Results 41 to 50 of about 442,139 (308)

Evidence that inhibition of phorbol ester-induced superoxide anion formation by cyclosporin A in phagocytes is not mediated by direct inhibition of protein kinase C [PDF]

open access: yes, 1994
Cyclosporin A (CsA) has been reported to inhibit phorbol myristate acetate (PMA)-induced superoxide anion (O2-) formation in human neutrophils and murine macrophages.
Grünbaum, L.   +4 more
core   +1 more source

SARS-CoV-2 Infection after Effects: Multi-Organ Damage through Oxygen Radicals

open access: yesApollo Medicine, 2022
Introduction: SARS-CoV-2 respiratory infection leads to two-layered pathology in time (a) immediate pathology and recovery or fatal ending and (b) long periods of remission followed by unexplained clinical expressions involving one or more systems with ...
Debatosh Datta   +12 more
doaj   +1 more source

Neisseria gonorrhoeae Exposed to Sublethal Levels of Hydrogen Peroxide Mounts a Complex Transcriptional Response

open access: yesmSystems, 2018
Neisseria gonorrhoeae mounts a substantial transcriptional program in response to hydrogen peroxide (HP), a prominent reactive oxygen species (ROS) encountered during infection.
Sarah J. Quillin   +3 more
doaj   +1 more source

Uremic concentrations of guanidino compounds inhibit neutrophil superoxide production [PDF]

open access: yes, 2001
Uremic concentrations of guanidino compounds inhibit neutrophil superoxide production.BackgroundIn Uremia, diminished reactive oxygen intermediate (ROI) production is an important consequence of impaired neutrophil function. We have studied the effect of
Hirayama, A.   +9 more
core   +1 more source

Constraints on superoxide mediated formation of manganese oxides

open access: yesFrontiers in Microbiology, 2013
Manganese (Mn) oxides are among the most reactive sorbents and oxidants within the environment, where they play a central role in the cycling of nutrients, metals, and carbon.
Deric R. Learman   +3 more
doaj   +1 more source

Copper- and Zinc-containing Superoxide Dismutase Can Act as a Superoxide Reductase and a Superoxide Oxidase [PDF]

open access: yesJournal of Biological Chemistry, 2000
The copper- and zinc-containing superoxide dismutase can catalyze the oxidation of ferrocyanide by O(2) as well as the reduction of ferricyanide by O(2). Thus, it can act as a superoxide dismutase (SOD), a superoxide reductase (SOR), and a superoxide oxidase (SOO).
S I, Liochev, I, Fridovich
openaire   +2 more sources

Bioactive Secondary Metabolites of a Marine Bacillus sp. Inhibit Superoxide Generation and Elastase Release in Human Neutrophils by Blocking Formyl Peptide Receptor 1

open access: yesMolecules, 2013
It is well known that overwhelming neutrophil activation is closely related to acute and chronic inflammatory injuries. Formyl peptide receptor 1 (FPR1) plays an important role in activation of neutrophils and may represent a potent therapeutic target in
Yin-Ting Huang   +6 more
doaj   +1 more source

COX4-1 promotes mitochondrial supercomplex assembly and limits reactive oxide species production in radioresistant GBM

open access: yesCell Stress, 2022
Glioblastoma (GBM) is a fatal disease with recurrences often associated with radioresistance. Although often effective at treating newly diagnosed GBM, increasing evidence suggests that radiotherapy-induced alterations in tumor metabolism promote GBM ...
Claudia R. Oliva   +3 more
doaj   +1 more source

Role of Protons in Superoxide Reduction by a Superoxide Reductase Analogue [PDF]

open access: yesInorganic Chemistry, 2005
Superoxide reduction by thiolate-ligated [FeII(SMe2N4(tren))]+ (1) involves two proton-dependent steps and a single peroxide intermediate, [FeIII(SMe2N4(tren))(OOH)]+ (2). An external proton donor is required, ruling out mechanisms involving H+ or H-atom abstraction from the ligand N-H.
Roslyn M, Theisen, Julie A, Kovacs
openaire   +2 more sources

Identification of a core set of rhizobial infection genes using data from single cell-types

open access: yesFrontiers in Plant Science, 2015
Genome-wide expression studies on nodulation have varied in their scale from entire root systems to dissected nodules or root sections containing nodule primordia.
Da-Song eChen   +5 more
doaj   +1 more source

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