Results 51 to 60 of about 13,743 (223)

Blocking Superantigen-Mediated Diseases: Challenges and Future Trends

Journal of Immunology Research
Superantigens are virulence factors secreted by microorganisms that can cause various immune diseases, such as overactivating the immune system, resulting in cytokine storms, rheumatoid arthritis, and multiple sclerosis.
Pengbo Wang, Zina Fredj, Hongyong Zhang, Guoguang Rong, Sumin Bian, Mohamad Sawan   +5 more
doaj   +1 more source

Staphylococcal Virulence Factors on the Skin of Atopic Dermatitis Patients

mSphere, 2019
Staphylococcus aureus is the leading cause of skin and soft tissue infections, bacteremia, infective endocarditis, osteoarticular, pleuropulmonary, and device-related infections. Virulence factors secreted by S.
Mary C. Moran, Michael P. Cahill, Matthew G. Brewer, Takeshi Yoshida, Sara Knowlden, Nelissa Perez-Nazario, Patrick M. Schlievert, Lisa A. Beck   +7 more
doaj   +1 more source

S. aureus virulence factors decrease epithelial barrier function and increase susceptibility to viral infection

Microbiology Spectrum, 2023
Individuals with atopic dermatitis (AD) are highly colonized by Staphylococcus aureus and are more susceptible to severe viral complications. We hypothesized that S.
Mary C. Moran, Matthew G. Brewer, Patrick M. Schlievert, Lisa A. Beck   +3 more
doaj   +1 more source

Molecular Genetic Typing of Staphylococcus aureus from Cows, Goats, Sheep, Rabbits and Chickens [PDF]

, 2006
End of project reportsS. aureus can also cause a number of infections in animals such as tick-associated pyaemia in lambs, staphylococcosis in rabbits, septicaemia, abscesses and chondronecrosis in chickens and pneumonia and osteomyelitis complex in ...
Hartigan, Patrick J., Meaney, William J, Smyth, Cyril James, Smyth, Davida S.   +3 more
core  

Low anti-staphylococcal IgG responses in granulomatosis with polyangiitis patients despite long-term Staphylococcus aureus exposure [PDF]

, 2015
Chronic nasal carriage of the bacterium Staphylococcus aureus in patients with the autoimmune disease granulomatosis with polyangiitis (GPA) is a risk factor for disease relapse.
Arends, J.P.A. (Jan), Buist, G. (Girbe), De Goffau, M.C. (Marcus C.), Dijl, J.M. (Jan Maarten), Glasner, C. (Corinna), Heeringa, P. (Peter), Kallenberg, C.G.M. (Cees G. M.), Kampinga, G.A. (Greetje), Koedijk, D.G.A.M. (Denny), Neef, J. (Jolanda), Omansen, T.F. (Till F.), Raangs, E.C. (Erwin C.), Rossen, J.W. (John), Rutgers, A. (Abraham), Stegeman, C.A., Stobernack, T. (Tim), Tavakol, M. (Mehri), Van Timmeren, M.M. (Mirjan M.), Wamel, W.J.B. (Willem) van   +18 more
core   +1 more source

Divergent Paths: A Comprehensive Review of Mechanisms and Clinical Implications in Atopic Dermatitis and Psoriasis

Allergy, EarlyView.
ABSTRACT Atopic dermatitis and psoriasis are two common cutaneous chronic inflammatory diseases. Although they share similar immunological mechanisms, their clinical implications in the patient are different. This review compares both diseases from different points of view such as genetics, natural history, triggers of disease, and skin barrier defects
Tali Czarnowicki, Kazunari Sugita, Zenas Yiu, Sandra Díez‐Ribas, Irene Garcia‐Jimenez, Emma Guttman‐Yassky, Luis F. Santamaria‐Babí   +6 more
wiley   +1 more source

Allergens, germs and asthma [PDF]

, 2015
Objective To explore asthma pathogenesis using data from upper and lower airways. Data Source English-language papers on human asthma and nasal polyp subjects from 1990 onwards.
Scadding, GK
core  

Keratinocyte Priming by Staphylococcus aureus Reduces HSV‐1 Susceptibility

Allergy, EarlyView.
ADEH+ patients have a reduced microbial diversity with increased S. aureus and S. epidermidis colonization compared to ADEH− and healthy controls. Heat‐killed S. aureus reduced HSV‐1 susceptibility and release of infectious progeny virus in a keratinocyte in vitro model. Heat‐killed S.
Phila Cara Baumann, Rebecca Pospich, Katinka Döhner, Ilona Klug, Julio Cesar Villalvazo Guerrero, Jan Hartmann, Inken Harder, Wolfgang Lieb, Barbara Kind, Andreas Kleinheinz, Susanne Abraham, Matthias Augustin, Elke Weisshaar, Jochen Schmitt, Stephan Weidinger, Beate Sodeik, Thomas Werfel, Lennart M. Roesner, Stephan Traidl, The TREATgermany Study Group   +19 more
wiley   +1 more source

Characterization of Human Type C Enterotoxin Produced by Clinical S. epidermidis Isolates

Toxins, 2018
Staphylococcal Enterotoxins (SEs) are superantigens (SAg) originally produced by S. aureus, but their presence in coagulase negative staphylococci (CNS) has long been suspected.
Chimène Nanoukon, Dissou Affolabi, Daniel Keller, Rodrigue Tollo, Philippe Riegel, Lamine Baba-Moussa, Gilles Prévost   +6 more
doaj   +1 more source

Constitutional symptoms and response to Penicillin G in erysipelas and cellulitis – a monocentric, retrospective, explorative study

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background: Erysipelas, caused by streptococci, should be treated with penicillin, while uncomplicated cellulitis (phlegmon), often caused by Staphylococcus aureus, requires penicillinase‐resistant beta‐lactam antibiotics, which have a higher risk of adverse effects. Distinguishing between these infections is important.
Helena Schieffers, Cord Sunderkötter
wiley   +1 more source