Results 61 to 70 of about 7,221 (174)

The Antistaphylococcal Activity of Citropin 1.1 and Temporin A against Planktonic Cells and Biofilms Formed by Isolates from Patients with Atopic Dermatitis: An Assessment of Their Potential to Induce Microbial Resistance Compared to Conventional Antimicrobials

Pharmaceuticals, 2016
Staphylococcus aureus (SA) colonizes the vast majority of patients with atopic dermatitis (AD). Its resistance to antibiotics and ability to form biofilms are the main origins of therapeutic complications. Endogenous antimicrobial peptides (AMPs) exhibit
Malgorzata Dawgul, Wioletta Baranska-Rybak, Lidia Piechowicz, Marta Bauer, Damian Neubauer, Roman Nowicki, Wojciech Kamysz   +6 more
doaj   +1 more source

egc Superantigens Impair Monocytes/Macrophages Inducing Cell Death and Inefficient Activation

Frontiers in Immunology, 2020
Bacterial superantigens (SAgs) are enterotoxins that bind to MHC-II and TCR molecules, activating as much as 20% of the T cell population and promoting a cytokine storm which enhances susceptibility to endotoxic shock, causing immunosuppression, and ...
Sofia Noli Truant, Sofia Noli Truant, Mauricio C. De Marzi, Mauricio C. De Marzi, Mauricio C. De Marzi, Mauricio C. De Marzi, María B. Sarratea, María B. Sarratea, María B. Antonoglou, María B. Antonoglou, Ana P. Meo, Laura V. Iannantuono López, Laura V. Iannantuono López, María J. Fernández Lynch, María J. Fernández Lynch, Marcos Todone, Marcos Todone, Marcos Todone, Emilio L. Malchiodi, Emilio L. Malchiodi, Marisa M. Fernández, Marisa M. Fernández   +21 more
doaj   +1 more source

Severe generalized pustular psoriasis complicated with staphylococcal toxic shock syndrome treated with spesolimab and antibiotics

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Spyridon Gkalpakiotis, Jan Hugo, Natalie Michalik, Robert Zajicek, Cecilie Stonova, Bohumil Bakalar   +5 more
wiley   +1 more source

Constitutional symptoms and response to Penicillin G in erysipelas and cellulitis – a monocentric, retrospective, explorative study

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 6, Page 746-754, June 2026.
Summary Background: Erysipelas, caused by streptococci, should be treated with penicillin, while uncomplicated cellulitis (phlegmon), often caused by Staphylococcus aureus, requires penicillinase‐resistant beta‐lactam antibiotics, which have a higher risk of adverse effects. Distinguishing between these infections is important.
Helena Schieffers, Cord Sunderkötter
wiley   +1 more source

A Pilot qPCR Analysis of Superantigen-producing MRSA Presence in the Ear and Nose

Journal of Pure and Applied Microbiology
Microbial migration between the ear, throat, and nasal cavities can aggravate certain otorhinolaryngological conditions. For instance, Staphylococcus aureus colonization in the middle ear increases otitis media occurrence, while nasal colonization can ...
Percy David Papa Akuetteh, Lanlan Jin, Zihang Li, Tianyu Jiang, Haoqing Zhu, Kunbo Yuan, Mengting Xu, Shihan Du, Samuel Ken-En Gan   +8 more
doaj   +1 more source

Causes of Kawasaki Disease—From Past to Present

Frontiers in Pediatrics, 2019
Kawasaki disease (KD) is a multisystem vasculitis that primarily affects the coronary arteries of young children. The causes of KD remain a mystery. It is suspected that some sort of infectious agent is involved because KD has epidemicity and seasonality.
Satoru Nagata
doaj   +1 more source

Two homologous sequences of Grp78 and HSP70 represent tumor antigens shared with streptococcal superantigens in eliciting an antitumor immune response: an immunoinformatic investigation

Frontiers in Immunology
Bacteria-based therapies have gained increasing attention as novel immunotherapeutic approaches against tumors. Among them, bacteria producing superantigen (SAg) toxins are considered particularly effective due to their ability to induce potent ...
Paola Finotti
doaj   +1 more source

Isolation, Cloning, and Expression of Streptococcus dysgalactiae Subspecies Superantigen by SDS-PAGE in Psoriasis Patients

مجله دانشگاه علوم پزشکی گرگان, 2022
Background and Objective: Streptococci are Gram-positive and anaerobic bacteria that are isolated from different sources. These bacteria are capable of producing superantigens, toxins, and biologically-active substances and are therefore very important ...
Kumarss Amini, Ali Habbadi
doaj  

Presence of Group A streptococcus frequently assayed virulence genes in invasive disease: a systematic review and meta-analysis

Frontiers in Cellular and Infection Microbiology
IntroductionIt is currently unclear what the role of Group A streptococcus (GAS) virulence factors (VFs) is in contributing to the invasive potential of GAS.
Kimona Rampersadh, M. Taariq Salie, Kelin C. Engel, Clinton Moodley, Clinton Moodley, Liesl J. Zühlke, Liesl J. Zühlke, Mark E. Engel, Mark E. Engel   +8 more
doaj   +1 more source

Staphylococcal Superantigen (TSST-1) Mutant Analysis Reveals that T Cell Activation Is Required for Biological Effects in the Rabbit Including the Cytokine Storm

Toxins, 2010
Staphylococcal superantigens (sAgs), such as toxic shock syndrome toxin 1 (TSST-1), induce massive cytokine production, which may result in toxic shock syndrome (TSS) and sepsis.
Norbert Stich, Martina Waclavicek, Nina Model, Martha M. Eibl   +3 more
doaj   +1 more source