Results 21 to 30 of about 318,307 (167)

Bortezomib is an effective enhancer for chemical probe-dependent superoxide detection

Frontiers in Medicine, 2022
Various chemical probes for the detection of reactive oxygen species have been developed to examine oxidative stress associated with different pathologies.
Misaki Matsumoto, Hikari Sawada, Kazumi Iwata, Masakazu Ibi, Nozomi Asaoka, Masato Katsuyama, Kaori Shintani-Ishida, Hiroshi Ikegaya, Shigehiko Takegami, Atsushi Umemura, Chihiro Yabe-Nishimura   +10 more
doaj   +1 more source

SARS-CoV-2 Infection after Effects: Multi-Organ Damage through Oxygen Radicals

Apollo Medicine, 2022
Introduction: SARS-CoV-2 respiratory infection leads to two-layered pathology in time (a) immediate pathology and recovery or fatal ending and (b) long periods of remission followed by unexplained clinical expressions involving one or more systems with ...
Debatosh Datta, Rajveer Singh, Ravichandiran Velayutham, Arka Bhattacharya, Ujjwayini Ray, Sarbani Dasgupta, Soma Dutta, Aditi Saha, Debabrata Roy, Srinika Ghosh, Somasundaram Arumugam, Pallab Datta, N K Ganguly   +12 more
doaj   +1 more source

Copper- and Zinc-containing Superoxide Dismutase Can Act as a Superoxide Reductase and a Superoxide Oxidase [PDF]

Journal of Biological Chemistry, 2000
The copper- and zinc-containing superoxide dismutase can catalyze the oxidation of ferrocyanide by O(2) as well as the reduction of ferricyanide by O(2). Thus, it can act as a superoxide dismutase (SOD), a superoxide reductase (SOR), and a superoxide oxidase (SOO).
S I, Liochev, I, Fridovich
openaire   +2 more sources

Neisseria gonorrhoeae Exposed to Sublethal Levels of Hydrogen Peroxide Mounts a Complex Transcriptional Response

mSystems, 2018
Neisseria gonorrhoeae mounts a substantial transcriptional program in response to hydrogen peroxide (HP), a prominent reactive oxygen species (ROS) encountered during infection.
Sarah J. Quillin, Adam J. Hockenberry, Michael C. Jewett, H Steven Seifert   +3 more
doaj   +1 more source

Constraints on superoxide mediated formation of manganese oxides

Frontiers in Microbiology, 2013
Manganese (Mn) oxides are among the most reactive sorbents and oxidants within the environment, where they play a central role in the cycling of nutrients, metals, and carbon.
Deric R. Learman, Bettina M. Voelker, Andrew S. Madden, Colleen M. Hansel   +3 more
doaj   +1 more source

Bioactive Secondary Metabolites of a Marine Bacillus sp. Inhibit Superoxide Generation and Elastase Release in Human Neutrophils by Blocking Formyl Peptide Receptor 1

Molecules, 2013
It is well known that overwhelming neutrophil activation is closely related to acute and chronic inflammatory injuries. Formyl peptide receptor 1 (FPR1) plays an important role in activation of neutrophils and may represent a potent therapeutic target in
Yin-Ting Huang, Tsong-Long Hwang, Pei-Jen Chung, Jimmy Kuo, Shun-Chin Yang, Wen-Yi Chang, Chwan-Fwu Lin   +6 more
doaj   +1 more source

COX4-1 promotes mitochondrial supercomplex assembly and limits reactive oxide species production in radioresistant GBM

Cell Stress, 2022
Glioblastoma (GBM) is a fatal disease with recurrences often associated with radioresistance. Although often effective at treating newly diagnosed GBM, increasing evidence suggests that radiotherapy-induced alterations in tumor metabolism promote GBM ...
Claudia R. Oliva, Md Yousuf Ali, Susanne Flor, Corinne E. Griguer   +3 more
doaj   +1 more source

Identification of a core set of rhizobial infection genes using data from single cell-types

Frontiers in Plant Science, 2015
Genome-wide expression studies on nodulation have varied in their scale from entire root systems to dissected nodules or root sections containing nodule primordia.
Da-Song eChen, Cheng-wu eLiu, Sonali eRoy, Donna eCousins, Nicola eStacey, Jeremy Dale Murray   +5 more
doaj   +1 more source

Role of Protons in Superoxide Reduction by a Superoxide Reductase Analogue [PDF]

Inorganic Chemistry, 2005
Superoxide reduction by thiolate-ligated [FeII(SMe2N4(tren))]+ (1) involves two proton-dependent steps and a single peroxide intermediate, [FeIII(SMe2N4(tren))(OOH)]+ (2). An external proton donor is required, ruling out mechanisms involving H+ or H-atom abstraction from the ligand N-H.
Roslyn M, Theisen, Julie A, Kovacs
openaire   +2 more sources

Action of the 4-Nitro-2-phenoximethanesulphonanilide (Nimesulide) on neutrophil chemotaxis and superoxide production

São Paulo Medical Journal
4-nitro-2-phenoximethanesulphonanilide (nimesulide) is a nonsteroidal anti-inflammatory agent that has been employed in the treatment of inflammatory diseases because of its specific actions on the inflammatory response mechanisms caused by injury.
Susana Beatriz Veríssimo de Mello, leda Maria Magalhães Laurindo, Wilson Cossermelli   +2 more
doaj   +1 more source