Results 51 to 60 of about 9,440 (204)

Microbiota Signatures in Early Life and Their Association With Food Allergy: A Systematic Review

Allergy, EarlyView.
ABSTRACT Food allergy (FA) is increasing worldwide, and early life may be a critical window for immune training. We systematically reviewed observational human studies linking early‐life microbiota (infant, maternal, environmental, or extraintestinal) profiled using culture‐based and/or culture‐independent methods (including sequencing‐based approaches)
Eduard Flores Ventura, Jeremy Corriger, Hélène Omer, Marie Bodinier, Dirk Haller, Tomer Hertz, Martin Larsen, Maria Carmen Collado   +7 more
wiley   +1 more source

Characterization of Staphylococcus aureus Enterotoxin L [PDF]

, 2003
Staphylococcus aureus causes a wide variety of diseases. Major virulence factors of this organism include enterotoxins (SEs) that cause both food poisoning and toxic shock syndrome.
Bohach, G. A., Gutierrez, J. A., Orwin, Paul M., Fitzgerald, Ross; id_orcid, Fitzgerald, J. Ross, Schlievert, Patrick M., Orwin, P. M., Bohach, Gregory A., Schlievert, P. M., Leung, D. Y. M., Leung, Donald Y. M., Gutierrez, Juan A.   +11 more
core   +1 more source

IgE‐Binding Bacterial Components Not Yet Documented in the Allergen Databases and Their Allergenic Mechanisms: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT Among bacteria that are associated with the development and/or exacerbation of allergic/atopic diseases, several have been described to produce IgE‐binding components. However, only one bacterial protein, Bac s 1, is currently listed in the official database of the World Health Organization/International Union of Immunological Societies (WHO ...
Uta Jappe, Marua Abu Risha, Ioana Agache, Claus Bachert, Barbara Bröker, Riccardo Castagnoli, Gabriele Gadermaier, Richard E. Goodman, Amir Guemari, Christiane Hilger, Alain Jacquet, Sabine Kespohl, Ludger Klimek, Annette Kuehn, Jonas Lidholm, Vera Mahler, Markus Ollert, Thomas A. Platts‐Mills, Monika Raulf, Peter Schmid‐Grendelmeier, Frieder Schmiedeke, Marianne van Hage, Joana Vitte, Josefina Zakzuk, Anna Pomés   +24 more
wiley   +1 more source

Streptococcal superantigens: Categorization and clinical associations

, 2014
Superantigens are key virulence factors in the immunopathogenesis of invasive disease caused by group A streptococcus. These protein exotoxins have also been associated with severe group C and group G streptococcal infections.
Commons, Robert R.J., John D. Fraser, Nigel Curtis, Smeesters, Pierre, Pierre R. Smeesters, Fraser, John J.D., Robins-Browne, Roy, Robert J. Commons, Thomas Proft, Roy Robins-Browne, Curtis, Nigel, Proft, Thomas   +11 more
core   +1 more source

Superantigens in Human Disease

, 1999
Superantigens have been implicated in a wide variety of human diseases. Yet, solid evidence for their role in pathogenesis is available only for Toxic Shock Syndrome and a few other conditions.
Posnett, DN, Bernal, A, Proft, Thomas, Fraser, John   +3 more
core   +1 more source

Staphylococcal Superantigens Stimulate Epithelial Cells through CD40 To Produce Chemokines

mBio, 2019
Mucosal and skin tissues form barriers to infection by most bacterial pathogens. Staphylococcus aureus causes diseases across these barriers in part dependent on the proinflammatory properties of superantigens.
Patrick M. Schlievert, Michael P. Cahill, Bruce S. Hostager, Amanda J. Brosnahan, Aloysius J. Klingelhutz, Francoise A. Gourronc, Gail A. Bishop, Donald Y. M. Leung   +7 more
doaj   +1 more source

Mast Cells in Host Defense Against Cutaneous Staphylococcus aureus Infection

Immunology &Cell Biology, EarlyView.
Impact of S. aureus epicutaneous sensitization models on mast cell function in vivo. D. farinae and Staphylococcal enterotoxin B (SEB) activate Trpv1+ Tac1+ nociceptors to trigger the release of substance P (SP), which promotes mast cell degranulation through Mrgprb2. S.
Hannah Dychtenberg, Carly Kadonoff, Bailey Lehnert, Priyanka Pundir   +3 more
wiley   +1 more source

Temporal and Racial Differences Associated with Atopic Dermatitis Staphylococcus aureus and Encoded Virulence Factors

mSphere, 2016
Atopic dermatitis (AD) is an inflammatory skin condition strongly associated with Staphylococcus aureus colonization and infection. S. aureus strains shift in populations in ~10-year intervals depending on virulence factors. Shifts in S. aureus virulence
Joseph A. Merriman, Elizabeth A. Mueller, Michael P. Cahill, Lisa A. Beck, Amy S. Paller, Jon M. Hanifin, Peck Y. Ong, Lynda Schneider, Denise C. Babineau, Gloria David, Alexandre Lockhart, Keli Artis, Donald Y. M. Leung, Patrick M. Schlievert   +13 more
doaj   +1 more source

Immune Consequences of Metabolic Syndrome and Its Treatment: A Cytokine Perspective

Immunology, EarlyView.
Peripheral blood mononuclear cells (PBMCs) from individuals with metabolic syndrome (MetS) who were not using glucose‐and/or lipid lowering medication (GLLM) exhibited a broader cytokine production profile after in vitro antigen‐specific stimulation than PBMCs from individuals with MetS using such medications and from healthy donors.
Isabela Ghetti Macedo Isaac, Carolina do Prado Servian, Fernanda de Oliveira Feitosa de Castro, João Lucas Lima Calandrini de Azevedo, Ronaldo Moraes Preto, Miriam Leandro Dorta, Daniela Espíndola Antunes, Simone Gonçalves Fonseca   +7 more
wiley   +1 more source

Cooperative activation of TCRs by enterotoxin superantigens.

, 1998
Disponible gratuitement sur le site de l'éditeur. http://www.jimmunol.org/cgi/pmidlookup?view=long&pmid=9834088International audienceStaphylococcus enterotoxin superantigens are potent T cell activators.
Niedergang, Florence, Dautry-Varsat, Alice, Alcover, Andrés   +2 more
core   +1 more source