access: yesImmunology, EarlyView.
TB serum selectively disrupts monocyte‐dependent PHA T cell activation and cytokines associated with proliferation while preserving SEB T cell and Pam3/PHA monocyte cytokine responses. ABSTRACT Pulmonary tuberculosis in humans is characterised by features of immunopathology, which influence both antimycobacterial therapy and the long‐term prognosis. In
Joseph F. Arthur   +20 more
wiley   +1 more source

Phenotypes and Virulence among Staphylococcus aureus USA100, USA200, USA300, USA400, and USA600 Clonal Lineages

open access: yesmSphere, 2016
Staphylococcus aureus diseases affect ~500,000 individuals per year in the United States. Worldwide, the USA100, USA200, USA400, and USA600 lineages cause many of the life-threatening S.
Jessica M. King   +4 more
doaj   +1 more source

Genomic analysis of ERVWE2 locus in patients with multiple sclerosis: absence of genetic \ud association but potential role of human endogenous retrovirus type W elements in \ud molecular mimicry with myelin antigen [PDF]

open access: yes, 2013
Human endogenous retroviruses (HERVs) arise from ancient infections of the host germline cells by exogenous retroviruses, constituting 8% of the human genome.
Augusto Cesar Penalva de Oliveira   +13 more
core   +2 more sources

Identifying Cytokine Motif‐Containing, Immunomodulatory Bacterial Proteins in Human Gut Microbiome

open access: yesAdvanced Science, Volume 13, Issue 29, 22 May 2026.
By building and constructing HMM (Upper left, blue), the authors identify CMCPs in bacteria genomes and CRC related metagenomes and enriched CRC‐related CMCPs (Upper right, blue). They analyze sequence and structural similarity of hits (Lower left, green), test function with engineered EcN delivered to tumors in a mouse tumor model (Lower right, pink ...
Ziyu Wang   +12 more
wiley   +1 more source

Aetiological Significance of Infectious Stimuli in Kawasaki Disease

open access: yesFrontiers in Pediatrics, 2019
Kawasaki disease (KD) is a pediatric vasculitis syndrome that is often involves coronary artery lesions (e. g., coronary artery aneurysms). Although its causal factors and entire pathogenesis remain elusive, the available evidence indicates that the ...
Akihiro Nakamura   +3 more
doaj   +1 more source

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