Results 31 to 40 of about 9,440 (204)

Comparison of Transcriptional Signatures of Three Staphylococcal Superantigenic Toxins in Human Melanocytes

open access: yesBiomedicines, 2022
Staphylococcus aureus, a gram-positive bacterium, causes toxic shock through the production of superantigenic toxins (sAgs) known as Staphylococcal enterotoxins (SE), serotypes A-J (SEA, SEB, etc.), and toxic shock syndrome toxin-1 (TSST-1).
Nabarun Chakraborty   +11 more
doaj   +1 more source

Phenotypes and Virulence among Staphylococcus aureus USA100, USA200, USA300, USA400, and USA600 Clonal Lineages

open access: yesmSphere, 2016
Staphylococcus aureus diseases affect ~500,000 individuals per year in the United States. Worldwide, the USA100, USA200, USA400, and USA600 lineages cause many of the life-threatening S.
Jessica M. King   +4 more
doaj   +1 more source

Superantigens: Gazing into the crystal ball [PDF]

open access: yes, 1995
The recently determined crystal structures of complexes between bacterial toxin ‘superantigens’ and MHC class II molecules shed light on the nature of the interactions between these two ...
Hsu, Ping-Ning   +3 more
core   +1 more source

Aetiological Significance of Infectious Stimuli in Kawasaki Disease

open access: yesFrontiers in Pediatrics, 2019
Kawasaki disease (KD) is a pediatric vasculitis syndrome that is often involves coronary artery lesions (e. g., coronary artery aneurysms). Although its causal factors and entire pathogenesis remain elusive, the available evidence indicates that the ...
Akihiro Nakamura   +3 more
doaj   +1 more source

Superantigen architecture: Functional decoration on a conserved scaffold [PDF]

open access: yes, 2007
A defining and consistent feature of the bacterial superantigens from Staphylococcus aureus and Streptococcus pyogenes is their strongly conserved three-dimensional structure.
Arcus, Vickery L., Baker, Edward N.
core  

Soluble T Cell Receptor Vβ Domains Engineered for High-Affinity Binding to Staphylococcal or Streptococcal Superantigens

open access: yesToxins, 2014
Staphylococcus aureus and group A Streptococcus secrete a collection of toxins called superantigens (SAgs), so-called because they stimulate a large fraction of an individual’s T cells.
Preeti Sharma   +2 more
doaj   +1 more source

Microbial‐Metabolite Signatures Are Associated With Glucocorticoid Responsiveness in Chronic Rhinosinusitis With Nasal Polyps

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Patients with chronic rhinosinusitis with nasal polyps (CRSwNP) exhibit heterogeneous responses to oral glucocorticoids (GCs), but the biological basis of this variability remains unclear. Objective To identify gut microbiome‒plasma metabolomic signatures associated with GC responsiveness in CRSwNP patients and to compare their ...
Ying‐Ying Zhang   +7 more
wiley   +1 more source

Interplay between superantigens and the immune system

open access: yes, 1993
Superantigens interact with the immune system by binding to major histocompatibility complex (MHG) class II proteins and activating T cells through the variable region of the T cell receptor β-chain.
Michael J Irwin, Nicholas R J Gascoigne
core   +1 more source

Current Views about the Inflammatory Damage Triggered by Bacterial Superantigens and Experimental Attempts to Neutralize Superantigen-Mediated Toxic Effects with Natural and Biological Products

open access: yesPathophysiology
Superantigens, i.e., staphylococcal enterotoxins and toxic shock syndrome toxin-1, interact with T cells in a different manner in comparison to conventional antigens.
Luigi Santacroce   +6 more
doaj   +1 more source

Microbiota in immune pathogenesis and the prospects for pre and probiotic dietetics in psoriasis

open access: yesBiomedical Research Journal, 2015
Psoriasis is a common autoimmune inflammatory disease wherein pathogenesis is advanced by fundamental genetic predisposition/s in concert with environmental triggers.
Garima Pandey   +3 more
doaj   +1 more source

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