Results 21 to 30 of about 7,221 (174)

Staphylococcal Enterotoxins

Toxins, 2010
Staphylococcus aureus (S. aureus) is a Gram positive bacterium that is carried by about one third of the general population and is responsible for common and serious diseases.
Victor E. Reyes, Ellen J. Beswick, Irina V. Pinchuk   +2 more
doaj   +1 more source

Viral Superantigens [PDF]

Mikrobiyoloji Bulteni, 2016
Superantigens (SAgs) are microbial proteins produced by various microorganisms that elicit excessive and strong stimulation of T cells via an unconventional mechanism. They cause polyclonal activation of T cells in a non-specific manner, by binding to a particular variable-beta (Vβ) chain of T-cell receptor (TCR) and MHC class II molecule, in ...
openaire   +2 more sources

Comparison of Transcriptional Signatures of Three Staphylococcal Superantigenic Toxins in Human Melanocytes

Biomedicines, 2022
Staphylococcus aureus, a gram-positive bacterium, causes toxic shock through the production of superantigenic toxins (sAgs) known as Staphylococcal enterotoxins (SE), serotypes A-J (SEA, SEB, etc.), and toxic shock syndrome toxin-1 (TSST-1).
Nabarun Chakraborty, Seshamalini Srinivasan, Ruoting Yang, Stacy-Ann Miller, Aarti Gautam, Leanne J. Detwiler, Bonnie C. Carney, Abdulnaser Alkhalil, Lauren T. Moffatt, Marti Jett, Jeffrey W. Shupp, Rasha Hammamieh   +11 more
doaj   +1 more source

Phenotypes and Virulence among Staphylococcus aureus USA100, USA200, USA300, USA400, and USA600 Clonal Lineages

mSphere, 2016
Staphylococcus aureus diseases affect ~500,000 individuals per year in the United States. Worldwide, the USA100, USA200, USA400, and USA600 lineages cause many of the life-threatening S.
Jessica M. King, Katarina Kulhankova, Christopher S. Stach, Bao G. Vu, Wilmara Salgado-Pabón   +4 more
doaj   +1 more source

Aetiological Significance of Infectious Stimuli in Kawasaki Disease

Frontiers in Pediatrics, 2019
Kawasaki disease (KD) is a pediatric vasculitis syndrome that is often involves coronary artery lesions (e. g., coronary artery aneurysms). Although its causal factors and entire pathogenesis remain elusive, the available evidence indicates that the ...
Akihiro Nakamura, Kazuyuki Ikeda, Kenji Hamaoka, Kenji Hamaoka   +3 more
doaj   +1 more source

Soluble T Cell Receptor Vβ Domains Engineered for High-Affinity Binding to Staphylococcal or Streptococcal Superantigens

Toxins, 2014
Staphylococcus aureus and group A Streptococcus secrete a collection of toxins called superantigens (SAgs), so-called because they stimulate a large fraction of an individual’s T cells.
Preeti Sharma, Ningyan Wang, David M. Kranz   +2 more
doaj   +1 more source

Engineering Human Donor Derived Germinal Center‐Like Organoids (GCLOs) for Studying Immune Response to Vaccination

Advanced Science, EarlyView.
We bioengineered a new approach methodology of generating Germinal Center Organoids that self‐organize from human blood‐derived immune cells. These immune organoids reproduce key features of humoral immunity, IgG production, and plasmablast emergence.
Bhumi Suthar, Carlos Gomez, Giancarlo Asencio, Suresh Pallikkuth, Ashutosh Agarwal   +4 more
wiley   +1 more source

Current Views about the Inflammatory Damage Triggered by Bacterial Superantigens and Experimental Attempts to Neutralize Superantigen-Mediated Toxic Effects with Natural and Biological Products

Pathophysiology
Superantigens, i.e., staphylococcal enterotoxins and toxic shock syndrome toxin-1, interact with T cells in a different manner in comparison to conventional antigens.
Luigi Santacroce, Skender Topi, Ioannis Alexandros Charitos, Roberto Lovero, Paolo Luperto, Raffaele Palmirotta, Emilio Jirillo   +6 more
doaj   +1 more source

Microbiota in immune pathogenesis and the prospects for pre and probiotic dietetics in psoriasis

Biomedical Research Journal, 2015
Psoriasis is a common autoimmune inflammatory disease wherein pathogenesis is advanced by fundamental genetic predisposition/s in concert with environmental triggers.
Garima Pandey, Abhay Kumar Pandey, S S Pandey, B L Pandey   +3 more
doaj   +1 more source

Inhibition of Toxic Shock Syndrome-Associated Staphylococcus aureus by Probiotic Lactobacilli

Microbiology Spectrum, 2023
Staphylococcus aureus is a human pathogen with many infections originating on mucosal surfaces. One common group of S. aureus is the USA200 (CC30) clonal group, which produces toxic shock syndrome toxin-1 (TSST-1). Many USA200 infections occur on mucosal
Patrick M. Schlievert, Adriana V. Gaitán, Samuel H. Kilgore, Amy L. Roe, Johanna Maukonen, Liisa Lehtoranta, Donald Y. M. Leung, Daniel S. Marsman   +7 more
doaj   +1 more source