Results 11 to 20 of about 562,973 (359)

Selective superoxide generation within mitochondria by the targeted redox cycler MitoParaquat [PDF]

, 2015
Superoxide is the proximal reactive oxygen species (ROS) produced by the mitochondrial respiratory chain and plays a major role in pathological oxidative stress and redox signaling.
Aksentijević, Dunja, Bright, Thomas P., Cocheme, Helena M., Gawel, Justyna M., Hartley, Richard C., James, Andrew M., Murphy, Michael P., Prime, Tracy A., Qiang, He, Robb, Ellen L., Senn, Hans M., Shattock, Michael J., Shchepinova, Maria M., Stewart, Tessa S.   +13 more
core   +1 more source

Structural Evidence for a Copper-Bound Carbonate Intermediate in the Peroxidase and Dismutase Activities of Superoxide Dismutase [PDF]

, 2012
Copper-zinc superoxide dismutase (SOD) is of fundamental importance to our understanding of oxidative damage. Its primary function is catalysing the dismutation of superoxide to O2 and H2O2. SOD also reacts with H2O2, leading to the formation of a strong
Luis Eduardo Soares Netto, Michael A. Hough, Richard W. Strange, S. Samar Hasnain, Svetlana V. Antonyuk   +4 more
core   +9 more sources

Influence of hyperhomocysteinemia on the cellular redox state - Impact on homocysteine-induced endothelial dysfunction [PDF]

, 2003
Hyperhomocysteinemia is an independent risk factor for the development of atherosclerosis. An increasing body of evidence has implicated oxidative stress as being contributory to homocysteines deleterious effects on the vasculature.
Adachi T, Andersson A, Bagi Z, Bellamy MF, Chambers JC, Chambers JC, Chao CL, Flohé L, Forgione MA, Guttormsen AB, Huang R-FS, Kanani PM, Karlsson K, Lang D, Lentz SR, Mansoor MA, Mansoor MA, Mansoor MA, Mansoor MA, O'Donnell VB, Outinen PA, Pritchard, Rubbo H, Tawakol A, Ungvari Z, Weiss N, Wilcken DE, Woo KS, Zhang F, Zhang X   +29 more
core   +1 more source

Nitric oxide availability is increased in contracting skeletal muscle from aged mice, but does not differentially decrease muscle superoxide [PDF]

, 2014
Reactive oxygen and nitrogen species have been implicated in the loss of skeletal muscle mass and function that occurs during aging. Nitric oxide (NO) and superoxide are generated by skeletal muscle and where these are generated in proximity their ...
A. McArdle, Ali, Balon, Beckman, Braga, Broome, Chang, Close, Cobley, Cortese-Krott, Dubuisson, Erusalimsky, Grozdanovic, Hirschfield, Kobzik, Kojima, Lau, Leiter, Lexell, M.J. Jackson, McConell, Melov, Morley, Muller, Murrant, Nyberg, Palomero, Palomero, Pattwell, Pearson, Porter, Pulliam, Pye, Radi, Reid, Richmonds, Ropelle, Ryall, Sakellariou, Sakellariou, Samengo, Sasaki, Sastre, Sawada, Shefer, Sohal, Song, T. Pearson, Tidball, Trujillo, Vasilaki, Vasilaki, Vasilaki, Vasilaki, Wang, Young   +55 more
core   +2 more sources

Oxidative stress markers in intestinal mucosa of Tunisian inflammatory bowel disease patients

The Saudi Journal of Gastroenterology, 2013
Background / Aims: Inflammatory bowel diseases (IBDs), Crohn′s disease (CrD) and ulcerative colitis (UC), are chronic gastrointestinal inflammatory disorders.
Dorra Bouzid, Bochra Gargouri, Riadh Ben Mansour, Ali Amouri, Nabil Tahri, Saloua Lassoued, Hatem Masmoudi   +6 more
doaj   +1 more source

The crystal structure of superoxide dismutase from Plasmodium falciparum [PDF]

, 2006
Background: Superoxide dismutases (SODs) are important enzymes in defence against oxidative stress. In Plasmodium falciparum, they may be expected to have special significance since part of the parasite life cycle is spent in red blood cells where the ...
Boucher, Ian W., Brannigan, James A., Brzozowski, Andrzej M., Kyes, Sue A., Schnick, Claudia, Smith, Derek J., Wilkinson, Anthony J.   +6 more
core   +3 more sources

Inhibition of Aflatoxin Production by Paraquat and External Superoxide Dismutase in Aspergillus flavus

Toxins, 2019
Aflatoxin contamination of crops is a worldwide problem, and elucidation of the regulatory mechanism of aflatoxin production, for example relative to the oxidative⁻antioxidative system, is needed. Studies have shown that oxidative stress induced by
Tomohiro Furukawa, Shohei Sakuda
doaj   +1 more source

Sensitive superoxide detection in vascular cells by the new chemiluminescence dye L-012 [PDF]

, 1999
The detection superoxide production in vascular cells is usually limited by a low sensitivity of available assays, We tested the applicability of the luminol derivate L-012 {[}8-amino-5-chloro-7-phenylpyridol{[}3,4-d]pyridazine-l,4(2H,3H)dione] to ...
Gloe, Torsten, Keller, Matthias, Pohl, Ulrich, Schoenafinger, Karl, Sohn, Hae-Young   +4 more
core   +1 more source

Dark biological superoxide production as a significant flux and sink of marine dissolved oxygen [PDF]

, 2020
© The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Sutherland, K. M., Wankel, S. D., & Hansel, C. M.
Hansel, Colleen M., Sutherland, Kevin M., Wankel, Scott D.   +2 more
core   +1 more source

Fluorescent monitoring of copper-occupancy in His-ended catalytic oligo-peptides

Communicative & Integrative Biology, 2016
Controlled generation of reactive oxygen species (ROS) is widely beneficial to various medical, environmental, and agricultural studies. As inspired by the functional motifs in natural proteins, our group has been engaged in development of catalytically ...
Reina Inokuchi, Tomonori Kawano
doaj   +1 more source