Results 11 to 20 of about 526,315 (198)

Zinc Supplementation Combats Tuberculosis by Reverting Back to Normal Compartmentalized State of Iron and Hence Increasing Blood Hemoglobin Concentration [PDF]

Indian Journal of Medical Biochemistry, 2023
Aim and background: To acquire iron (Fe), Mycobacterium tuberculosis (Mtb) expresses high-affinity Fe+3-specific siderophores for scavenging Fe from host insoluble and protein-bound iron-like transferrin, lactoferrin, ferritin, and hemoglobin−haptoglobin.
Dipak Kumar Chattopadhyay
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Examining the Antioxidant and Superoxide Radical Scavenging Activity of Anise, (Pimpinella anisum L. Seeds), Esculetin, and 4-Methyl-Esculetin Using X-ray Diffraction, Hydrodynamic Voltammetry and DFT Methods

Pharmaceuticals, 2023
Pimpinella anisum L., or anise, is a plant that, besides its nutritional value, has been used in traditional medical practices and described in many cultures in the Mediterranean region. A possible reason for anise’s therapeutic value is that it contains
Miriam Rossi, Francesco Caruso, Natalie Thieke, Stuart Belli, Alana Kim, Elisabetta Damiani, Camilla Morresi, Tiziana Bacchetti   +7 more
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Bortezomib is an effective enhancer for chemical probe-dependent superoxide detection

Frontiers in Medicine, 2022
Various chemical probes for the detection of reactive oxygen species have been developed to examine oxidative stress associated with different pathologies.
Misaki Matsumoto, Hikari Sawada, Kazumi Iwata, Masakazu Ibi, Nozomi Asaoka, Masato Katsuyama, Kaori Shintani-Ishida, Hiroshi Ikegaya, Shigehiko Takegami, Atsushi Umemura, Chihiro Yabe-Nishimura   +10 more
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Soybean-Derived Tripeptide Leu–Ser–Trp (LSW) Protects Human Vascular Endothelial Cells from TNFα-Induced Oxidative Stress and Inflammation via Modulating TNFα Receptors and SIRT1

Foods, 2022
Soybean is a rich source of high-quality proteins and an excellent food source of bioactive peptides. A tripeptide, Leu–Ser–Trp (LSW), was previously identified from soybean as an angiotensin-converting enzyme inhibitory peptide.
Hongbing Fan, Khushwant S. Bhullar, Zihan Wang, Jianping Wu   +3 more
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Early life stress induces dysregulation of the heme pathway in adult mice

Physiological Reports, 2021
Early life stress (ELS) is associated with cardiovascular disease (CVD) risk in adulthood, but the underlying vascular mechanisms are poorly understood.
Yasminye D. Pettway, Thomas H. Neder, Dao H. Ho, Brandon M. Fox, Mariah Burch, Jackson Colson, Xiaofen Liu, Cailin E. Kellum, Kelly A. Hyndman, Jennifer S. Pollock   +9 more
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The Labile Iron Pool Reacts Rapidly and Catalytically with Peroxynitrite

Biomolecules, 2021
While investigating peroxynitrite-dependent oxidation in murine RAW 264.7 macrophage cells, we observed that removal of the Labile Iron Pool (LIP) by chelation increases the intracellular oxidation of the fluorescent indicator H2DCF, so we concluded that
André Luís Condeles, José Carlos Toledo Junior   +1 more
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Functional interactions between NADPH oxidase 5 and actin

Frontiers in Cell and Developmental Biology, 2023
NADPH oxidase 5 (NOX5) is a transmembrane oxidative signaling enzyme which produces superoxide in response to intracellular calcium flux. Increasing evidence indicates that NOX5 is involved in a variety of physiological processes as well as human disease,
Samantha M. Richter, Lilyanna C. Massman, Dennis J. Stuehr, Elizabeth A. Sweeny   +3 more
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EPR Study of KO₂ as a Source of Superoxide and ^•BMPO-OH/OOH Radical That Cleaves Plasmid DNA and Detects Radical Interaction with H₂S and Se-Derivatives

Antioxidants, 2021
Superoxide radical anion (O2•−) and its derivatives regulate numerous physiological and pathological processes, which are extensively studied. The aim of our work was to utilize KO2 as a source of O2•− and the electron paramagnetic resonance (EPR) spin ...
Anton Misak, Vlasta Brezova, Miroslav Chovanec, Karol Luspai, Muhammad Jawad Nasim, Marian Grman, Lenka Tomasova, Claus Jacob, Karol Ondrias   +8 more
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Cloning, Characteristics and Functional Analysis of Rabbit NADPH Oxidase 5

Frontiers in Physiology, 2016
Background: Nox5 was the last member of the Nox enzyme family to be identified. Functionally distinct from the other Nox isoforms, our understanding of its physiological significance has been hampered by the absence of Nox5 in mouse and rat genomes. Nox5
Feng Chen, Christiana Dimitropoulou, David Fulton   +2 more
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Oxidative Stress and Atopic Dermatitis

Antioxidants, 2020
Atopic dermatitis is a common chronic/chronically relapsing inflammatory skin disease, with increasing worldwide prevalence. Etiopathogenesis is complex and multifactorial, with a mix of genetic, immunological and environmental aspects.
Lucrezia Bertino, Fabrizio Guarneri, Serafinella Patrizia Cannavò, Marco Casciaro, Giovanni Pioggia, Sebastiano Gangemi   +5 more
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