Results 21 to 30 of about 442,139 (308)
The Non-Specific Drp1 Inhibitor Mdivi-1 Has Modest Biochemical Antioxidant Activity
Antioxidants, 2022 Mitochondrial division inhibitor-1 (mdivi-1), a non-specific inhibitor of Drp1-dependent mitochondrial fission, is neuroprotective in numerous preclinical disease models.
Evan A. Bordt +3 more
doaj +1 more source
Cigarette Smoke Extract Produces Superoxide in Aqueous Media by Reacting with Bicarbonate
Toxics, 2021 The toxicity of cigarette smoke (CS) is largely attributed to its ability to generate reactive oxygen species (ROS). Reportedly, CS generates superoxide in cell culture systems by stimulating the cells to produce superoxide and through direct chemical ...
Jung-Min Park +8 more
doaj +1 more source
Sensors, 2022 Reactive oxygen species (ROS) are key drivers of biogeochemical cycling while also exhibiting both positive and negative effects on marine ecosystem health.
Kalina C. Grabb +5 more
doaj +1 more source
Sensitive superoxide detection in vascular cells by the new chemiluminescence dye L-012 [PDF]
, 1999 The detection superoxide production in vascular cells is usually limited by a low sensitivity of available assays, We tested the applicability of the luminol derivate L-012 {[}8-amino-5-chloro-7-phenylpyridol{[}3,4-d]pyridazine-l,4(2H,3H)dione] to ...
Sohn, Hae-Young +4 more
core +1 more source
Antioxidants, 2020 Previous studies have demonstrated that redox selenium compounds arrest cancer cell viability in vitro through their pro-oxidative activity by generating superoxide (O2•−).
Soni Khandelwal +4 more
doaj +1 more source
eNOS protects from atherosclerosis despite relevant superoxide production by the enzyme in apoE mice. [PDF]
, 2012 All three nitric oxide synthase (NOS) isoforms are expressed in atherosclerotic plaques. NOS enzymes in general catalyse NO production. However, under conditions of substrate and cofactor deficiency, the enzyme directly catalyse superoxide formation ...
Sabine Grüner +27 more
core +2 more sources
Superoxide Dismutases and Superoxide Reductases
Chemical Reviews, 2014 Superoxide, O2•–, is formed in all living organisms that come in contact with air, and, depending upon its biological context, it may act as a signaling agent, a toxic species, or a harmless intermediate that decomposes spontaneously. Its levels are limited in vivo by two different types of enzymes, superoxide reductase (SOR) and superoxide dismutase ...
Sheng, Yuewei +6 more
openaire +2 more sources
Superoxide-Mediated Extracellular Mercury Reduction by Aerobic Marine Bacterium Alteromonas sp. KD01
, 2023 Microbial reduction plays a crucial role in Hg redox and the global cycle. Although intracellular Hg(II) reduction mediated by MerA protein is well documented, it is still unclear whether or how bacteria reduce Hg(II) extracellularly without its ...
Yanbin Li (1395286) +10 more
core +1 more source
Cloning, Characteristics and Functional Analysis of Rabbit NADPH Oxidase 5
Frontiers in Physiology, 2016 Background: Nox5 was the last member of the Nox enzyme family to be identified. Functionally distinct from the other Nox isoforms, our understanding of its physiological significance has been hampered by the absence of Nox5 in mouse and rat genomes. Nox5
Feng Chen +2 more
doaj +1 more source
Reaction of superoxide radicals with glycosaminoglycan chloramides: a kinetic study. [PDF]
, 2013 Hypochlorous acid and its acid-base counterpart, hypochlorite ions, produced under inflammatory conditions, may produce chloramides of glycosaminoglycans, perhaps through the binding of myeloperoxidase directly to the glycosaminoglycans.
Parsons, BJ +7 more
core +1 more source